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Medication to control endo symptoms/inflammation during pregnancy?

Started By Lola1973 , Nov 18 2015 08:39 PM

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6 replies to this topic

#1 Lola1973

Lola1973
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Posted 18 November 2015 - 08:39 PM

I have severe (stage 4) endo and I am 12 week pregnant. I had a one-month-acting Lupron shot a few weeks before my transfer and started Prednisone  a week before the transfer. Everything went well, I became pregnant and our little one is doing well. Yesterday I started reducing my dose of Prednisone so that we completely stop it when I reach week 14... And last night I started feeling the old endo pain around my ovaries... I was wondering: Did you take some other medications during 2nd and 3rd trimesters of pregnancy to control endo symptoms/inflammation? It seems like the first trimester was the one Drs were concerned about... Maybe everything is fine and my body just needs to adjust to this change.... I guess I am just worried about the effect of this on the baby since I can feel it in a significant way myself...

 

If you have any similar experience, would you please share?

 

Thank you,


Ttc first child for both of us since February 2012

 

Surgery and diagnosis of severe endometriosis Nov. 2012

 

IVF#1 April 2013: BFP 8388.gif   9 weeks

IVF#2 Sept 2013: BFP 8388.gif   9,5 weeks

 

Clinic 2:

 

IVF#3 May 2014: Embryo banking: 4 blasts

IVF#4 July 2014: Embryo banking: 3 blasts

PGS Result August 2014: All 7 blasts are abnormal... Moving on to DE.

 

Clinic 3:

 

Transfer #1 Feb. 2015: BFN

Transfer #2 June 2015: BFN

Transfer #3 Sept 2015:  th_abfp.gif on hpt Sept 24!!!!

    1st beta      12dp3dt: 421    2nd beta     14dp3dt:1025    Viability US (6w6d): One perfect baby measuring 7.0 weeks with HB of 130!! yahoo.gif

    8- week US: Cutest little gummy bear measuring 8w1d

    Harmony test 10weeks: Risk of trisomy 13, 18 and 21 under 1 in 10,000
20-week US: Baby girl right on track!

Lilypie Pregnancy tickers        

#2 Hopeful1

Hopeful1
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  • Gender:Female
  • Location:Calgary, AB
  • Dx:Endometriosis
  • My Clinic:RFP - Calgary Now ORM - Portland, OR

Posted 19 November 2015 - 02:49 PM

I don’t really have much advise but I wanted to let you know that I too have severe stage 4 endo and when I was pregnant with my son I was also on prednisone for the first 12 weeks – was weaned off entirely on the 12th week – and I didn’t have any flare ups for the remainder of the pregnancy. Now with this pregnancy the clinic weaned me off the prednisone so I was done at 7 weeks 5 days pregnant and I still am ok as far as abdominal pain goes.

 

I know everyone is different but hopefully the farther along you become the better it will get because I think the greater production of progesterone should help with the endo.

 

Hopeful1


Me-39 DH -41
Dx: 03/07 - Stage 4 Endometriosis only one ovary left.
TTC: 8 years

March/April 2010 - #1 IVF/ICSI at RFP - 04/22 - BFN
August/September 2010 - #2 IVF/ICSI at RFP - 09/21 - BFN
January 2011 - FET #1 at RFP - 02/05 - BFN
October/November 2011 - #1 IVF/ICSI with DE at ORM - Blighted Ovum
June 2012 - FET #1 with DE at ORM - 06/22/2012 - #2 Beta 47 - Chemical - BFN

September 2013 - FET #2 with DE at ORM 05/15/2014 - Our beautiful baby boy has finally arrived!! babyboy.gif

We have 9 Frosties left

 

Sept/October 2015 - FET #3 with DE at ORM
08/31/2015 - Start Lupron
09/01/2015 - Cervical Dilation
09/10/2015 - E2 Blood Test
09/21/2015 - E2 Blood Test - 722
09/28/2015 - U/S and Blood Test

09/28/2015 - U/S and Blood Test. Lining was 8.7mm yay!! we can mover forward with the Transfer.

