Fainter BFP at 6w1d? Beware of the "hook effect" - IVF/FET/IUI Cycle Buddies - IVF.ca Forums

Jump to content



Photo
- - - - -

Fainter BFP at 6w1d? Beware of the "hook effect"

HPT BFP Hook effect

  • Please log in to reply
3 replies to this topic

#1 Traveladdict

Traveladdict
  • Member
  • 17 posts
  • Gender:Female
  • Dx:DOR
  • My Clinic:Astra

Posted 15 April 2015 - 11:59 AM

Hi!

 

I recently ordered more HPTs thinking to myself seeing BFPs would reassure me until the first ultrasound. I received them yesterday so I tested this morning with FMU at 6w1d. I was quite surprised to see that the test line was a lot fainter than the control line given I expected to see a dark BFP... This kinda got me upset at first, thinking this was a bad sign...

Attached File  IVF#1 HPTs.jpg   16.71KB   2 downloads

 

Half crying, I decided to consult Dr Google. After over 2 years of infertility, I really thought I had read everything there is to read about TTC, DOR, supplements, OPKs, HPTs... Well, I learned something new today when I came across the "hook effect". Being a scientist, I dug a little deaper and found this great article, which explains it really well: http://www.medscape....rticle/778183_1

 

Basically, some variants of hCG increase significantly in early pregnancy and this can interfere with the "sandwich" formation of the HPTs. Diluting urine (see pic: I did 1/15 dilution) can reveal a darker BFP! How cool is that?! I'm such a science geek wink.png

 

3 more days to go until the first ultrasound smile.png

 

 


  • ladylazarus likes this

Me (32) - DOR

Him (33) - MFI (10-20% motility, 0-5% morphology)

Jan 2013: started TTC

Jan 2014: first consult with RE; Mar 2014: dx with DOR (AFC:7, FSH:12.5), started 75mg DHEA and 600mg co-q10 daily

Jul-Oct 2014: FSH varrying between 3.5 and 6.5! ... IUIs #1-4 (3 x femara + 1 x overlap(femara+gonal-f) all BFN

Feb 2015: DH had follow-up with urologist, no varicoceles detected, DNA fragmentation is 9.77! Prescribed Clomid

Feb 2015: IVF 1.0 (AFC:7; FSH:?) - Antagonist protocol (no BCP): 300-375IU gonal-f ... cancelled due to poor response converted to IUI#5, BFN

Mar 2015: IVF 1.1 (AFC: 9; FSH:6.5) - microflare protocol (no BCP): 10 units diluted lupron twice daily + 375IU gonal-f daily:  5R/5M/5F-ICSI (2015-03-17), transferred 1 day 5 embryo grade 5AB (2015-03-22); froze 2 early blasts (grade 1BB) on day 6 Faint BFP at 5dp5dt... Beta#1 (10dp5dt): 391, beta#2 (12dp5dt): 1097! First US (2015-04-17): measuring 6w1d, 117bpm, EDD: Dec 10

May 2015: DH had follow-up with urologist, Clomid did nothing


#2 Meary

Meary
  • 1000+
  • 1156 posts
  • Gender:Female
  • Location:Cattletown, AB
  • Interests:Animals, Crochet/Knitting/Sewing, Vespas, Horror Movies, My Job, Camping, Music
  • Dx:Unexplained
  • My Clinic:Foothills RFP

Posted 15 April 2015 - 12:12 PM

Very interesting!  Well done with your google research ;)


See Profile / About me page.


#3 kristeen033

kristeen033
  • Cyclebase
  • 498 posts
  • Gender:Female
  • Location:Fairview, Alberta
  • Dx:Tubal
  • My Clinic:Regional Fertility Clinic

Posted 15 April 2015 - 02:07 PM

I have always  gotten a darker positive on second morning or early afternoon urine than on FMU. I have read lots of women that say they get the darkest results in the evening. Very interesting.


Me: 37, Tubal Ligation 2002, Tubal Reversal 2008
DH: 34, Normal
DS 16yrs & DD 14yrs from previous marriage
Trying for 7 years
November 2009 - BFP - Chemical Pregnancy
September 2011 - Clomid 3 rounds all BFN
March 2012 - Start IVF #1 at RFP in Calgary
April 2012 - 16 eggs retrieved, 14 fertilized, 8 5 day blasts
Transfered 1 hatching blast - BFP!!!!! 7 blasts frozen.
May 2012 - 7 week U/S - baby measured good and had heartbeat
June 2012 - Stopped Prometrium 10 weeks, started bleeding 3 days later, U/S showed baby died right after 7 week U/S
August 25, 2012 - Start Suprefact for FET #1
September 8, 2012 - Start Estrace
September 21, 2012 - U/S Booked!
September 26, 2012 - FET Transferred one perfect blast. F/X
October 6, 2012 - 10dp5dt BFFN
October 9, 2012 - POAS test at Doctor's Office BFN
November 27, 2012 - Start Suprefact for FET #2
December 29, 2012 - U/S Booked
January 3, 2013 - Transferred One Hatching Blast!!! Still have 3 more in the freezer
January 10, 2013 - 7dp5dt - HPT - BFP!!!!!!
January 15, 2013 - Beta 96
January 17, 2013 - Beta 16 = Chemical Pregnancy
January 19, 2013 - FRER HPT - BFFN
June 6, 2013 - FET #3 - Starting Suprefact...hoping third time is the charm!
July 3, 2013 - U/S Booked
July 9, 2013 - FET date!!!
July 20, 2013 - 11dp5dt HPT = BFN sad.png
July 2014 - Fresh IVF Cycle Estrogen Priming Protocol

August 2, 2014 - 24 eggs retrieved!

August 3, 2014 - 11 Eggs fertilized

August 7, 2014 - Transferred 1 beautiful blast. 3 more frozen.

August 8, 2014 - Got call from clinic 6 more blasts frozen!!!  9 snow babies total and one in the oven smile.png

August 20, 2014 - First beta BFN

February 1, 2015 - FET Natural Cycle - Transferred 2 blasts one hatched. FXFX!!!

February 6, 2015 - POAS even though I know it's early...and surprise...BFP!!!!

February 10, 2015 - 9dp5dt - BFP on Clearblue Digital!!!!! th_abfp.gifyahoo.gif

February 19, 2015 - Beta 8928!!!! EDD Oct 23/15

March 7, 2015 - Ultrasound shows TWINS!!!! 2 little beans measuring 8 weeks with two little flutters for heartbeats preggo.gif

March  31, 2015 - 11 Weeks U/S. Baby A measures 11w3d Baby B measures 11w5d!!!!

May 2015 - 5 month ultrasound. Both babies look fantastic!!!! TEAM GREEN!!!giggle.gif

October 5, 2015 - C-Section date booked to meet my little babes!!! Can't wait the countdown is on!!!!!

September 19, 2015 - Babies decided to make an early appearance at 35 weeks 4 days!!!

Connor Melvin - Born 5:11am weighing 4lb15oz

Emily May - Born 5:13am weighing 5lb8oz

We are so in love! babygirl.gifbabyboy.gif

 

 

 


#4 MollyBaby

MollyBaby
  • Just Hatched
  • 1 posts
  • Dx:Unexplained

Posted 27 April 2015 - 01:29 AM

Lol. "Dr Google". That's the first time I've heard that. It's 130am and I snorted a laugh and woke my DH.





Also tagged with one or more of these keywords: HPT, BFP, Hook effect