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October 2020 FET


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#1 CMRivf

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Posted 12 September 2020 - 10:03 PM

Hey All! Just wondering if anybody is cycling now with an October transfer date?

I just did my first Suprefact injection, transfer will be(hopefully) mid-October.

IVF #1:

November 2017 - 23 Follicles, 18 Fertilized, 3 made it to Day 5, FREEZE ALL due to OHSS

FET #1:

January 31, 2018 - Begin Suprefact Nasal Spray(5x/day), baby Aspirin & Folic Acid

March 2, 2018 - Lining Check -> 8.6mm, transfer scheduled for March 8, 2018

March 8, 2018 - Transferred 1 embryo. Continue Prometrium, Estrace, baby Aspirin & Folic Acid

March 16-19, 2018 - HPTs th_abfp.gif 

March 20, 2018 - Beta Test - 115 (according to nurse, they like to see 250-500) Continue with Prometrium, Estrace & Folic Acid. Stop baby Aspirin.

​March 22, 2018 - Beta Test #2 - 332 th_abfp.gif Tentative due date of November 24, 2018. 7 week U/S booked for April 9. Continue Prometrium & Estrace until April 28.

November 27, 2018 - Healthy baby girl born at 10:32am, weighing in at 8lbs 4oz and 22.5" tall.

FET #2:

March 17, 2020 - Canceled due to Covid.

FET #3:

June 15, 2020 - Canceled due to unknown bleeding/cramping at cervix.

FET #4:

PROTOCOL CHANGES: Will switch to estrogen patches as well as vaginal estrogen. During lining check will test progesterone to make sure I haven't ovulated. Requested a ultrasound the morning of the transfer to make sure everything looks okay.

Sept. 12, 2020 - Begin Suprefact injections, baby aspirin and prenatal/DHA.

 

 


#2 returnable

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Posted 14 September 2020 - 10:52 AM

CMRivf I was really hoping to transfer our last embryo in October, but my period is almost two weeks late. I have a feeling I'm entering into the peri-menopausal stage and that's why it is late. Before all this IVF nonsense I used to be like clockwork and returned to that after pregnancy, but now I'm starting to have night sweats and my period is late. We are at the end of our journey, and although I want this next chapter to be positive, in one way or another I just want to move on.

 

I notice that you didn't update your FET #2 in your signature. I assume that it was not successful. Why do you take Suprefact at the beginning of your cycles and hence your cycle is so long? It takes me forever to build my lining, so my timing is always 30+ days from cycle day #1 to transfer.



#3 tsm37

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Posted 16 September 2020 - 08:51 PM

My wife has started her cycle today and this will be our 4th attempt. Transfer will likely be the first week of October. We have one last PGS-tested normal embryo. It's a female day-6 hatched blastocyst. We discussed with our doctor today and the plan this time will be a regular FET. In December 2019, my wife had a regular FET; while the embryos implanted and developed a bit, the cells of the embryos passed out a few weeks after transfer. We still don't know what went wrong. 

 

In August 2020 (yes, last month), our natural FET ended up with an implantation failure and our doctor today said ERA is still not needed at this point. Since my wife was not even pregnant last time and her period just came, our doctor said it's okay to proceed and start a new cycle. We will use a different brand of patches this time, in addition to taking estrace pills. In December 2019, my wife experienced allergy from the patches. This time around, the doctor prescribed us with another brand and he said he will (if needed) prescribe some medications to deal with any potential allergy this time. 

 

Protocol for now is as follows: prenatal vitamins, viagra, and one patch. No progesterone shot yet. Next week, likely two patches + estrace x 3. 

 

For me, I'm not even setting any expectation and just go with the flow. After multiple failed attempts, it's better not to set any expectation. 


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#4 CMRivf

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Posted 17 September 2020 - 08:11 PM

Returnable - sorry to read about your struggles. I hope you get an answer, either way. It can be so frustrating to have no clear path. We chose to cancel our cycle in March(the day before the transfer) due to Covid. A couple of days later the clinic shut down. I actually cycled again in May/June and my cycle was canceled the day of transfer due to unknown bleeding/cramping in my cervix. Ive had some extra testing done and everything has come back normal so hoping this cycle goes well.

