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Embryo grading 3AB


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#1 Mary111

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Posted 11 March 2020 - 12:04 PM

Has anyone had success with embryo 3AB? It is pgs tested but my doctor saying quality is so so..feeling down. Need some reassurance. Should Pgs tested matter more than grading?



#2 cj123

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Posted 11 March 2020 - 02:31 PM

PGS is better than grading!  As long as it is normal it has a chance!  I have heard of people having excellent graded embryos not work and terrible graded ones becoming babies!  


Me - 31  Hubby - 31

 

Trying to conceive since 2012

 

2013- Husband diagnosed with Congenital Absence of Vas Deferens caused by being a carrier for Cystic Fibrosis

 

2013 - decided to adopt before pursuing fertility treatments

 

November 2015 - Our beautiful baby boy is born!  We got to be there for the birth!  He's ours!

 

May 2016 - Adoption Finalized!!!

 

After a cancelled IVF cycle and an IVF cycle that completely failed for unknown reasons (22 eggs, 10 fertilized, zero on day five), we have moved onto donor embryos! 

 

August 2017 - We received three beautiful embryos from an amazing donor family!  

 

FET #1- One beautiful hatching 5 day blast transferred Oct 11/17 - BFP!!! beta #1- 92 (9dp5dt) beta #2- 297 (13dp5dt)

beta #3- 700 (16dp5dt) beta #4- 3500 (20dp5dt)  

Ultrasound Nov 7 (6w4d) - One little bean, heartbeat of 125 bpm!  Due June 29, 2018

June 19, 2018 It's a Boy!! 7 lbs 2 oz of perfection!

 

FET #2 - One day 6 Blast transferred Feb 26/2020 - BFN 

 

One final chance with one final embryo hopefully soon!  Go away Covid-19!

 


#3 Cotton

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Posted 11 March 2020 - 03:18 PM

From what I've read the PGS matters more than grading but even a PGS normal is not 100%.



#4 elephantshoes

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Posted 12 March 2020 - 11:00 AM

That's a super odd comment from your Dr on a PGS tested embryo - is it possible that it didn't thaw/re-expand properly?

 

Anyway, good news...

 

Baby #2 was a 3AB PGS tested embryo and she's now a smart, fiery two year old.

 

Baby #3 was a 3BA PGS tested embryo whom we're hoping to meet in about 20 weeks.

 

In both cases my RE told me that these embryos were about as good as they get :) (although yes, I recognize that AA is the best rating!)

 

Hope this cheers you up!  Good luck!


IVF 1 - cancelled, oversuppressed

IVF 2 - cancelled, ovulated through stims

IVF 3 - BFP, welcomed beautiful baby girl

FET 1 - 1 blast, BFN

FET 2 - 1 blast BFP, chemical

FET 3 - 2 blasts, BFN

IVF 4 - adding in PGS this time, two PERFECT blasts transferred, BFN

ERA revealed implantation window is off by 2 days

IVF 5 - cancelled, ridiculously bad growth compared to other cycles

IVF 6 - transfer cancelled, all 11 blasts came back genetically abnormal

 

getting second opinion/changing clinics...the story continues...

 

IVF 7 - 34 retrieved, 7 day 5 blasts, 6 PGS NORMAL!!!

FET 4 - 1 euploid blast (4BB), BFN

Immune testing - NK cells too high, LADs too low - 3 LITS + IVIG recommended and completed

ERA testing shows that lining is receptive for 7.5dt 

FET 5 - 1 euploid blast (3ABO), BFP

BETA #1 - 10dp5dt 252

BETA #2 - 12dp5dt 559

everything is crossed...

Welcomed another beautiful baby girl 

 

FET 6 - 1 euploid blast (3BAO), BFP

BETA #1 - 13dp5dt 420

Welcomed our 3rd beautiful baby girl

 

Our journey is complete.  What a wild ride.


