3 replies to this topic

Background - I am 33 my husband is 39 we have a nearly 3 year old daughter conceived naturally. TTC for 21 mos.
My test were all normal. Husband's morphology was very low - 2% then 0% on next test also low motility.
Doctor suggested ICSI as our best shot given morphology issues.
Tried one round IUI - negative
Stim for 13 days then hCG - 22 follicles at retrieval - 22 eggs - 15 mature
11 were ICSI with 10 fertilizing
4 were IVF (just to check if it worked at my request) and 3 fertilized
At day 3 most looked excellent quality and 4 were 7 cell 3 were 6 cell 2 were 5 cell the others were lower count or only "good" quality
At day 5 only 1 blastocyst and it had alot of fragmentation. 6 morulas, others had arrested
Of the morulas 2 were considered "excellent" and one of those were cavitating - those 2 were transfered. The other 4 morulas were considered "good" quality. One of those was considered and excellent quality blastocyst on day 6 and that one was frozen.

My question is on the success rates of morulas at day 5 (given they are a little slow). I find very mixed literature online.

I know it varies by clinic, but in general I would like to know compared to blastocysts. (My clinic has a 62% clinical pregnancy success rate for blastocysts in patients under 35 but I am assuming morulas are much lower.)

Thanks!
Martha

[Peter]

Background - I am 33 my husband is 39 we have a nearly 3 year old daughter conceived naturally. TTC for 21 mos.
My test were all normal. Husband's morphology was very low - 2% then 0% on next test also low motility.
Doctor suggested ICSI as our best shot given morphology issues.
Tried one round IUI - negative
Stim for 13 days then hCG - 22 follicles at retrieval - 22 eggs - 15 mature
11 were ICSI with 10 fertilizing
4 were IVF (just to check if it worked at my request) and 3 fertilized
At day 3 most looked excellent quality and 4 were 7 cell 3 were 6 cell 2 were 5 cell the others were lower count or only "good" quality
At day 5 only 1 blastocyst and it had alot of fragmentation. 6 morulas, others had arrested
Of the morulas 2 were considered "excellent" and one of those were cavitating - those 2 were transfered. The other 4 morulas were considered "good" quality. One of those was considered and excellent quality blastocyst on day 6 and that one was frozen.

My question is on the success rates of morulas at day 5 (given they are a little slow). I find very mixed literature online.

In general terms a morula is just less than a blastocyst in terms of success rate for a given clinic.

I know it varies by clinic, but in general I would like to know compared to blastocysts. (My clinic has a 62% clinical pregnancy success rate for blastocysts in patients under 35 but I am assuming morulas are much lower.)

No, morula success rate would be around 55% in this context.

Good luck!

Peter

Thanks!
Martha

I just wanted to thank you again for helping keep me sane as I had read some really negative things about 5 day morulas.

I finally had my blood test today. It was positive! 14 days past 5 day transfer and my hCG was 738. They tell me this is good. It is something that every site has listed differently but seems good in general.

Thanks Again,
Martha

[Peter]

I just wanted to thank you again for helping keep me sane as I had read some really negative things about 5 day morulas.

I finally had my blood test today. It was positive! 14 days past 5 day transfer and my hCG was 738. They tell me this is good. It is something that every site has listed differently but seems good in general.

Thanks Again,
Martha

Congratulations!

Good luck!

Peter