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Anyone used Lupron with a bit of hCG for trigger??

triggr hcg lupron ivf high responder pcos ovaries cycling ohss egg quality

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#1 TryingForOur2ndChild

  • Global 100+
  • 791 posts
  • Gender:Female
  • Location:London, ON
  • Dx:Male Factor

Posted 24 October 2016 - 01:48 PM

Hello ladies... I'm currently in my 2nd round of IVF and a 'high responder' and we have severe male factor. My first cycle I had a Lupron trigger and was a freeze all. I had 22 eggs retrieved but most were premature with some too mature and only 4 made it to day-3 embryos for freezing.... long and short of it one embryo was a success out of the four and I'm really hoping for better freezing numbers this time around two years later. On my SD5 u/s it looked like I was shaping up to have a similar cycle with over 12 follicles on each side ranging 8-11mm so my puregon was dropped a bit. I wanted to know if anyone has ever had a Lupron trigger with a small amount of hCG to help with maturation if it's a freeze all and a concern of OHSS? My RE is open to hearing his patients and would like to bring whatever options I may have to the table this Thursday when I have my SD10 check. Any suggestions are appreciated. For more details on this cycle please look at signature... and to compare with 1st cycle please look at profile. Thank you again!  :)


See full journey details on my profile:


About Us:

​Trying to conceive since 2013 (male factor); Me: 39 yrs old; DH: 37 yrs old; low testosterone; very low sperm count; on Clomid for testosterone


~ 2014 ~ IVF Cycle #1:


Cycle Info:

- Antagonist protocol

- Retrieval: 22 eggs retrieved; 8 injected (ICSI); 6 fertilized; 4 embryos divided - 2 embryos are 4 cell grade 1, 1 embryo is 5 cell grade 2, and 1 embryo is 8 cell grade 2


FET #1 - medicated cycle (2014)

- transferred two day-3s: one 10 cell grade 1 and one 12 cell grade 2; Beta: BFN; approved to do a natural FET next time


FET #2 - Non-medicated cycle (2014)

- added Teva-Doxycycline 100mg (antibiotic) started one day before procedure: 1 tab 2xdaily until finished) 

- transferred two day-3 embies (1 is 10 cell grade 2 and 1 is 12 cell grade 2); took 1 tab of Apo-Diazepam (valium) 5mg 45mins before FET        

​- HPT = th_abfp.gifbanana.gifbanana.gifth_abfp.gif  Welcomed our little babygirl.gif in summer of 2015


~ 2016/17IVF Cycle #2: Project Sibling


Cycle Info:

Oct. 29: Retrieval - 23 eggs retrieved; will be a freeze all cycle

Nov. 2: Dostinex 0.5mg every other day for a total of 8 days has started to alleviate OHSS 

Nov. 4: Day 6 report: 5 embryos on ice... yay! 4 day-5s (4AA and 3 are 4BC quality) and 1 day-6 (5BC quality)


FET #1 - Non-medicated cycle (2017)

Feb. 6: start Teva-Doxycycline antibiotic100mg one day before procedure
Feb. 7: scheduled transfer at 11:45am; 1 tab of Apo-Diazepam (valium) 5mg taken 45mins before transfer; transfer of one 4AA blast

Feb.20: BETA - BFN; approved to go right into another natural FET with no cycle in between


FET #2 - Non-medicated cycle (2017)

Feb.24: CD3 - u/s and b/w= nothing said about lining; E2 19, LH 4.4 IU/L, FSH 6.6 IU/L, Prolactin 8.1 Ng/mL, TSH 2.22 IU/L, Progesterone 1.6 nmol/L, Glucose 4.1 - I requested (norm is 3.6-7.7); back on CD15; acupuncture 2x weekly until fet to try and bring on LH surge sooner than CD17.

Mar.6: OPK positive in the evening so looks like I will be going into the clinic tomorrow

Mar.7: CD14 - u/s and b/w= 11mm triple lining; E2 712, LH 32 IU/L

Mar.8: CD15 - b/w= confirmed LH surge was yesterday; E2 343, LH 8.12 IU/L; start Endometrin 3x/daily

Mar.11: start Doxycycline antibiotic 100mg (8 pills total) one day before procedure: 1 tab 2xdaily until finished

Mar.12: scheduled transfer at 10am of one 4BA blast; 1 tab of Apo-Diazepam (valium) 5mg taken 45mins before transfer

Mar.23: HPT = th_abfp.gifbanana.gifbanana.gifth_abfp.gif

​Mar.25: Beta #1= 788 hcg, Progesterone 107 nmol/L; RE happy with results so skipping beta #2 and going right to u/s

​Apr.4: had light bleeding last night so went to clinic where they did an u/s; too early to really see much but did see a gestational sac; u/s moved from Apr.8th to 15th

Apr.18: First u/s scheduled (at 8 wks).... omg there are twins!!! One had a heartbeat of 140 and the other only 80 so being referred to the head OB of internal fetal medicine as it looks like I may have a vanishing twin which RE said 50% of twins go down to one before the 2nd trimester.






#2 Ola1981

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  • Location:Saskatoon
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  • Dx:Male Factor
  • My Clinic:Aurora Reproductive Care Saskatoon

Posted 24 October 2016 - 04:40 PM

I did a dual trigger with decaptyl (similar to lupron) and hcg and am holding my daughter from that cycle :) Good luck with your upcoming cycle!!!
  • TryingForOur2ndChild likes this
See about me for details of our journey to become parents to 2 beautiful children

Also tagged with one or more of these keywords: triggr, hcg, lupron, ivf, high responder, pcos ovaries, cycling, ohss, egg quality