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Disabilities in children maybe from icsi ivf


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#1 poohbear1970

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Posted 04 February 2014 - 07:08 PM

Has anyone done icsi before and now have a child with learning disabilities  and speech delay ?

 

My daughter was born  in  2006  and has struggled with many delays  . 

 

I was never informed doing icsi might cause these disabilities  from genesis .

 

Searching online now so many studies done now on icsi disclosing all the risks involved .

 

 

 

 



#2 rollergirl

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Posted 04 February 2014 - 08:17 PM

Having a baby is a crap shoot and there are so many different variables that one can not attest to what causes what. Sorry you are dealing with what you are dealing with. I have identical twins which are very different.....how did that happen? No one knows....it is what it is.

 

Good luck.


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#3 mouse

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Posted 04 February 2014 - 08:34 PM

Sorry to hear of your daughter's struggles. I hope things get easier for you both.

 

When we started down the IVF road in 2009, we were given material that noted the potential icsi risks and also stated that there may be risks that aren't yet known - maybe it was different in 2006. Like Rollergirl said, anytime you mix DNA - whether unassissted or assisted - it's a crap shoot.  We rolled the dice because we wanted to maximize the chances of having a baby. FWIW I have friends with non-ART children that have disabilities including learning disabilities; so far my icsi girl appears perfectly fine but we'd think our family was perfect even if she had problems.


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#4 JacMac

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Posted 04 February 2014 - 10:09 PM

Unfortunately there's no guarantees that without ICSI she wouldn't have had such delays either or that you would have even had any embryos to transfer without ICSI, just like they couldn't guarantee I would have had a miscarriage. I'm sorry to hear of your struggles and I hope you're able to get the support from government health and education programs to get the help she needs.
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#5 poohbear1970

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Posted 05 February 2014 - 01:47 AM

http://www.lifesiten...ren-large-study



#6 JacMac

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Posted 05 February 2014 - 02:52 AM

My thoughts are that I would rather have a child with developmental delays and issues as I could learn to work with those than to not have a child at all. For many couples, certainly some with specific kinds of male factor infertility, ICSI is the only way they can have biological children so now they'll weigh the risks of having such delays against using donor sperm.

Perhaps this type of information wasn't available to the clinic at the time that they were giving you direction towards ICSI. This area of medicine isn't really an exact science and I'm sure information gathering and studies are much more efficient now than they were 8 years ago.
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Me - now 36 Him - 37
Trying to conceive since our wedding day May 25, 2008.
Started Clomid Jan-April 2012.
Referred to RFP June 2012.
First consult at RFP November 2012.
First IVF cycle on antagonist protocol (GonalF, Luveris) January 2013.
Transferred two day-3 embryos, had severe OHSS, lost one twin between 7-13 weeks but was expecting one little one October 2013.
Found out at 6 mos that our little one had died weeks earlier and had to induce and deliver stillborn, July 25, 2013.
Something found on adrenal gland at follow up ultrasound, MRI showed what seems to be a benign tumor. Meeting with specialist Jan 8, 2014 - all fertility treatments on hold. :/
Tumour is definitely producing Aldosterone (causes high blood pressure) and Cortisol. Lucky me, only 34 similar cases recorded in the world! Tumour removed May 2014.
Approached about a possible adoption March 2014. Rush through all the paperwork and process.
Charlotte Evangeline born June 27, 2014. We brought her home on July 7 and held our breath for 10 days until she officially became ours.
Surprise BFP October 2014. Due to wonky cycles, ultrasounds convince Doctors I have a blighted ovum but detailed ultrasound reveals heartbeat at 6w3d. On progesterone support and waiting to see if pregnancy is still viable. Holding our breath again.
Adalyn Marie born on June 9, 2014 after a roller coaster pregnancy.

#7 mouse

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Posted 05 February 2014 - 03:12 AM

All of the studies mentioned in your link are post the time of your daughter's birth so these risks may not have been known to your clinic. Fortunately, as the article linked states, the numbers of affected are small. Another thing to consider is that it may be underlying issues with the sperm, egg, or sperm/egg combination (which also play out in difficulty in becoming pregnant without assistance) rather than the icsi procedure itself leading to at least some of the negative outcomes noted. Umbrellas are frequently seen when it rains but they don't cause rain.


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#8 quandry

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Posted 05 February 2014 - 09:00 AM

It seems as if you are angry poohbear. I suggest finding a good therapist to help. It makes a big difference. Good luck.
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#9 Pandabear8

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Posted 05 February 2014 - 12:36 PM

We got a handout from the clinic regarding potential issues with ICSI children, however in discussing with our RE she said these issues are seen mostly in cases where there is severe male factor issues and therefore ICSI is needed. She said when severe male factor issues are the cause of why pregnancy cannot be achieved naturally, there may be other genetic issues with the sperm and hence those issues are passed on to the child and could manifest itself in some type of disability and/or developmental delay.
It is not directly related to the ICSI procedure itself, but some studies may not include reason of use of ICSI so would generalize results.

In our case we had to use ICSI as sperm was retrieved through PESA due to vasectomy - and our RE said that although she cannot guarantee there wouldn't be any issues, we were not directly affected by the ICSI handout as we were not dealing with severe male factor.

I am not sure what the reason was for use of ICSI in your case, but like everyone else says - there are so many things that go into the mix - genetics, egg quality, sperm quality etc, that you can't lay blame on one thing when it could be one of many things causing issues.
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#10 Red Wine

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Posted 05 February 2014 - 04:23 PM

At our clinic we recieved a consent form for IVF and a separate consent form for ICSI, which I'm sure your clinic provided back in 2006. Basically, the consent says the risks on the form and also that there may be unknown risks that have not been discovered yet. Therefore, I find it very challenging to believe your clinic did not provide you with that information. The clinic would not have performed ICSI on your eggs without your prior written consent and knowledge. 

 

Every medical procedure that a doctor performs requires your consent (unless you are physically unable to give a consent because you've been in a severe accident and are unconscious). All consent forms basically say that anything could go wrong and by signing that form you are accepting the risks a procedure involves. Overall, you may not remember signing an ICSI form, but I bet your clinic could produce your form unless your file has been destroyed because you were at the clinic in 2006.

 

Overall, life is full of known and unknown risks. Making babies naturally or with ART has risks and those risks may not be known until years later. I think if you would have conceived naturally you may still have had a child with a disability.

 

I hope you can find the resources to help your child. Best of luck.


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