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antiphospholipid antibodies/lupus antico


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#1 tigger74

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Posted 08 June 2010 - 03:28 AM

Hi there. I have tested positive for both antiphospholipid antibodies and lupus anticoagulant. I don't know my exact numbers. I asked my RE "on a scale 1 - 10 how bad is it?" His answer was "4.3"
He also said I should start taking baby asprin daily and that may be all I need. I have been ttc for 4.5 years now with one miscarriage at 7 weeks (very low betas right from the beginning)
Is there any other treatments I should start now to help implantation? I have my IVF protocol appointment in one week. Are there any questions I should ask him?
Thank you.
Debbie
DH VR Feb 06, TTC immediately
6 IUI's. 3 Injectable cycles, 3 clomid cycles all BFN
one 'natural' bfp. M/C at 7 weeks May 2007
Starting TCM Oct 08

BCP Aug 1
Synarel Aug 15
Stims Aug 29 150 Repronex

#2 Luckypenny

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Posted 08 June 2010 - 11:39 AM

You may want to try re-posting this in the "Ask the RE" section. Dr. Hudson deals with immunological issues.

Baby asprin is good for blood clotting issues (and it depends on how severe the issue is. In some cases heparin, a blood thinner, is used).

Antiphospholipid antibodies sound more like an immune issue, and I'm not sure that baby aspirin would address it. You may want to get a copy of Dr. Alan Beer's book "Is Your Body Baby Friendly?". It covers immune issues such as antiphospholipid antibodies, including recommended treatment. You can get it from Amazon.ca, for less than $30 and it would ship in less than a weeks time.

Good luck!
Me: 35 DH:35
Dx: Unexplained
Started ttc September 2006
November 2007 - Initial consult at LifeQuest
January 2008 - Diagnostic testing.
February 2008 - Test results - No problems with DH. Dr. suspected I had a PCOS variant and that I probably wasn't ovulating. Suggested superovulation (injectibles) with or without IUI
Decided to forgo treatment for the time being and focus on improving my health.
March 2008 - October 2009 - LOTS of alternative therapy. You name it, I tried it!
February 2009 - confirmed via cycle monitoring I was now ovulating and my ovaries both look fine. Officially unexplained IF. Hmmm, now what?
Next Steps: Had initial consult with Dr. Virro at Markham Fertility Centre on October 1, 2009. Hysteroscopy/laproscopy performed on February 5, 2010. Post op appointment on March 8, 2010. Found out one small spot of endo removed from uterus and a very tiny septum resected.
Started BCP on March 31, 2010.
First IVF (first anything!) cycle after.
Last BCP April 20th.
Started stims: April 25 (Puregon - varied from 100iu to 42.5iu, Menopur - 75iu, and orgalutron)
ER date - May 5th.
14 retrieved, 11 mature, 7 fertilized - 4 via IVF, 3 via ICSI
3 days past retrieval - 5 8-cell embryos (3 via IVF, 2 via ICSI), 2 lagging 6-cell embryos (1 via IVF, 1 via ICSI)
ET on May 10, 5day past retrieval - tranferred 1 "superb, could sell it on e-bay" embaby - grade 5AB0! 4 more "lovely" totsicles (2 5day, 2 6day). The ivf embies did better than the icsi embies.
Beta - May 21s: BFP! Beta was 507! Still early days, but we're happy to be pg!
Viability scan - June 11. Baby right on track, heartrate of 140bpm, measuring 7weeks 1day at just over 1cm long. HOWEVER, big cyst in my right ovary. Going back for another u/s in two weeks to monitor the cyst.
U/S to monitor cyst - June 24 - cyst shrank slightly. Baby still measuring on track, 9weeks 1day and just over 2cm long, heartrate of 167bpm
12week u/s - July 12 - cyst had shrank to 2cm. Baby looked like a baby! Moving around and flailing arms and legs. Just over 5.5cm long, heartrate of 160bpm. Nuchal scan and nasal bone both looked good. Doctor's appointment went well.
20 week ultrasound and doctors appointment - baby looks good - its a girl :) Test results from IPS test show a 1 in 20,000 risk of a chromosomal abnormality. Placenta is partially covering cervix, doctor will check again at 32 weeks.
26 week doctors appointment - GD test
30 week doctors appointment - got GD test results, I passed. Baby measuring on track, good strong heartbeat :)
32 week doctors appointment - u/s to check placenta position to see if it has been pulled up from my cervix and also to check baby's size

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#3 tigger74

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Posted 09 June 2010 - 12:52 AM

thanks for the reply. Ya I should have posted it in the other section.... too tired to go over there now lol

These both have to do with blood and so they recommend asprin...Thanks for mentioning that book. After this long I thought i'd heard about all of the ttc books!
DH VR Feb 06, TTC immediately
6 IUI's. 3 Injectable cycles, 3 clomid cycles all BFN
one 'natural' bfp. M/C at 7 weeks May 2007
Starting TCM Oct 08

BCP Aug 1
Synarel Aug 15
Stims Aug 29 150 Repronex

#4 ---

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Posted 30 June 2010 - 08:08 PM

Tigger, I ditto luckypenny's suggestion about purchasing teh Beer's Book. You will understand about immune issues a whole lot better. :)
Stacy