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may infertility be hereditary?


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#1 cafi

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Posted 18 June 2015 - 02:10 PM

Hi, My sister has tried to conceive a baby for years without succes, one eutopic and 4 m/c, me after my first son, I have had 3 m/c in less than 2 years.

may infertility be hereditary?

thanks



#2 ilovemydogs

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Posted 18 June 2015 - 03:27 PM

In my case some of my issues run in the family (fibroids and endometriosis in particular), so my original diagnosis seems to be. I've had other issues since then that are mostly due to age.
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#3 Heregoesnothing

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Posted 18 June 2015 - 10:25 PM

I've always wondered. Our issues are MF and on dh's side of the family, 3 of his uncles (from the same side of the family) struggled to conceive. 1 adopted, 1 did fertility drugs, and 1 was able to conceive naturally after 8 years and only once.

Anxious to hear others responses. I have heard that my son has greater chances of having issues since dh had them.

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#4 Meary

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Posted 19 June 2015 - 12:15 PM

I seem to be the only person in my family (only know my mother's side) who has had issues.  My sisters had children without intervention.  My mother had 4 children.  All of her brothers and sisters (8 of them) have had multiple children.  Anomalous me!

 

On my husband's side, he had an aunt who had difficulty, but conceived without assistance, with an advanced maternal age, and his mom had two children without intervention as well, though much younger.

 

What a crapshoot!


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#5 breezyboo

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Posted 23 June 2015 - 10:46 AM

I believe their are environmental factors/medications/vaccinates etc that cause infertility so its likely people in that household would be exposed to those same things.

My husband is completely infertile and his only sister tried for 12 years naturally and with IUI's & was unable to get pregnant until she did IVF. All their testing was normal.


Me: 30 Hypothyroid, Endo, MTHFR, elevated Cytokines,TNF 36.8 (13.2-30.6) IFN 27.5(5.8-20.5). 2006-Twin m/c @ 8wks w/ex BF followed by 22 BFN's ... 6 months on clomid & 4 IUI's. Married for 5yrs to the love of my life. We want to make that love childDH: 31 Azoospermia (NOA) FSH 28.3, LH & testosterone levels normal Normal genetics. NOA possibly due to injury when younger.IVF/ICSI Barbados 201312/3-ER! 18 eggs, 12 mature & 10 fertilized!12/8-ET! 2 beautiful beans snuggled into place! 7 snowflakes!12/13- BFP12/17- Beta 9dp5dt 255!12/19 Beta 11dp5dt 392, 13dp5dt 585???12/26 Beta 3,388!1/2 U/S TWINS!! HB's 122& 1211/20 U/S Lost Baby B @ 7-8 weeks. Baby A doing great!IT'S A BOY!!!4/29 @ 6 months our sweet boy became an angel ABSOLUTELY HEARTBROKEN  FET January 2015 CANCELLED thin lining WTF?FET September 2015 CANCELLED due to a cyst/delayed period...You gotta be kidding me?!FET October 2015 BFN ICSI/PGS Banking @ MCRM Feb & May 2016Feb & May 2016= 3 girls & 4 boys
FET October 13 2016 1 PGS normal girl = BFP!!!!! :D

#6 CdnHockeyGal

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Posted 23 June 2015 - 01:17 PM

I believe their are environmental factors/medications/vaccinates etc that cause infertility so its likely people in that household would be exposed to those same things.

My husband is completely infertile and his only sister tried for 12 years naturally and with IUI's & was unable to get pregnant until she did IVF. All their testing was normal.

 

I am not familiar with any medical research that supports that vaccines cause infertility.  It is my understanding that generally genetics (hereditary) and/or environmental factors can play into an IF diagnosis.  Do you have any medical journal articles supporting that vaccines cause infertility to share?


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#7 breezyboo

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Posted 23 June 2015 - 04:21 PM

There is load of information online about vaccines and ingredients in them linked to infertility. Such as polysorbate 80. Its obviously a controversial topic but you can research it and form your own opinion.

