Thoughts on ERA?
Posted 14 July 2021 - 11:39 AM
Posted 15 July 2021 - 09:56 PM
Anecdotal evidence, ERA was the difference maker for us (but medicated cycle). All our embryos were PGS-tested. Our first FET cycle, transfer was on day 5 and despite a decent lining, resulted in BFN. Did a ERA test and test showed my wife needed an extra day of progesterone. Our second FET cycle, despite thinner lining and using exact same protocol but just 1 extra day of progesterone, and resulted in our DD. My wife currently doing another mock ERA cycle now before we attempt another FET next month.
March 2016 - Miscarriage #1 (chemical pregnancy)
August 2016 - Miscarriage #2 (Trisomy-16)
December 2016 - Miscarriage #3 (unknown - suspected chromosomal abnormality)
IVF #1 - Aug 2017 (estrogen priming antagonist protocol) - 9 eggs retrieved, 3 fertilized, 2 blastocysts, only 1 PGS normal embryo 5BB mitoscore 25.1 (frozen)
IVF #2 - Nov 2017 (estrogen priming antagonist protocol - with testosterone priming and growth hormone) - 7 eggs retrieved, 5 fertilized with ICSI, 1 blastocyst PGS-normal 5BB mitoscore 33.12 (frozen)
IVF #3 - Jan 2018 (estrogen priming antagonist protocol with growth hormone) - 4 eggs retrieved, 2 fertilized with ICSI, 1 blastocyst PGS-normal 6BB mitoscore 29.82 (frozen)
FET #1 - March 2018 - cancelled due to thin lining (6.25mm)
FET #1.2 - April 2018 - cancelled due to thin lining again! (4.85mm)
FET #1.3 - June 4, 2018 (lining 7.5mm!) -
ERA Aug 2018 - Pre-receptive by 1 day
FET #2 - Sep 18, 2018 (lining 6.9mm) Beta #1: Sep 30, 2018 - 682 Beta #2: Oct 6,2018 - 6656 U/S: Oct 15 - measuring 6w4d (CRL 6.87mm), HR 127bpm! U/S: Oct 25 - measuring 8w1d (CRL 16.69mm), HR 168bpm! Discharged to midwives! June 7, 2019: It's a girl! DD born 7lb 2oz
FET #3 - Oct 4, 2021 (lining 8.8mm!) Beta #1: Oct 14, 2021: 415
Posted 17 July 2021 - 05:01 PM
ERA made no difference for me. Transfers at my clinic were usually done on Day 5 but most clinics now changed that to Day 6 anyways.
Posted 05 August 2021 - 12:41 AM
There are mixed results to ERA. So I think that it really depends on who you are talking to.