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Looking for RPL specialist in GTA

rpl repeated pregnancy loss 40+ miscarriage

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7 replies to this topic

#1 Pat9

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Posted 22 September 2013 - 09:05 AM

Hi everyone,

 

Does anyone know of a specialist here in the GTA that specializes in helping women with repeated pregnancy losses? I have had 5 losses. The pattern appears to be at the 6-7 week mark. 

 

Any suggestions are welcome.

 

Thank you all.

 

Pat


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#2 GraceM

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Posted 22 September 2013 - 09:31 AM

Dr. Virro at Markham Fertility and Dr. Laskin at Lifequest (http://www.itstime.c...vices-term.html).  Dr Laskin is also a physician at Mt. Sinai. 

 

I know some people on the board do not have a good view of Dr. Laskin because there are certain tests/therapies he does not incorporate in his practice but a good friend of mine went on to have a successful pregnancy after 4 successive losses (at "an advanced maternal age") thanks to Dr. Laskin.  She speaks very, very highly of him.

 

I would suggest getting a few opinions anyway to save time and maximize the testing/information you receive.

 

Best wishes.



#3 SummerRain

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Posted 22 September 2013 - 09:50 AM

I'd like to ask the same question. Pat, I have the same problem as you and the only reason the doctor can say is 'advanced maternal age' which is very discouraging since I can't get any younger as time goes by :(

TTC from Aug 2011
DX: advanced maternal age & high DNA fragmentation

Nov 2011: Natural - Chemical pregnancy
Jun 2012: Superovulation - BFP; No heartbeat at 8 weeks, miscarried naturally
Sep 2012: Natural - Ectopic and Methotrexate shot

Mar 2013: IVF#1 - 10 eggs retrieved, 7 matured, 5 fertilized; 2 blastocysts (3BB & 2AB) transferred, 1 blastocyst (2BB) frozen - BFN
Jun 2013: Superovulation - BFN
Jul 2013: Natural - BFP; No heartbeat at 9 weeks, D & C


#4 gibasgirl

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Posted 22 September 2013 - 10:04 AM

Dr. Virro. Markham Fertility Clinic.

The average wait for him is 9 months. See if you can get on his cancellation list. He is thorough and will give you his honest opinion about a situation.

He treats immunological issues which are often the root cause of RPL.

#5 Adventure

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Posted 25 September 2013 - 04:09 PM

Hi Pat.

 

Our journeys are similar. I started the IVF journey at 38 and at that time had had 3 miscarriages from "natural" pregnancies all around 5-7 weeks (I hate using the word natural btw, it seems to imply that IVF is unnatural but I have not better word for it at the moment).

 

When I started the IVF journey at 38  I did the basic immunological testing with my RE and all came back normal. I went on to do one IVF and one FET and miscarried both around 6.5 weeks . I then went to see Dr Laskin and he said all seemed normal and was probably due to advanced maternal age despite my fantastic ovarian reserve (which my RE repeatedly tells me.) My RE agreed re: Laskin's diagnosis so we decided to do PGD on our second IVF to see if that was the cause. Out of 6 embryos that made it to blast, all were basically abnormal.

 

At the time I really struggled with the decision to do PGD as it was really pricey but now I am glad I did it. I don't think this means that I don't have immune issues relating to my RPL but at least I know that all those miscarriages were likely due to advanced maternal age, which I refused to believe at the time. I feel like the PGD provided some answers to part of the puzzle. I'm still contemplating getting a second opinion about RPL from a specialist and will likely pursue it.

 

Have you thought about doing PGD with your next cycle?


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#6 mcbee

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Posted 25 September 2013 - 07:10 PM

I thought I'd add my two senses in here about PGD.....I'm currently awaiting my FET cycle post fresh IVF in August in which I did PGD.  I'm soooo happy I did.  I'm almost 39, so despite 'outstanding' ovarian reserve numbers (as per my doc), egg quality definitely was a concern.  In my fresh cycle, 20 eggs were retrieved, 18 were mature, 13 fertilized via icsi and 7 made it to blastocysts.  All of the blasts were biopse for pgd and then frozen.  Of the 7, 5 were abnormal and 2 were normal.  Despite my age, and my 2 previous loss (I've had one miscarriage, one late term loss at 22 weeks and one live birth, my daughter Brooklyn at 39 weeks), my doctor is recommending transfering only one.  

 

I'm thrilled we did PGD as I *know* I have two healthy, good quality blasts frozen and waiting for me.  I have 2 cracks at it and I feel very confident one of my FET cycles will be successful.  

 

Despite the extra cost (all in, it was about 7K....3K to build the tests and 4K to test my blasts) I'm certain it was the right choice for us.

 

Good luck with whatever you decide!!

 

:) sarah


Me: 39

DH: 34

Together since 2001

 

Dec 2008  - bfp!

Feb 2009 - missed miscarriage detected at 11wsad.png

Feb 2010 - bfp!

June 20, 2010 - severe brain damage detected

June 29, 2010 - DS Ryder was born at 21w5d, weighing 1lb, Passed away after 3 hours in my arms.  sad.png

September 2010 - bfp!

