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ICSI?


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#1 Newtothis11

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Posted 28 September 2020 - 09:01 PM

Im curious to know how many people have used ICSI that DONT have male factor infertility? I think my clinic recommends it to everyone but Im wondering if there really is any benefit if we dont have male factor inferiority?

#2 Misskika007

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Posted 28 September 2020 - 09:36 PM

Hi Newtothis- we didnt have male factor and used ICSI. Our fertilization rates were pretty much 100%. We figured anything that we can do to improve chances, the better. There is a lot of research out there that states ICSI generally improves fertilization rates over standard ivf procedures.

Me: 36, Hub: 36

TTC 4 years

3rd IVF cycle, 3rd FET-  BFP,  due June 1 heart.gif

 


#3 Newtothis11

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Posted 28 September 2020 - 09:44 PM

Misskika - we used it for both of my previous IVF cycles as well and had a very high fertilization rate. We are getting ready to start another cycle in October and I guess Im just wondering if it makes any difference since its quite a chunk of money

#4 TracyFlick

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Posted 29 September 2020 - 09:44 AM

We did it - no male factor - and also had a high fertilization rate. Seems to be the default of my clinic.


January 2017 TTC

March 2017 BFP

April 2017 m/c

July 2017 BFP

August 2017 m/c

Stopped TTC to investigate issue

January 2018 Cycle monitoring; two misdiagnoses regarding fertility issues

August 2018 Septate found / uterine septum removal

November 2018 IVF #1: seven eggs, six mature, six fertilized with ICSI, four embryos, two PGS-tested normal

July 2019 IVF #2: 21 eggs; 17 mature, 13 fertilized with ICSI, seven embryos, five PGS-tested normal

Planning our first FET in fall 2020


#5 FuzzyDust

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Posted 29 September 2020 - 12:30 PM

We also did it for both IVF cycles, with very minor male factor. I think it's just pretty much standard in our clinic.


-----------------------------------------------------------------------------------------------------
Me: 37 DH: 45
I don't produce FSH, so no natural menstrual cycle. DH has reduced morphology.
Summer 2014 IUI (with first husband): cancelled after almost a month of stims due to too many follicles
Time off to divorce, get back on my feet, find a new hubby and get married again 💑
March 2017 IVF#1: ~70 follicles, 13R, 10M, 7F, 3B = 2 PGS Normal (both XY) - no transfer due to ohss
Sept 2017 FET#1: BFP, Beta#1 - 253, Beta#2 - 528, DS born 05/31/2018 👨‍👩‍👦
Dec 2019 FET#2: BFN
Changed clinic, planning March 2020 IVF#2 - postponed due to the pandemic
April 2020 IVF #2: ~30 follicles, 24R, 12M, 8F, 4B = 2XY & 2XX, all normal  heart.gif 
Sept 2020 FET#3: (one of the XX) BFP, Beta#1 - 161, Beta#2 - 519


#6 hopefuldadsomeday

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Posted 02 October 2020 - 01:36 AM

No male factor and we were recommended to do ICSI in our 2nd and 3rd IVF cycle after our first IVF cycle had low fertilization rate.  While it had slightly higher fertilization rate, we still ended up with the same number of embryos in the end with each cycle.


March 2016 - Miscarriage #1 (chemical pregnancy)

August 2016 -  Miscarriage #2 (Trisomy-16)

December 2016 - Miscarriage #3 (unknown - suspected chromosomal abnormality)

IVF #1 - Aug 2017 (estrogen priming antagonist protocol) - 9 eggs retrieved, 3 fertilized, 2 blastocysts, only 1 PGS normal embryo 5BB mitoscore 25.1 (frozen)

IVF #2 - Nov 2017 (estrogen priming antagonist protocol - with testosterone priming and growth hormone) - 7 eggs retrieved, 5 fertilized with ICSI, 1 blastocyst PGS-normal 5BB mitoscore 33.12 (frozen)

IVF #3 - Jan 2018 (estrogen priming antagonist protocol with growth hormone) -  4 eggs retrieved, 2 fertilized with ICSI, 1 blastocyst PGS-normal 6BB mitoscore 29.82 (frozen)

FET #1 - March 2018 - cancelled due to thin lining (6.25mm)

FET #1.2 - April 2018 - cancelled due to thin lining again! (4.85mm)

FET #1.3 - June 4, 2018 (lining 7.5mm!) - th_abfn.gif

ERA Aug 2018 - Pre-receptive by 1 day

FET #2 - Sep 18, 2018 (lining 6.9mm) th_abfp.gif  Beta #1: Sep 30, 2018 - 682  Beta #2: Oct 6,2018 - 6656 U/S: Oct 15 - measuring 6w4d (CRL 6.87mm), HR 127bpm! U/S: Oct 25 - measuring 8w1d (CRL 16.69mm), HR 168bpm!  Discharged to midwives!  June 7, 2019: It's a girl!  DD born 7lb 2oz babygirl.gif


#7 happyfrog

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Posted 25 October 2020 - 09:27 AM

I have never heard of combining IVF with ICSI in case of no male factor. My friends and me were recommended PGS NGS by our clinic, and it worked out. However, it might depend on a clinic and their experiences in treatments.



#8 tsm37

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Posted 30 October 2020 - 08:30 PM

I'm a male, no male factor. Still, I insist to do ICSI and even PICSI on top of it. Our new doctor has no objections, given a history of multiple IVF/FET failures from another clinic. 



#9 DorothyandToto

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Posted 08 November 2020 - 10:10 PM

Sometimes the clinic recommends ICSI if the eggs used will be from someone over 35 because a womans eggs tend to be tougher for sperm to penetrate as a woman ages. We did ICSI on my 42 year old eggs with no male factor. We ended up with two chromosomally normal embryos (one from each cycle) after PGS testing...and one of those embryos is sleeping in his crib right now, so Im a believer.