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Number of embys transfered

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#1 manitobamama

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Posted 20 October 2010 - 08:23 PM

My dr has suggested I do a 1 emby transfer at 5 days instead of 2 at 3 days.
He stated it would reduce my risk of twins and would be just a likely to produce a positive result for me. He also said they do this with patients who have a good chance at IVF and that it is the new way of doing things.
Any thoughts?

#2 Lilygirl2727

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Posted 20 October 2010 - 08:56 PM

I have had 4 BFP IVF cycles. One of them, I transferred 3 embryos and ended up with twins when 2 of them implanted. One of them I transferred 2 embryos and ended up with identical twins when one of them implanted and divided into 2. (I later miscarried them.) The other two, I transferred 2 embryos and only one implanted so I had singleton pregnancies. So, basically twins are a possibility no matter how many you implant. And I have never understood why they say your chances are just as good with one embryo instead of 2. With my singleton BFP's, what if I had transferred only one embryo, and that one was the one that didn't make it. I wouldn't have gotten pregnant. But because I transferred 2, I found success because I had double the chance.
So basically, yes, transferring 2 does increase your chance of twins obviously. But I don't agree that transferring one gives you the same odds as transferring 2. If I were you, I would just weigh the pros and cons. I am pregnant with twins now and on bedrest, and I will is rough. Much rougher than I thought it would be. But I wouldn't go back and change things if I could. If you are okay with having twins, and your doc says there is no medical reason why you shouldn't have twins, I would transfer 2 if I were you. But its up to you and whatever feels right for you and your DH.

My age: 38
DH's age: 48

DH: Firefighter

We have 2 children and are also raising my 7 year old nephew.

6 previous ectopics before moving to IVF

IVF#2 Novermber 2005: BFP..... DD Ily Scarlet born 7-23-06
FET#4 July 2007: BFN
IVF#3 Jan 2008: BFP.....DS Cooper Lawson born 10-2-08
FET#5: May 2009: BFP......chemical pregnancy
IVF#4 September 2009: BFP.......identical twins m/c at 12w3d

Anxiously awaiting the start of my first normal period after miscarriage......

1/9/10 AF finally arrived! Hysterosonogram and mock transfer next week.
FET#6 next month
1-28-10 Hysterosonogram normal...waiting to start AF to begin FET cycle

Decided to postpone cycle due to too much stress in my life.

March 7, 2010 AF arrived.....Estrace begins. Transfer on March 26th!

3/26/10 3 beautiful expanding frozen blasts transferred
3/29/10 BFP on a First Response Early Result
3/31/10 HPT's getting darker!

4/5/10 Beta back: 1072 @ 10dp5dt
4/12/10 Beta back: 15700 @ 17dp5dt....u/s on April 19th..hoping to find at least one healthy baby!
4/19/10 U/S shows Twins!! Fraternal....heartbeats measuring 113 and 117
7/02/10 It's a Boy and a Girl! Uterus measuring 4 weeks ahead
9/22/10 28w3d along! Aylish Rose weighs 2lbs 5 oz, Sawyer weighs 2 lb, 13 oz.
10/08/10 30w5d...babies both weigh 3 1/2 pounds....cervix soft and short a 1.6, but closed. On strict bedrest til babies come!
10/21/10 32w4d...Cervix down to 1 cm and 1 cm dilated. On Procardia to keep contrax away and remaining on bedrest.
11/10/10 C/S tomorrow! So excited to meet the babies!
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#3 Emily81

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Posted 20 October 2010 - 10:19 PM

My RE would have prefered for me to have transferred 1(SET) but I chose to transfer 2 on Day 3, mostly b/c even if I got pg with twins I would never regret the decision to transfer 2. However if I transferred one and didn't get pg I would regret not transferring two. Personally I would opt for two even at 5days..Another thing I considered is that the odds for fresh cycles are ALOT higher than frozen cycles, so I preferred to have them transferred rather than frozen. I personally didn't have any to freeze anyway, just the 2 we transferred. Good luck with your decision and your cycle!

Me: 31, DH:34
? Mild PCOS/ Mild Male factor- Low Morph- 9%
TTC- Since Dec 2005

August/Sept 2009- IUI + injectabes cycle- BFN- was converted from IUI to IVF(20 follies growing) and then back to IUI(3 mature follies)....

IVF/ICSI cycle Sept/Oct 2010- BFP- (I insisisted on ICSI against my Drs wishes, and in the end we needed it)..
Oct 12- ER- 19 eggs, 15 mature, 6 fert
Oct 15- ET- morula- 18/20 & a 10 cell- 19/20 (Faith & Wish)
- OHSS starts 8dp3dt- Early beta in ER-636- 12dp3dt, #2- 4,267- 17dp3dt
Nov 23- 8 week u/s- TWINS
Incompetent Cervix diagnosed at 24 weeks. Hospital bedrest 24- 33 weeks due to 0.6 cm cervix, 1-2 cms dialated(at 24 weeks)
May 16th- 2011- Baby A breaks his water
May 18th- 2011- Boys arrive 33w1d
Baby A- CM- 4 lbs 4 oz, 17.5 in, 3:01 PM Baby B- CL- 4 lbs 2 oz, 16.5 in, 3:55 PM Lilypie Kids Birthday tickers

#4 feydruss

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Posted 20 October 2010 - 10:23 PM

I think a lot of doctors are trying eSET with blasts because the rates of success can be higher without the complications of a twin pregnancy. Most REs generally want to avoid twin pregnancies, believe it or not, because of the risks involved. And eSET is very common (if not the actual LAW) in many European countries. That said, it's really a personal decision here. It all depends on what you have to work with.