10/05/2015 - E2 & P4 Blood Test

10/09/2015 - Transfer Day - Transfered two beautiful 5day blasts. They had to thaw 5 in order to get two so now we have 4 remaining frosties

10/13/2015 - 4dp5dt - POAS'd and got a very faint line on the FRER. So excited, thats never happened to me before.

10/19/2015 - 10dp5dt - Beta #1 469!!

10/21/2015 - 12dp5dt - Beta #2 887!! So excited, that a 52.21h doubling time.

10/23/2015 - 14dp5dt - Beta #3 1835!! Fingers crossed!! Thats a 45.77H doubling time

11/06/2015 - OMG it's Twins!! Baby A is measing 6w5d with a HB of 122bpm and Baby B is measuring 6w4d with a HB of 116bpm

11/24/2015 - Baby A is measing 9w3d with a HB of 122bpm and Baby B is measuring 9w1d with a HB of 116bpm

12/17/2015 - NT Scan -

06/02/2016 - Our Beautiful baby Boy and Girl finally arrived today!! babyboy.gif babygirl.gif 

 

Follow our journey at http://ourtwistyturn...ey.blogspot.ca/

 

Whfym7.png

 

 

 

#3 Lola1973

Lola1973
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  • 556 posts
  • Gender:Female
  • Dx:N/A

Posted 19 November 2015 - 04:41 PM

Thank you for sharing this info with me, Hopeful. It reassures me that your protocol sounded somewhat similar. What meds are you on now?

I actually feel better today (just a little endo pain) so I guess my body is adjusting to the change.

Congrats on your pregnancy:)

Ttc first child for both of us since February 2012

 

Surgery and diagnosis of severe endometriosis Nov. 2012

 

IVF#1 April 2013: BFP 8388.gif   9 weeks

IVF#2 Sept 2013: BFP 8388.gif   9,5 weeks

 

Clinic 2:

 

IVF#3 May 2014: Embryo banking: 4 blasts

IVF#4 July 2014: Embryo banking: 3 blasts

PGS Result August 2014: All 7 blasts are abnormal... Moving on to DE.

 

Clinic 3:

 

Transfer #1 Feb. 2015: BFN

Transfer #2 June 2015: BFN

Transfer #3 Sept 2015:  th_abfp.gif on hpt Sept 24!!!!

    1st beta      12dp3dt: 421    2nd beta     14dp3dt:1025    Viability US (6w6d): One perfect baby measuring 7.0 weeks with HB of 130!! yahoo.gif

    8- week US: Cutest little gummy bear measuring 8w1d

    Harmony test 10weeks: Risk of trisomy 13, 18 and 21 under 1 in 10,000
20-week US: Baby girl right on track!

Lilypie Pregnancy tickers        

#4 9ay

9ay
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  • Gender:Female
  • Dx:Endometriosis

Posted 17 January 2016 - 10:50 AM

I too have stage 4 endo and I am feeling my best while pregnant. I am so afraid that it will come back once I give birth though :(