http://healthimpactn...se-infertility/


http://articles.merc...nfertility.aspx
Me: 30 Hypothyroid, Endo, MTHFR, elevated Cytokines,TNF 36.8 (13.2-30.6) IFN 27.5(5.8-20.5). 2006-Twin m/c @ 8wks w/ex BF followed by 22 BFN's ... 6 months on clomid & 4 IUI's. Married for 5yrs to the love of my life. We want to make that love childDH: 31 Azoospermia (NOA) FSH 28.3, LH & testosterone levels normal Normal genetics. NOA possibly due to injury when younger.IVF/ICSI Barbados 201312/3-ER! 18 eggs, 12 mature & 10 fertilized!12/8-ET! 2 beautiful beans snuggled into place! 7 snowflakes!12/13- BFP12/17- Beta 9dp5dt 255!12/19 Beta 11dp5dt 392, 13dp5dt 585???12/26 Beta 3,388!1/2 U/S TWINS!! HB's 122& 1211/20 U/S Lost Baby B @ 7-8 weeks. Baby A doing great!IT'S A BOY!!!4/29 @ 6 months our sweet boy became an angel ABSOLUTELY HEARTBROKEN  FET January 2015 CANCELLED thin lining WTF?FET September 2015 CANCELLED due to a cyst/delayed period...You gotta be kidding me?!FET October 2015 BFN ICSI/PGS Banking @ MCRM Feb & May 2016Feb & May 2016= 3 girls & 4 boys
FET October 13 2016 1 PGS normal girl = BFP!!!!! :D

#8 mouse

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Posted 23 June 2015 - 05:50 PM

Clearly people bring their own opinions and biases to these sorts of questions which is well and good for healthy exchange and debate. 

 

It's wise to keep in mind that there's a load of online information about lots of things - being online doesn't make the info factual or credible. 

 

http://lindahoodsigmontruth.com/dna-proof-that-jesse-is-elvis-aron-presley/ 

 

Just sayin'


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#9 CdnHockeyGal

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Posted 23 June 2015 - 06:04 PM

Clearly people bring their own opinions and biases to these sorts of questions which is well and good for healthy exchange and debate. 

 

It's wise to keep in mind that there's a load of online information about lots of things - being online doesn't make the info factual or credible. 

 

http://lindahoodsigmontruth.com/dna-proof-that-jesse-is-elvis-aron-presley/ 

 

Just sayin'

 

I think this is very well said.  In my opinion, I think it's terribly important for anyone doing any type of research on infertility to ensure they are utilizing medical journals and peer reviewed articles while consulting with their RE.


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It was long, awful & hard. We got very lucky and didn't run out of both emotional and financial resources. We saw some of the most beautiful of people in our lowest moments. Baby Girl arrived Apr 10/2018

#10 breezyboo

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Posted 23 June 2015 - 08:57 PM

Respectfully, these are medical professions not bogus websites. Vaccines can cause extreme damage to the immune system. This IS proven. The CDC hasn't paid out BILLIONS in vaccine injury cases for no reason.
I am a vaccine injured person myself. After my routine vaccines as a child I got very sick and developed immediate severe psoriasis. I also have hypothyroidism & endometriosis which are all immune related disorders.
Have you read the ingredient lists on vaccines? One can't possibly think that injected so many toxic chemicals in your system with absolutely zero reprocusions.
Me: 30 Hypothyroid, Endo, MTHFR, elevated Cytokines,TNF 36.8 (13.2-30.6) IFN 27.5(5.8-20.5). 2006-Twin m/c @ 8wks w/ex BF followed by 22 BFN's ... 6 months on clomid & 4 IUI's. Married for 5yrs to the love of my life. We want to make that love childDH: 31 Azoospermia (NOA) FSH 28.3, LH & testosterone levels normal Normal genetics. NOA possibly due to injury when younger.IVF/ICSI Barbados 201312/3-ER! 18 eggs, 12 mature & 10 fertilized!12/8-ET! 2 beautiful beans snuggled into place! 7 snowflakes!12/13- BFP12/17- Beta 9dp5dt 255!12/19 Beta 11dp5dt 392, 13dp5dt 585???12/26 Beta 3,388!1/2 U/S TWINS!! HB's 122& 1211/20 U/S Lost Baby B @ 7-8 weeks. Baby A doing great!IT'S A BOY!!!4/29 @ 6 months our sweet boy became an angel ABSOLUTELY HEARTBROKEN  FET January 2015 CANCELLED thin lining WTF?FET September 2015 CANCELLED due to a cyst/delayed period...You gotta be kidding me?!FET October 2015 BFN ICSI/PGS Banking @ MCRM Feb & May 2016Feb & May 2016= 3 girls & 4 boys
FET October 13 2016 1 PGS normal girl = BFP!!!!! :D

#11 CdnHockeyGal

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Posted 23 June 2015 - 09:25 PM

I'm very sorry to hear of your health concerns - I wish you and your medical team great success in dealing with them.