We did a single blast transfer for our first cycle, and had a brief chemical pregnancy. I would have been okay with transferring two, but at the time my DH was convinced that a single transfer would work, and he was deathly afraid of having twins. He really didn't think he could be an adequate parents to two babies at once. We were told that the rate of success for 2xDay3 would be the same as 1xDay5, so he was relieved that we could go to Day 5 without risking twins.

For our next cycle we transferred two frozen blasts, BFN.

We knew going into our third cycle (second fresh) that we would transfer two if given the opportunity, but we didn't know what day it would be (ended up being Day 3, and we thought it was game over). We did end up with twins from that double transfer, which we really didn't expect (though we knew it was a possibility). At that point we were still honestly expecting another BFN.

I think what happens is that every cycle that doesn't work, you try to up the ante with the next one. Unfortunately you really have to play it by ear, and you won't know until the day after your retrieval what you're possibly dealing with. As it is, we are anticipating the two children we wanted for our family, and still have three good blasts sitting in the freezer. You just never know.

I would suggest that you and your DH sit down and really discuss how you would deal with the possibility of twins, and how many cycles you are willing/able to do if the first cycle fails. We decided to do a single blast transfer partly because of DH's fears, and partly because we knew we were financially able to continue cycling if it didn't work. These are all considerations...

3rd cycle was the charm (despite everything going wrong)!
History and details in my profile
Twin boys Milan and Duncan born at 32w4d on 15 November 2010

#5 LisainSK

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Posted 21 October 2010 - 07:07 AM


My DH and I have largely put this argument behind us for now...our first transfer is on November 1st. But we truly agonized over this decision. We are not at all comfortable with the gestation of twins. The risks terrify me. So we have chosen to undergo eSET. But we are fraught with anxiety of the decision. However we are comfortable and financially able to spread out the chances of a singleton pregnancy over two separate transfers if need be which drastically lessens the chances of a twins gestation (a singleton embie could still split into an identical twin pg but that's out of our control). We will be absolutely devastated if we get a BFN but our chances over two transfers is excellent so we have to look at the flip side of this.

Good luck with what ever you decide. I never thought the decision would be so tough.
Me (33) and DH (35)....married 10 years (small town sweethearts)

December 2006: TTC # 1
May 2007: DH S/A...normal.
September 2007: BFP au naturelle...holy smokes!
November 2007: M/C # 1 @ 12 wk. DNC reveals a Partial Molar Pregnancy.
January 2009: Referral to local OB/GYN
April 2009: Dx Unexplained. Referral to Calgary RFP.
May 2009: Clomid Cycle # 1...BFN
June 2009: IUI # 1 w/ Clomid # 2 and HCG...BFN
July 2009: Clomid Cycle # 3...BFP! Happy but terrified of another m/c.
September 2009: Worst fears confirmed...M/C # 2 @ 8 weeks
October 2009: IVF Orientation at Calgary RFP and on wait list.
January 2010: Dx (Me) Abnormal Karyotype (Pericentric Inversion Chromosome 16)
March 2010: RFP Referral/Consultation with Reprogenetics in New Jersey
March/April 2010: PGD/IVF success odds very low...20% estimated "normal embryos" per cycle and a 41% pg rate
May 2010: Consult with Dr. Schoolcraft of Colorado Center for Reproductive Medicine
June 2010: One Day Work Up @ CCRM (Denver, CO)
June 2010: Predicted Low Responder (Low AFC and AMH). Inversion in difficult spot...We're doing Donor Eggs!!
July 2010: Discovery that I am also a carrier of Fragile eggs didn't have a chance.
July 2010: Annonymous Egg Donor chosen through CCRM
August 2010: Mock FET Cycle completed.
DE IVF # 1
September 2010: Donor Eggs retrieved. Blastocysts to undergo PCR genetic screeing.
October 21, 2010: U/S showing 9.9 mm lining with triple stripe; E2 = 1600 and 1397 US units
November 1st, 2010: FET # 1 (Elective Single Embryo Transfer - eSET)
November 10th, 2010: Beta HCG # 1 = 82, P4 = 23.1 US units
November 12th, 2010: Beta HCG # 2 = 186! BFP!!
November 17th, 2010: Beta HCG # 3 = 1461
November 19th, 2010: Beta HCG # 4 = 3740
November 26th, 2010 U/S: hb = 120 bpm, measuring 6w1d, actual gestation is 6w2d since transfer, CRL = 3.8 mm
Dec. 10th, 2010 U/S: hb = 180 bpm, measuring 8w2d - exactly 8w2d since FET, CRL = 1.8 cm
February 18, 2011: Anatomy scan
EDD = July 20th, 2011

June 28th, 2011 @ 3:19 AM MTN: Levi Darrell John born at 36w6d at 6lbs 14oz and 18" long. He is precious beyond measure.

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February 2012: Bye Bye are the reason I got to where I am today. I am forever reached via pm as my email alerts me. Take care all...wishing you all peace in your hearts soon.

#6 Peter



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Posted 21 October 2010 - 02:14 PM

My dr has suggested I do a 1 emby transfer at 5 days instead of 2 at 3 days.

This is good as long as the clinic has excellent results with day 5 embryos

He stated it would reduce my risk of twins


and would be just a likely to produce a positive result for me.

It depends how good their day 5 results are........

He also said they do this with patients who have a good chance at IVF and that it is the new way of doing things.

there is nothing new in day 5 transfers, I was doing them 24 years ago!

Good luck!


Any thoughts?