VF#1 Oct 2012: Long Lupron Protocol, 13 eggs retrieved, 10 mature, 8 fertilized, 2 transferred at day 3, th_abfn.gif
FET#1 Dec 2012 : 2 transferred at day 3, th_abfn.gif
Changed clinics
IVF#2 Oct 2013: Long Lupron Protocol, 11 eggs retrieved, 8 mature, 7 fertilized, 2 transferred at day 3, 5 cultured to day 5, none made it to blast , th_abfn.gif
IVF#3 Jan 2014: Long Lupron Protocol, 10 eggs retrieved, 7 mature, 5 fertilized, 3 transferred at day 3, yup same story...th_abfn.gif
IVF#4 Jun 2014: Long Lupron Protocol, 8 mature, 3 transferred at day 3, yet another th_abfn.gif
Time to change clinics
IVF#5 Jan 2015: Ultra Long Lupron Protocol (3 months of Lupron Depot therapy prior to IVF), 13 eggs retrieved, 8 mature, 5 fertilized, 2 2BB 5 day blasts with AH transferred
Beta @11dp5dt: 256.9 th_abfp.gif
Pregnant with twins. One stop growing @9 weeks.
TFMR at 21 weeks on 23 Jun 2015. Gave birth to a beautiful angel boy sad.png
IVF#6 Sep 2015 - Trying for my rainbow
Short protocol
Started stims on 31st Aug
ER on 14th Sep, 14 eggs retrieved, 13 mature, 9 fertilised, 6 divided
2 3BA 5 day blasts transferred on 19th Sep
9dp5dt th_abfp.gifyahoo.gif
Beta @11dp5dt: 738
Beta @14dp5dt: 2058 eusa_pray.gif
17dp5dt (5w1d) U/S - 6 mm gestational sac
6w2d U/S - one baby with a strong HB
18th Nov - IPS testing
23rd Nov - Risk of trisomy 13,18 and 21 under 1 in 10,000 in Panorama test
15th Dec - U/S at 15 weeks - Team PINK!

Gave birth on June 2018

 

Trying for no#2

IVF #7 Started stims on 8th of Jul, 300 gonal f + cetrotide + double trigger

ER on 20th July

17 egss retrieved, 15 mature, 12 fertilized

 

#5 Missmetal

Missmetal
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  • Gender:Female
  • Dx:Endometriosis
  • My Clinic:VFC

Posted 18 January 2016 - 07:32 PM

Hi everyone,
I have recently been diagnosed with endo. I also have diminished ovarian reserves. Has anyone had their ovarian reserves affected by having laparoscopic surgery? Woud any of you recommend laparoscopic surgery? I am unsure of what stage of endo that I currently have but they did discover an endometrioma cyst in my last ultrasound for IUI. Please help. Any information would be greatly appreciated.

Me 33 DH 39 married 2010 together since 2002 TTC 2012
Diagnosis: DOR & Endometriosis 
Mommy to one fur baby S and to one Fur baby Angel O you are forever in my heart❤️
Had left kidney removal April 2015
AMH: 1.2

4 months of clomid
IUI #1 Nov 2015 with clomid - BFN

DHEA prescribed for DOR

 

IVF#1 protocol: Suprefact, 300 Menopur, 150 Gonal F., Cetrotide. 

5-6 follies at baseline ultrasound

ER: 3 eggs - 2 ICSI did not fertilize 

1 fertilized - normal ivf fertilization 

 

#6 9ay

9ay
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  • 140 posts
  • Gender:Female
  • Dx:Endometriosis

Posted 11 March 2016 - 01:44 PM

Hi everyone,
I have recently been diagnosed with endo. I also have diminished ovarian reserves. Has anyone had their ovarian reserves affected by having laparoscopic surgery? Woud any of you recommend laparoscopic surgery? I am unsure of what stage of endo that I currently have but they did discover an endometrioma cyst in my last ultrasound for IUI. Please help. Any information would be greatly appreciated.

 

Hi. Yes my ovarian reserve decreased considerably after lap. Maybe you can ask for medical treatment.


