So I'm new to this forum, but the optimism and support offered here has made me want to join. I've been diagnosed with PCOS plus a bleeding disorder. My RE essentially thought this would be a basic IUI and we would have a great chance of success as I'm only 26.
Well... I'm on day 33 of this cycle. I've been on Puregon injections since day 1. I'm up to 150 units of Puregon daily, and my Estrogen levels will just not rise. They are sitting at around 180 and rise and fall it seems depending on the weather. So far the highest they have risen is 220, however 2 days after, they have again fallen to 160. My Re says they should get to around 1000. My follicles remain below 10mm.
Has anyone else experienced this type of extremely long cycle? Needless to say, emotionally, I've about had it with monitoring every other day with continued bad news and the RNs at the clinic saying 'wow... still nothing???'. I'm exhausted & frustrated, and the RE says to continue to day 40, then potentially cancel.
Has anyone had the same issue with your Estrogen levels refusing to rise? If you have had a cycle cancelled do to this, did it work the second time?
Any help would be very much appreciated as I'm trying to stay positive, however I seem to be an oddity.
Thanks,
Adele
Me: 27 DH: 29
February 2013- IUI #1
Ended w/ 166 Puregon & microdose of hCG
45 Cycle Days but finally one good follie!
IUI April 4, 2013
... BFN April 18th.
April 26 - IUI #2
No AF after 25po, Docs don't know why, but lining is thin again so switching to Menopur.
75 > 112.5 > 150 > 187.5 > 225 > 263.5 of Menopur > 263.5 of Menopur & 200 of Puregon
CD 30- Cancelled my cycle, but then call me and estrogen surges. Cycle back on.
CD 32- 8 follicles
CD 33- 19 follicles... Surprise! Switching to IVF?!! Add in Orgalutron.
CD 36- 29 follicles and so sore... Trigger shot.
June 1- Retrieval- Sedation didn't work and went through the most painful hour of my life. Left ovary blocked by bowel, so only right retrieved. OHSS... 8 Eggs, 6 mature- ICSI for all 6.
June 4- Transfer 2 Grade 4 embryos, 4 frozen (3 Grade 4s and 1 Grade 3) More OHSS.
... BFN June 15th
July 26- FET #1
After a 6 week break, my body is somewhat back to normal.
4 > 6 > 8 > 16mg of Estrace
CD 16 - Add in Endometrin x3 Daily
August 15 Trasfer- 2 Embryos; One Grade 4 Morula & a 3-Cell Grade 4 (most cells died in the thaw)
... BFN August 26th AF finally arrived after 2.5 years!
September 3 - FET #2
12 mg of Estrace and began Acupuncture
CD 18- Finally @ 8mm begin Progesterone
CD 23- Transfer day- 1 Morula & a 3 cell! Acupunture before and after.
... BFN October 7th
Clinic approves us for a gestational carrier in late November!
December - February Medical and pysch testing and approvals
March- Finished legal
April 9, 2014 - IVF (Gestational Carrier)
GC- CD 1: Starts on Superfact and BC
Me- CD 3: 75 Puregon and 75 Menopur
CD 8: Me 100 Puregon and 75 Menopur, GC starts Estrace
CD 22: Me 250 Puregon, 75 Menopur, x2 Orgalutron - 22 Follicles!
April 28- Egg Retrieval, GC starts Progesterone - 14 Retrieved. 11 Mature and 11 Fertilized.
April 30- Down to 9 embryos and decide to grow to Day 5
May 2- Transferred one 4BB blastocyst into our Surrogate. 5 more growing to blasts (until Day 6)
May 3- 4 of the 5 Embryos arrested.... only 1 left to freeze (3BC)
... BFN... again. May 15th
May 21st- WTF appointment and next steps.