My clinics protocol has me start suprefact on day 21 of my cycle(my cycle is 32 days). Ill get another period and then add in the estrogen and such. I think I usually do about 30 days of injections and my transfer is about 6 days after injections stop.

tsm37 - I hope everything goes smoothly for you this cycle and am sorry to read about your wifes previous cycles. Its so frustrating when the doctors cant tell you where or why the cycle went wrong. I will also be doing estrogen patches(for the first time) and suppositories as well.

IVF #1:

November 2017 - 23 Follicles, 18 Fertilized, 3 made it to Day 5, FREEZE ALL due to OHSS

FET #1:

January 31, 2018 - Begin Suprefact Nasal Spray(5x/day), baby Aspirin & Folic Acid

March 2, 2018 - Lining Check -> 8.6mm, transfer scheduled for March 8, 2018

March 8, 2018 - Transferred 1 embryo. Continue Prometrium, Estrace, baby Aspirin & Folic Acid

March 16-19, 2018 - HPTs th_abfp.gif 

March 20, 2018 - Beta Test - 115 (according to nurse, they like to see 250-500) Continue with Prometrium, Estrace & Folic Acid. Stop baby Aspirin.

​March 22, 2018 - Beta Test #2 - 332 th_abfp.gif Tentative due date of November 24, 2018. 7 week U/S booked for April 9. Continue Prometrium & Estrace until April 28.

November 27, 2018 - Healthy baby girl born at 10:32am, weighing in at 8lbs 4oz and 22.5" tall.

FET #2:

March 17, 2020 - Canceled due to Covid.

FET #3:

June 15, 2020 - Canceled due to unknown bleeding/cramping at cervix.

FET #4:

PROTOCOL CHANGES: Will switch to estrogen patches as well as vaginal estrogen. During lining check will test progesterone to make sure I haven't ovulated. Requested a ultrasound the morning of the transfer to make sure everything looks okay.

Sept. 12, 2020 - Begin Suprefact injections, baby aspirin and prenatal/DHA.

 

 


#5 tsm37

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Posted 21 September 2020 - 12:55 PM

Ladies, I just wanted to get your thoughts about this, but I don't want to create a separate thread.

  • My wife has already started another round of FET and taking medications. Transfer will likely happen sometime during the first or second week of October.

 

  • We consulted with another doctor at Cornell Medical in New York City today and explained to him our history and situation and we are considering working with this new doctor if the upcoming FET fails again.

 

  • I certainly understand that all doctors have different views on things. The takeaways from the consultation is that there are still things that my wife and I can do, in addition to what we have already tried in the current clinic. This doctor at Cornell Medical did tell us about ERA, sperm DNA test, and a number of tests. He said if PGS is already done; the uterus is checked; lining was right and results still negative, then it's time to take a deeper dive into other things and consider a different approach. I have to agree with this statement to some degree because the current doctor keeps on telling us that we have tried everything and the current doctor is not suggesting ERA because my wife did get pregnant before but ended up with DNC. I also understand that this potential new doctor has to speak from a business point of view. To me, I'm just having a hard time to continue to try the same things and hoping for a different/positive outcome. 

 

  • This new potential doctor's view is that if the embryos are PGS-tested, then Cornell Medical's approach is to transfer one at a time and not two in hoping for a twin. Again, every doctor has his/her point of view on things but I also understand that my wife's age is another factor. 

My wife and I think that we shouldn't waste the last PGS tested embryo with our current clinic and continue to proceed with the upcoming FET in October. If it again turns out to be unfavorable, then we will make a decision. What would you do? Have you had experience switching doctor? 