 

I think we will have to respectfully disagree Breezyboo as it pertains to vaccines.  I believe them to only be favorable and am very grateful these important health management tools exist.  As I do not personally have an advanced science degree I rely on the medical community to evaluate the efficacy and safety of the ingredients in vaccine and am comfortable with the advice they give me.  If I have personal concerns I seek the counsel of my cousin and several friends who hold a PhDs in microbiology with specializations in immunology.

 

I believe it's very important for us to be active partners in managing our health and to read up on our conditions to be able to make the best decisions for managing our particular health care concerns.  I would encourage anyone with concerns about their health to draw their readings from a wide variety of medically reputable sources and have a detailed conversation with their medical team.


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It was long, awful & hard. We got very lucky and didn't run out of both emotional and financial resources. We saw some of the most beautiful of people in our lowest moments. Baby Girl arrived Apr 10/2018

#12 mouse

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Posted 24 June 2015 - 06:17 AM

I also am sorry to hear of your health problems and hope that things work out how you want.  

 

While the sites may not be bogus (whatever that means in the internet context), they are clearly agenda driven. And for what it's worth, I have read the list of ingredients on quite a few vaccines

 

Lots of studies have found lots of things - often conflicting things - and, even leaving aside design issues such as sample size,  animal versus human, length of follow up, control for confounders etc. - those studies are open to being misrepresented by all sides in an argument.  The Slovakian mouse study (1993) referenced above, for instance, found changes in the cycles and reproductive organs of female mice injected with polysorbate 80 but did not report on their fertility/infertility per se. The changes might well have impacted fertility in mice but the study didn't report on that because they killed the mice for histological review before they were bred so at best it's extrapolation and at worst, a misrepresentation to say polysorbate 80 causes infertility based on this study. 

 

Articles, not unlike studies, don't always provide the whole picture either. Polysorbate 80 (derived from natural sorbitol and plant-based oleic acid) is found in much much more than vaccines - the average person in North America or Europe consumes about 100 mg of it daily - it's in vitamins/supplements, mouthwash, cosmetic/hygiene products, and food so it may be a bit of a stretch to lay the blame for any polysorbate 80 related infertility that might possibly exist on vaccines alone. 

 

Of course there's always the chance that a study just reflects bad science - Andrew Wakefield comes to mind.

 

Also for what it's worth, it's not uncommon for individuals, companies, and/or agencies to pay to settle cases without there necessarily being any proof or admission of error, responsibility, or guilt simply because of the time/money involved and the bad blood that a court case may cause as well as for the "greater good".

 

 

As I noted above, diverse opinions and viewpoints make for useful discussion and like CHG, I'd encourage everyone to research for themselves - not just for vaccines but for all significant decisions.  At this point I think we've gone pretty far off the original question for the RE so I won't derail the topic further


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#13 Aiglee

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Posted 24 June 2015 - 10:18 AM

Bringing back the topic to inheriting infertility ( :) ), I think it would depend on what type of infertility it is. In my particular case my mom struggled to have me (first child) and every doctor told her she could not get pregnant. She stopped trying and gave up, then at some point she started losing hair and got prescribed something like Vitamin B injections (too much time has passed and that's as much as my parents remember) and got told she would get pregnant. They laughed it off but here I am. After that my middle sister was 3 years later and the youngest one came from tied tubes!! 

 

I have been using vitamin B to see if it's the same, so far no luck. On the other hand my middle sister got pregnant pretty much without trying. 

 

I don't know if it's hereditary but I would love more research on the subject. I also believe environmental factors would be a huge influence, but don't believe is caused by vaccines.


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#14 breezyboo

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Posted 24 June 2015 - 03:29 PM

Its ok, I know Ill never win the debate on boards so I don't waste my time. I will say though I am not 100% anti-vaccination but I am for vaccine education. Just because the government deems it "safe" doesn't mean it is. There are many vaccines that have been discontinued and/or modified over the decades due to ingredients they found out to be harmful.

Think about how many medications they release all the time then x amount of years later recall them after so many people reported adverse reactions, deaths, birth defects etc. They fast track these drugs and then deal with the consequences later. Our kids are the most vaccinated and the also the sickest.