VF#1 Oct 2012: Long Lupron Protocol, 13 eggs retrieved, 10 mature, 8 fertilized, 2 transferred at day 3, th_abfn.gif
FET#1 Dec 2012 : 2 transferred at day 3, th_abfn.gif
Changed clinics
IVF#2 Oct 2013: Long Lupron Protocol, 11 eggs retrieved, 8 mature, 7 fertilized, 2 transferred at day 3, 5 cultured to day 5, none made it to blast , th_abfn.gif
IVF#3 Jan 2014: Long Lupron Protocol, 10 eggs retrieved, 7 mature, 5 fertilized, 3 transferred at day 3, yup same story...th_abfn.gif
IVF#4 Jun 2014: Long Lupron Protocol, 8 mature, 3 transferred at day 3, yet another th_abfn.gif
Time to change clinics
IVF#5 Jan 2015: Ultra Long Lupron Protocol (3 months of Lupron Depot therapy prior to IVF), 13 eggs retrieved, 8 mature, 5 fertilized, 2 2BB 5 day blasts with AH transferred
Beta @11dp5dt: 256.9 th_abfp.gif
Pregnant with twins. One stop growing @9 weeks.
TFMR at 21 weeks on 23 Jun 2015. Gave birth to a beautiful angel boy sad.png
IVF#6 Sep 2015 - Trying for my rainbow
Short protocol
Started stims on 31st Aug
ER on 14th Sep, 14 eggs retrieved, 13 mature, 9 fertilised, 6 divided
2 3BA 5 day blasts transferred on 19th Sep
9dp5dt th_abfp.gifyahoo.gif
Beta @11dp5dt: 738
Beta @14dp5dt: 2058 eusa_pray.gif
17dp5dt (5w1d) U/S - 6 mm gestational sac
6w2d U/S - one baby with a strong HB
18th Nov - IPS testing
23rd Nov - Risk of trisomy 13,18 and 21 under 1 in 10,000 in Panorama test
15th Dec - U/S at 15 weeks - Team PINK!

Gave birth on June 2018

 

Trying for no#2

IVF #7 Started stims on 8th of Jul, 300 gonal f + cetrotide + double trigger

ER on 20th July

17 egss retrieved, 15 mature, 12 fertilized

 

#7 9ay

9ay
  • Global 100+
  • 140 posts
  • Gender:Female
  • Dx:Endometriosis

Posted 07 February 2017 - 03:42 PM

Gave birth 8 months ago and endo is not back yet. Praying that it will never come back!


VF#1 Oct 2012: Long Lupron Protocol, 13 eggs retrieved, 10 mature, 8 fertilized, 2 transferred at day 3, th_abfn.gif
FET#1 Dec 2012 : 2 transferred at day 3, th_abfn.gif
Changed clinics
IVF#2 Oct 2013: Long Lupron Protocol, 11 eggs retrieved, 8 mature, 7 fertilized, 2 transferred at day 3, 5 cultured to day 5, none made it to blast , th_abfn.gif
IVF#3 Jan 2014: Long Lupron Protocol, 10 eggs retrieved, 7 mature, 5 fertilized, 3 transferred at day 3, yup same story...th_abfn.gif
IVF#4 Jun 2014: Long Lupron Protocol, 8 mature, 3 transferred at day 3, yet another th_abfn.gif
Time to change clinics
IVF#5 Jan 2015: Ultra Long Lupron Protocol (3 months of Lupron Depot therapy prior to IVF), 13 eggs retrieved, 8 mature, 5 fertilized, 2 2BB 5 day blasts with AH transferred
Beta @11dp5dt: 256.9 th_abfp.gif
Pregnant with twins. One stop growing @9 weeks.
TFMR at 21 weeks on 23 Jun 2015. Gave birth to a beautiful angel boy sad.png
IVF#6 Sep 2015 - Trying for my rainbow
Short protocol
Started stims on 31st Aug
ER on 14th Sep, 14 eggs retrieved, 13 mature, 9 fertilised, 6 divided
2 3BA 5 day blasts transferred on 19th Sep
9dp5dt th_abfp.gifyahoo.gif
Beta @11dp5dt: 738
Beta @14dp5dt: 2058 eusa_pray.gif
17dp5dt (5w1d) U/S - 6 mm gestational sac
6w2d U/S - one baby with a strong HB
18th Nov - IPS testing
23rd Nov - Risk of trisomy 13,18 and 21 under 1 in 10,000 in Panorama test
15th Dec - U/S at 15 weeks - Team PINK!

Gave birth on June 2018

 

Trying for no#2

IVF #7 Started stims on 8th of Jul, 300 gonal f + cetrotide + double trigger

ER on 20th July

17 egss retrieved, 15 mature, 12 fertilized

 

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