#6 FuzzyDust

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Posted 21 September 2020 - 02:14 PM

Hi tsm - congrats on starting  a new cycle! really hoping that it'll be the one for you, and you wouldn't have to worry about answering the question anymore heart.gif

 

I switched clinics after my first IVF. It just didn't feel the same when I went there for my second FET. Half of the stuff were done, I had to wait for over an hour every single time I went for an appointment (I was on time), I didn't feel like the care was any longer personal or comfortable. That transfer never took, and I was almost relieved at the end, as the whole experience just felt "wrong". I never really got any explanation why (it was a PGS-tested embryo, same grading as my first that did result in pregnancy), just "statistically, it happens" response.

 

The new clinic is amazing. The whole IVF experience was so much better (even though it happened in the middle of the whole COVID situation). I'm 37, and they still recommended to only transfer one at a time (especially if doing PGS testing), because realistically the odds of ending up with at least one baby is higher from 2 single transfers than with one double transfer.


-----------------------------------------------------------------------------------------------------
Me: 37 DH: 45
I don't produce FSH, so no natural menstrual cycle. DH has reduced morphology.
Summer 2014 IUI (with first husband): cancelled after almost a month of stims due to too many follicles
Time off to divorce, get back on my feet, find a new hubby and get married again 💑
March 2017 IVF#1: ~70 follicles, 13R, 10M, 7F, 3B = 2 PGS Normal (both XY) - no transfer due to ohss
Sept 2017 FET#1: BFP, Beta#1 - 253, Beta#2 - 528, DS born 05/31/2018 👨‍👩‍👦
Dec 2019 FET#2: BFN
Changed clinic, planning March 2020 IVF#2 - postponed due to the pandemic
April 2020 IVF #2: ~30 follicles, 24R, 12M, 8F, 4B = 2XY & 2XX, all normal  heart.gif 
Sept 2020 FET#3: (one of the XX) BFP, Beta#1 - 161, Beta#2 - 519


#7 Liblikas

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Posted 27 September 2020 - 08:37 AM

Hi everyone - awaiting AF to get started on an FET in Oct after BFN in August with full IVF cycle.
It will be our second attempt at transfering after 2 years TTC and one chemical pregnancy in the spring. I am 39 and DH 40 - anyone has experience to share on how many embryos to unfreeze and transfer? We have 6 frosties awaiting for now. Thanks!

#8 Liblikas

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Posted 27 September 2020 - 08:37 AM

Hi everyone - awaiting AF to get started on an FET in Oct after BFN in August with full IVF cycle.
It will be our second attempt at transfering after 2 years TTC and one chemical pregnancy in the spring. I am 39 and DH 40 - anyone has experience to share on how many embryos to unfreeze and transfer? We have 6 frosties awaiting for now. Thanks!

#9 smiley

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Posted 27 September 2020 - 12:46 PM

Congrats on 6 embies, that's fantastic. I only have 2 and I'm transferring them on October 1. I'm in the September group- the plan was to transfer in September but my body didn't cooperate early enough. But I'm now set for this Thursday. 

 

I think it depends on whether you are comfortable with a multiple pregnancy and also the quality of your embies. Mine are not PGS tested. I have one really good one and one not so good (AA and BB) and my RE recommended transferring both. He doesn't think the BB will take and because I'm 38 I want to give it one shot and be done with it if possible. And if not successful then go back to IVF as soon as I possibly can before my eggs are too "old". 

If yours are PGS tested then you can choose to transfer one knowing that your chances are better.... 


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#10 tsm37

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Posted 27 September 2020 - 08:41 PM

Wife is on target to transfer in the week of October 5th. We're going back to the clinic on Tuesday for another check up. If all goes well, wife will begin taking progesterone shots. Right now, two estrogen patches and my wife is not experiencing any allergy this time likely because they are not generic. Estrace x 3 per day.

 

Smiley: Good luck this coming Thursday!

