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Second failed FET


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#1 Tryingformybaby

Tryingformybaby
  • Just Hatched
  • 4 posts
  • Dx:Unexplained
  • My Clinic:Shady Grove

Posted 08 November 2021 - 05:25 PM

Just found out my second FET failed. PGT tested, ERA complaint. I was told 85% survived the thaw for the second time. Anyone have this happen? Im 39 - 4 retrievals - has two genetically normal embryos. Devastated doesnt begin to explain. No idea where to from here.

#2 hopefuldadsomeday

hopefuldadsomeday
  • Global 100+
  • 745 posts
  • Dx:Unexplained
  • My Clinic:Olive Fertility

Posted 08 November 2021 - 08:11 PM

@Tryingformybaby Sorry to hear your FET didn't succeed.  I believe even with PGS-testing, success rate is usually about 60-70%, so maybe it's just due to bad luck.  Our clinic ran two new tests for our most recent FET cycle called ALICE and EMMA.  They ran the test during our mock cycle and it turned out my wife had low grade infection (possibly from her C-section?) and she did a course of antibiotics before proceeding with the actual transfer.  Might be worth discussing with your clinic?  Hope your next attempt is successful!

 

https://www.igenomix.../alice-clinics/

 

https://www.igenomix...s/emma-clinics/


March 2016 - Miscarriage #1 (chemical pregnancy)

August 2016 -  Miscarriage #2 (Trisomy-16)

December 2016 - Miscarriage #3 (unknown - suspected chromosomal abnormality)

IVF #1 - Aug 2017 (estrogen priming antagonist protocol) - 9 eggs retrieved, 3 fertilized, 2 blastocysts, only 1 PGS normal embryo 5BB mitoscore 25.1 (frozen)

IVF #2 - Nov 2017 (estrogen priming antagonist protocol - with testosterone priming and growth hormone) - 7 eggs retrieved, 5 fertilized with ICSI, 1 blastocyst PGS-normal 5BB mitoscore 33.12 (frozen)

IVF #3 - Jan 2018 (estrogen priming antagonist protocol with growth hormone) -  4 eggs retrieved, 2 fertilized with ICSI, 1 blastocyst PGS-normal 6BB mitoscore 29.82 (frozen)

FET #1 - March 2018 - cancelled due to thin lining (6.25mm)

FET #1.2 - April 2018 - cancelled due to thin lining again! (4.85mm)

FET #1.3 - June 4, 2018 (lining 7.5mm!) - th_abfn.gif

ERA Aug 2018 - Pre-receptive by 1 day

FET #2 - Sep 18, 2018 (lining 6.9mm) th_abfp.gif  Beta #1: Sep 30, 2018 - 682  Beta #2: Oct 6,2018 - 6656 U/S: Oct 15 - measuring 6w4d (CRL 6.87mm), HR 127bpm! U/S: Oct 25 - measuring 8w1d (CRL 16.69mm), HR 168bpm!  Discharged to midwives!  June 7, 2019: It's a girl!  DD born 7lb 2oz babygirl.gif

FET #3 - Oct 4, 2021 (lining 8.8mm!)  th_abfp.gif  Beta #1: Oct 14, 2021: 415, Beta #2: Oct 21, 2021: 4778 U/S: Nov 1, 2021 - measuring 6w4d, CRL 6.6mm, HR 133bm! U/S: Nov 15, 2021 - measuring 8w6d (CRL: 22.3mm), HR 182bpm!  Discharged to midwives!


#3 Tryingformybaby

Tryingformybaby
  • Just Hatched
  • 4 posts
  • Dx:Unexplained
  • My Clinic:Shady Grove

Posted 08 November 2021 - 08:58 PM

Thanks so much for your reply. Ill ask about it. Hope it works out for your guys soon!

#4 Cotton3

Cotton3
  • Member
  • 98 posts
  • Dx:Male Factor

Posted 09 November 2021 - 08:35 AM

Some REs are guilty of overselling PGS. Mine told me untested embryos have 40% chance, tested 65%.