Posted 28 October 2014 - 02:16 PM
Found this study in a group I'm in. Thoughts??? Comments?? I'm thinking this may very well be our issue. I gave a son up for adoption 19 years ago when I was a teen. Since then nothing but heartache and miscarriage. Any thoughts??
http://www.ivf1.com/...se-miscarriage/
Me-38 DH- 42
TTC since 2000
Unexplained Secondary Infertility (Had a son while a teen and gave him up for adoption)
March 2000- M/C @ 11 weeks
January 2001- M/C @ 9 weeks
February 2003- M/C @ 8 weeks
2004-2007- 6 Cycles of clomid and natural conception- BFN
November 2009- IUI with injectables- BFN
February 2010- IUI with injectables- BFN
May 2012-Consult with KRF. Re-due blood tests and prep for IVF
June 2012-Started taking Estrace for estrogen priming protocol
Blood test to see why af hasn't started. BFP with low numbers. Chemical Pregnancy
IVF#1 (KRF/Genesis)--July 29, 2012- Estrogen Priming Protocol
August 19-Egg Retrieval 20 eggs; 18 fertilized; 11 made it to Day 5
August 24- Transferred 1 Blast; Froze 4 (the rest didn't make it overnight to Day 6)
Sept 2-Took HPT (Faint Positive)
Sept 5-Beta 3 (BFN--Another Chemical)
FET#1(KRF/Genesis)-Oct 30 2012 On Estrace and Prednisone. Transferred 2 blasts (Had to thaw 3-one didn't make it. One left in the freezer)
Nov 13 2012- Beta- BFN
FET#2(KRF/Genesis) -Nov 16,2013 BETA Nov 27--Chemical Pregnancy
IVF#2 (KRF/Olive)Consult Jan 27. (Doing CCS & immune treatments this cycle)
Estrogen Priming Starts February 19, 2014 YAY!!!!
STIMS START March 1, 2014
Retrieval Mar 13, 2014. 17 eggs retrieved, 16 of which mature and 15 fertilized.
11 made it to blast and were biopsied and frozen. 5 NORMAL BLASTS 
FET with next af (transfer May, hopefully).
FET transfer with One Normal Perfect Embryo May 15, 2014
5dp5dt--Faint positive on hpt. Darker on 6dp5dt
BETA--May 26, 2014 (FX this is it)
ANOTHER F**KING chemical--beta 21 
FET#2--Lining scan on July 15. Lining at 10mm and dominate follicle is at 19mm. Waiting on ovulation to time transfer. Here we go again. FX this is it!!!
TRANSFER July 21, 2014--1 PGS Normal Blast
8th confirmed Chemical
LOOKING FOR A SURROGATE. Still have 3 PGS normal embryos frozen.
Trying again with my body......'initial' consult is April 14
Posted 28 October 2014 - 05:14 PM
this is a very interesting study and sounds like it was very thorough. Unfortunately, PGD for gender selection is not allowed in Canada, but allowed in the US (not sure if state-specific).
___________________
Me: genetic issues
DH: genetic issues, MFI
TTC since Summer 2009
See my profile for details
Posted 05 November 2014 - 12:04 AM
Hi there; that is a very interesting study. I am experiencing a non-viable pregnancy from my first FET of a CCS normal embryo. Diagnosis is male factor. I've read a couple of research papers that suggested sperm dna fragmentation can cause an embryo with a normal karyotype to stop developing. Have any of you ever asked your RE about that? I don't think my RE believes in sperm dna fragmentation. We had our embryos tested at Natera and 2 of them did have sperm chromosome abnormalities. I'm just wondering if that could still be at issue……Would welcome your thoughts.
T
ICSI #1 (freeze-all with PGS) - Sept. 2014
-28 eggs retrieved; 17 mature; 15 fertilized; 7 blastocysts sent for PGS
-PGS results = 2 normals, 2 'no signal', 3 abnormals
FET #1 (one euploid embryo) - Oct. 10, 2014
Low Positive. Turned out to be an Interstitial Ectopic Pregnancy. Methotrexate administered at 7 weeks.
FET #2 (one euploid and one 'no signal') - Feb. 3, 2015
BFP!
Beta #1 at 9dp6dt = 361 
Beta #2 at 11dp6dt = 1117
Viability Ultrasound March 5 = TWINS! Both babies measuring on track with heart beats of 141 bpm.
First Trimester Screening April 6 = both babies measuring ahead, heart beats of 165 bpm and no genetic issues. This crazy sh*t is getting real! 
Posted 09 January 2015 - 10:13 AM
Hi there- I am in this same exact boat! And I know a bunch of ladies on another forum that are as well. I've done PGS testing but my clinic will not disclose the sex of the embryo so I have no way of knowing ahead of time. They will tell me after I am pregnant or if all embryos fail I think.
Me: 33 DH: 44
Tried Clomid, 4 IUIs and 2 NCIVFs before going to full IVF
IVF #1: Nov'11 (19 eggs, 3frt., 3 day-5 blasts) 1xfer., 2 frozen BFN
FET #1: Jan'12 chem.
IVF #2: April'12 (28 eggs, 10 mtr./8 frt.) 1 blast xfer., 4 frozen BFP
DS born Jan'13
4 FETs Oct'13-May'14=BFN
IVF #3: July'14 (25 eggs, 14 mtr./14 frt.) 4 blasts (3 normal), 1 5AA xfer.=BFN (2 frozen)
Sept.'14 Remove tubes (hydro)
FET #6: Nov'14 chemical
FET #7: Jan 22, 2015
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