 

Liblikas: If the embryos are PGS-tested, consider one at a time. However, age is another factor to consider. Best to consult with your doctor. My wife will turn 36 December. We initially had five PGS-tested embryos and lost four already in two tries. In hindsight, we should have transferred one at a time. Our current doctor suggested two. After multiple failed attempts, we consulted with another doctor and explained to him our situation. This potential new doctor suggested one at a time if embryos are PGS-tested. Wife and I only have one PGS-tested embryo left at the current clinic. 


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#11 Liblikas

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Posted 28 September 2020 - 03:05 AM

Thank you both for your responses and encouragements. 

 

I currently live in Estonia where nobody has spoken to us about PGS testing but I will ask.

The doctor recommends to transfer only one as it will only be our first FET and reading you guys, I think this is what we will do. But then the doctor remains vague as per how many to unfreeze and I understand there is a risk they do not make it through another thawing process. Anyone has experience to share? 

 

Smiley: fingers crossed for your transfer on Thursday. 

 

tsm37: good luck with tomorrow's check up - no allergies or side effects is already a great start!



#12 tsm37

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Posted 28 September 2020 - 11:32 AM

Liblikas: your docs recommendation of one makes sense since it will be your first FET. Time is precious; the embryos are precious. Gotta choose what is reasonable in your scenario and consider your risk tolerance. From my wifes experience, things that can go wrong will go wrong. I always try to be optimistic about everything in life but when it comes to IVF/FET, I find it better to set a low bar of expectation. Note that PGS testing can be costly, at least in the US where I live. Just a heads up. Good luck and keep us posted.

#13 RosySkies

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Posted 01 October 2020 - 02:18 PM

Hi everyone, I have a transfer scheduled for tomorrow. This will be my third FET after having our son in July 2018. I had a low beta in March then a BFN in June. We have 6 embryos remaining. My RE recommended an endo biopsy/scratch, so I had that done in July. It's supposed to give a small boost to pregnancy rates after two failed transfers. The plan was to do the next transfer the following month but of course I skipped a period. So now I'm doing an October transfer. Hopefully the scratch will still help for this transfer.

 

Best wishes to everyone here, hopefully no more setbacks for you all. Hi again to returnable!

 

Liblikas, for your age group (38-40) when I look at the statitstics for an FET (non-PGS, non-eSET) the live birth rates for a singleton birth are pretty similar. 

 

2018 statistics:

Transfer 1: 29.3% chance of singleton

Transfer 2: 30.0% chance of singleton, 9.3% chance of twins, 0.2% chance of triplets

 

2017 statistics:

Transfer 1: 28.9% chance of singleton, 0.1% chance of twins

Transfer 2: 29.0% chance of singleton, 9.0% chance of twins, 0.1% chance of triplets

 

https://sartcorsonli...sequent-attempt

 

Generally doctors would prefer a singleton pregnancy because a twin pregnancy is higher risk. But the overall chance of having at least one baby from this particular transfer are higher if you transfer 2.

 

My RE did give me the option to transfer 2 this time if I wanted. I chose to do 1 again. First, because we're aiming to have only one more baby, and two, for my age group (<35) the singleton birth rate is higher when transferring only 1 embryo vs 2, so chances of having at least one baby are higher when transferring 2 embryos separately instead of at the same time, and third, that tiny chance of triplets always freaks me out lol!


Me - 33   DH - 35

Started TTC Jun 2013

Diagnosis: Low sperm count & motility

 

IVF #1 - Aug 2017 - Antagonist Protocol

    18 eggs retrieved all mature  ICSI'd 16 eggs → 12 fertilized  10 blastocysts

     froze 9, transferred 1 fresh embryo - BFN

 

FET #1 - Oct 2017 - transferred 1 embryo - BFP!! 

    our son was born July 2018 babyboy.gif

 

FET #2 - Mar 2020 - transferred 1 embryo - chemical (beta = 5)

 

FET #3 - Jun 2020 - transferred 1 embryo - BFN

 

FET #4 - Oct 2020 - transferred 1 embryo - BFN

 


#14 tsm37

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Posted 01 October 2020 - 09:31 PM

Wife is scheduled to transfer on Monday, October 5th. She started progesterone shot two days ago. 