October 2010 - autopsy and genetic testing confirm Ryder's brain damage was passed on by me, as I am a genetic carrier for the L1- Cam mutation (X-linked hydrochephalus).  Has 25% chance in every pregnancy of occuringsad.png

November 2010 - CVS performed, confirmed healthy pregancybiggrin.png

May 5, 2011 - DD Brooklyn was bornbiggrin.png

IVF #1 (planned freeze all)

Aug 2012 - begin IVF journey in order to do PGD to avoid losing another baby to the genetic disorder.

June 2013 - PGD test is finally built and ready to go!

Aug 4 - 300iu Puregon started

Aug 8 - bloodwork/ultrasound, 25 mg ganirelex added, 20+ follicles growing

Aug 10 - bloodwork/ultraound

Aug 12 - bloodwork/ultrasound, puregon reduced to 200iu

Aug 13 - bloodwork/ultrasound, 7 follicles at 17mm+, 10 more close behind.  HCG trigger tonight!

Aug 14 - final bloodwork

Aug 15 - ER, ICSI....20 eggs, 18 mature.

Aug 17 - 13 fertilized, all perfectly on track.

Aug 20 - 7 made it to blastocyst and were biopsed, sent for PGD.  Praying for some to be unaffected!

Sep 3 - PGD report 2 unaffected healthy embryos!!  All systems go for SET on next AF.

FET #1

Sept 27 - start estrace and baby aspirin

Oct 8 - lining check ultrasound, lining 0.9 but a tiny amount of fluid

Oct 10 - lining check ultrasound, lining 0.94 but fluid still present, start progesterone

Oct 15 - third lining check ultrasound, lining 1.2, fluid is gone!

Oct 16 - transfer day!

Oct 22 - bfp at home!!

Oct 25 - 1st beta 85

Oct 28 - 2nd beta 524

Nov 14 - 1st ultrasound...One baby measured 7w2d with a heartbeat of 145.  Such a relief!!!

Dec 16 - genetic counselor called with results of bloodwork....its a girl!!  No chance of the genetic disorder

Dec 20 - NT scan, baby looks great, measured 12w4d 

Feb 4 - next milestone, anatomy scan!

 


#7 SummerRain

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Posted 25 September 2013 - 07:35 PM

Hi Pat.

 

Our journeys are similar. I started the IVF journey at 38 and at that time had had 3 miscarriages from "natural" pregnancies all around 5-7 weeks (I hate using the word natural btw, it seems to imply that IVF is unnatural but I have not better word for it at the moment).

 

When I started the IVF journey at 38  I did the basic immunological testing with my RE and all came back normal. I went on to do one IVF and one FET and miscarried both around 6.5 weeks . I then went to see Dr Laskin and he said all seemed normal and was probably due to advanced maternal age despite my fantastic ovarian reserve (which my RE repeatedly tells me.) My RE agreed re: Laskin's diagnosis so we decided to do PGD on our second IVF to see if that was the cause. Out of 6 embryos that made it to blast, all were basically abnormal.

 

At the time I really struggled with the decision to do PGD as it was really pricey but now I am glad I did it. I don't think this means that I don't have immune issues relating to my RPL but at least I know that all those miscarriages were likely due to advanced maternal age, which I refused to believe at the time. I feel like the PGD provided some answers to part of the puzzle. I'm still contemplating getting a second opinion about RPL from a specialist and will likely pursue it.

 

Have you thought about doing PGD with your next cycle?

 

Hi Adventure,

 

Does that mean you spent about $17k but at the end, nothing to transfer? That's what I fear. It's like spending $17k just for a diagnosis. Sometimes, I feel I'd rather let God to determine the fate of my baby instead of someone in the lab. But the cons with this is too many miscarriages and I feel my body can't take it and it's a waste of time...


TTC from Aug 2011
DX: advanced maternal age & high DNA fragmentation

Nov 2011: Natural - Chemical pregnancy
Jun 2012: Superovulation - BFP; No heartbeat at 8 weeks, miscarried naturally
Sep 2012: Natural - Ectopic and Methotrexate shot

Mar 2013: IVF#1 - 10 eggs retrieved, 7 matured, 5 fertilized; 2 blastocysts (3BB & 2AB) transferred, 1 blastocyst (2BB) frozen - BFN
Jun 2013: Superovulation - BFN
Jul 2013: Natural - BFP; No heartbeat at 9 weeks, D & C


#8 Adventure

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Posted 26 September 2013 - 01:46 PM

Hi SummerRain.

 

The IVF was somewhere around $7k and the PGD was ~ $2500 i think. You are right, I spent all that and had nothing to transfer. But for me it was important to know if it was really an egg issue or if it was something else.

 

I still would have spend the $7K had I not done the PGD but then would have frozen 6 embryos that made it to blast despite being abnormal (so there is cost for that too.) Then I would have transferred 2 embryos at a time, only to miscarry them all and possibly have several D&C, which as you know aren't without risk. I agree with you, at least at my age I didn't have the time to spare and I couldn't continue to do the same thing (IVF) and expect a different outcome. It just didn't make sense to me.

 

I do however also think that each IVF is just a snapshot of your egg quality. Maybe if I try again, I'll get one healthy one, who knows? It's a gamble... 







Also tagged with one or more of these keywords: rpl, repeated pregnancy loss, 40+, miscarriage