Me: 30 Hypothyroid, Endo, MTHFR, elevated Cytokines,TNF 36.8 (13.2-30.6) IFN 27.5(5.8-20.5). 2006-Twin m/c @ 8wks w/ex BF followed by 22 BFN's ... 6 months on clomid & 4 IUI's. Married for 5yrs to the love of my life. We want to make that love childDH: 31 Azoospermia (NOA) FSH 28.3, LH & testosterone levels normal Normal genetics. NOA possibly due to injury when younger.IVF/ICSI Barbados 201312/3-ER! 18 eggs, 12 mature & 10 fertilized!12/8-ET! 2 beautiful beans snuggled into place! 7 snowflakes!12/13- BFP12/17- Beta 9dp5dt 255!12/19 Beta 11dp5dt 392, 13dp5dt 585???12/26 Beta 3,388!1/2 U/S TWINS!! HB's 122& 1211/20 U/S Lost Baby B @ 7-8 weeks. Baby A doing great!IT'S A BOY!!!4/29 @ 6 months our sweet boy became an angel ABSOLUTELY HEARTBROKEN  FET January 2015 CANCELLED thin lining WTF?FET September 2015 CANCELLED due to a cyst/delayed period...You gotta be kidding me?!FET October 2015 BFN ICSI/PGS Banking @ MCRM Feb & May 2016Feb & May 2016= 3 girls & 4 boys
FET October 13 2016 1 PGS normal girl = BFP!!!!! :D

#15 Pegara

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Posted 30 June 2015 - 11:23 PM

In my case I'm pretty sure it is, although we don't know the cause. My mother was TTC with me for three years, but conceived my brother within two months. My maternal grandmother was TTC for four years with my mother, then tried for another 15 after that before stopping. We have been trying for six years and are starting IVF this month as our last option. It has to be hereditary to some extent.
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Diagnosed with complex hyperplasia with atypia Nov 2010, megace treatment for 18 months
May 2012 diagnosed with hyperplasia again, megace treatment for 10 months
One round Clomid October 2013
Diagnosed hyperplasia AGAIN Nov 2013, megace treatment 4 months
Rejected as patient from Aurora due to high BMI
Accepted as patient at RFP - August 2014.
First consult with RE at RFP - Oct 2014.
Three rounds of Clomid - Nov 2014, Feb & March 2015. - all BFN
IVF -July 2015 - 1 blast (5 day) transferred, 4 frozen. - BFN

#16 WishinNhopin

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Posted 14 July 2015 - 05:12 PM

You very much wonder if it's hereditary or not. ..my mom was told she couldn't have any kids due to some medical issue...she conceived naturally and gave birth to 5 all naturally. I have 2 sisters with 6 kids each...and here I am not 1..trying so desperately. With a diagnosis at this time of blocked tubes.

#17 Kitty2011

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Posted 14 July 2015 - 08:12 PM

My sister and I are both unexplained and both had to go through ivf. The first thing my RE asked me at my initial appointment was whether I had sisters with fertility issues. So in our case I think it could be genetic . Interesting thread!

#18 Merry33

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Posted 14 July 2015 - 09:46 PM

It definitely simply depends on what exactly the problem is. IF is not just "one diagnosis". For example, some severe male IF cannot be genetic, as the man wouldn't exist if it was (i.e., if the father had no or very little sperm, no conception would have ever taken place). Other things for sure have a hereditary linkage/pattern. And although we often forget - IF issues are not always one-sided - sometimes, both partners have some degree of issues, which then makes it even more complicated.


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#19 smurfette_w

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Posted 15 July 2015 - 01:26 AM

My DH has low sperm count (and quality), his brother had no problems conceiving twice back-to-back (though one passed at about 4-5 months in utero and we don't know why), and DH's parents conceived them both with a 5 year gap.  My DH has wondered whether or not his father had sperm issues as well, but no one will really know.  However, the urologist did say that my DH's condition is likely hereditary and his poor diet doesn't help the situation.

 

Another friend of ours as well as his brother both have azoospermia (don't know which type) and both needed ICSI to conceive.  At the same time, his parents conceived them both about 3 years apart and if his dad had azoospermia, he wouldn't have had any children at all.

 

Interesting topic though.


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#20 SunshineTTC

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Posted 15 July 2015 - 11:01 AM

For what it's worth, the Mercola website is well-known as completely agenda-driven (not to mention selling products) and not a reputable site whatsoever.  The guy has received several FDA warnings and has been thoroughly knocked down by the medical community and real science.  I do personally have an advanced science degree, not that this makes me any wiser than the very wise CdnHockeyGal!


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