#15 Liblikas

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Posted 02 October 2020 - 06:51 AM

@RosySkies: thanks for the data and your personal experience. I think we will go for one again. Just waiting for AF to get started on treatment and set a date for transfer.

Good luck for yours as well! Maybe we will transfer around the same time.

 

@tsm37: Good luck for Monday - fingers crossed for you guys it all goes smoothly! 



#16 765

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Posted 02 October 2020 - 05:38 PM

Hello just had my first FET yesterday October 1st...
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#17 Liblikas

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Posted 03 October 2020 - 06:57 AM

@765 - congrats! Crossing fingers for you! 



#18 returnable

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Posted 04 October 2020 - 08:23 AM

@RosySkies. I also missed my period in September. Went on BCP for a week and have been spotting, but no full flow. Not sure what is going on.



#19 tsm37

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Posted 05 October 2020 - 01:18 PM

Wife got her transfer today. The 2WW countdown begins. More information to follow.

#20 Liblikas

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Posted 06 October 2020 - 06:21 AM

@tsm37: good luck with the 2WW!

It seems I will get transfer around the 20th. Best of luck to all of you transferring these days.



#21 RosySkies

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Posted 09 October 2020 - 10:31 AM

My transfer was on Oct 2. Transferred a lovely 4AA embryo, the doctor said the transfer went perfect.

 

I'm 7dp5dt today, and I tested with a FRER this morning. BFN

 

So it looks like I'm probably out for this cycle again. Blood test is on Sunday (Oct 11) 

 

This will be my third negative in a row. I'm not sure if it would make sense to do an ERA analysis considering I previously had a successful transfer. Unless pregnancy could've changed my lining somehow. Or maybe I should just cycle again right away, I don't know


  • Caroline2019 likes this

Me - 33   DH - 35

Started TTC Jun 2013

Diagnosis: Low sperm count & motility

 

IVF #1 - Aug 2017 - Antagonist Protocol

    18 eggs retrieved all mature  ICSI'd 16 eggs → 12 fertilized  10 blastocysts

     froze 9, transferred 1 fresh embryo - BFN

 

FET #1 - Oct 2017 - transferred 1 embryo - BFP!! 

    our son was born July 2018 babyboy.gif

 

FET #2 - Mar 2020 - transferred 1 embryo - chemical (beta = 5)

 

FET #3 - Jun 2020 - transferred 1 embryo - BFN

 

FET #4 - Oct 2020 - transferred 1 embryo - BFN

 


#22 Caroline2019

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Posted 09 October 2020 - 05:42 PM

Hello! I had my transfer today! Just wondering if I should be considering acupuncture? Anyone have any tips on what to do after a fet? Thanks!

#23 Caroline2019

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Posted 09 October 2020 - 05:42 PM

My transfer was on Oct 2. Transferred a lovely 4AA embryo, the doctor said the transfer went perfect.
 
I'm 7dp5dt today, and I tested with a FRER this morning. BFN
 
So it looks like I'm probably out for this cycle again. Blood test is on Sunday (Oct 11) 
 
This will be my third negative in a row. I'm not sure if it would make sense to do an ERA analysis considering I previously had a successful transfer. Unless pregnancy could've changed my lining somehow. Or maybe I should just cycle again right away, I don't know


So sorry to hear that! : (

#24 tsm37

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Posted 10 October 2020 - 01:29 PM

duplicated, deleted.



#25 tsm37

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Posted 10 October 2020 - 01:29 PM

I have a bad feeling about this. Day 5 after transfer and my wife has experienced zero symptoms and urine strip did not show any faint line. So, our second implementation failure.

After all the previous failed attempts, I just know that this time will not be good either. Like I said previously, we used our last PGS tested embryo at this clinic and thats it for this doctor. There is absolutely zero chance for us to continue to try the same approach with this doctor and hope to work. We will go ahead and switch to a new doctor whom we already consulted with. Next time, wife will do ERA.