#5 Tarsette

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Posted 12 March 2020 - 11:15 AM

Can I jump in on this thread with a grading question? I have 8 frozen embryos and none of them have a perfect grading (I have a 5BB, a 4BC, à 3BB, a 5CB, etc.). How do I decide which one is the best one to transfer? Which part is the most important: the number, the first letter or the second letter?

#6 cj123

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Posted 12 March 2020 - 01:56 PM

Tarsette - have you talked to your clinic and how they choose which they transfer first?  My clinic doesn't transfer on grading.  They transfer based on which embryo became a blastocyst the fastest.  So whichever place they got in that race is how they choose to transfer.  


Me - 31  Hubby - 31

 

Trying to conceive since 2012

 

2013- Husband diagnosed with Congenital Absence of Vas Deferens caused by being a carrier for Cystic Fibrosis

 

2013 - decided to adopt before pursuing fertility treatments

 

November 2015 - Our beautiful baby boy is born!  We got to be there for the birth!  He's ours!

 

May 2016 - Adoption Finalized!!!

 

After a cancelled IVF cycle and an IVF cycle that completely failed for unknown reasons (22 eggs, 10 fertilized, zero on day five), we have moved onto donor embryos! 

 

August 2017 - We received three beautiful embryos from an amazing donor family!  

 

FET #1- One beautiful hatching 5 day blast transferred Oct 11/17 - BFP!!! beta #1- 92 (9dp5dt) beta #2- 297 (13dp5dt)

beta #3- 700 (16dp5dt) beta #4- 3500 (20dp5dt)  

Ultrasound Nov 7 (6w4d) - One little bean, heartbeat of 125 bpm!  Due June 29, 2018

June 19, 2018 It's a Boy!! 7 lbs 2 oz of perfection!

 

FET #2 - One day 6 Blast transferred Feb 26/2020 - BFN 

 

One final chance with one final embryo hopefully soon!  Go away Covid-19!

 


#7 Cotton

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Posted 12 March 2020 - 07:16 PM

Tarsette - my clinic didn't ask me. They transferred what they judged to be the best one and I got a BFP with our first FET. None of my embryos had a perfect grade either. Actually I was really surprised at how mixed they were in grading.



#8 Canadamommy2

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Posted 14 March 2020 - 12:10 AM

Im currently 23w with 3BB. I also have 2 failed FETs with 5AA and 6AA that ended up as a blighted ovum. Grading is just a beauty contest sometime ;)
Age : Me 34
Hubby 43

Trying to conceive : 2 years
IUI : 4 failed
IVF#1 : 19 folical, 19 retrieved, 11 fertilized with ICIS
FET#1, #2 : FAILED 😭😭
FET#3 : our Son, Alexander was born November 2015 🎉🎉🎉🎂😍💖

Sibling project is started ^^ 😊😊😊
FET #4 (2017) (Natural FET, estrace day3-7, hcg trigger shot, low does hcg every 3 days after transfer)
Cd3 : lining 4.1Cd9 : lining 7.1Cd10 : lining 8.6 tripple line+trigger shot good to go.
Dec2 : transfered 1 5AA BlastoBeta#1 (9dp5dt) 388 !!!!Beta#2 (12dp5dt) 798 !!!!!!! Im officially PREGNANT !!! ;-)
12w NT SCAN showed 10mm Cystic hygroma(didnt get the result until 15w ;-( ;-( )
NIPT low risk all 3 Trisomy 13, 18, 21
17w1d : Diagonsed with 11m cystic hygroma +hydrops
17w2d : Disgnosed with Hypo plastic right heart syndrome
18w4d : TMFR. Our hearts are shattered. Our little sleeping angel baby girl Cicely Bella Veighey was born @2:30.She was beautiful just like her name. She was so loved and so wanted. Mommy and daddy and your big brother will love you forever !!!Sibling project continue with the hole in our heart.Hoping to

TTC our rainbow baby girl (if possible)
FET#5 : transfered perfect 6AA fully hatched
10dp5dt : 428 Progesterone 60
12dp5dt : 709 (not quite double) progesterone 50
14dp5dt: 1457 Progesterone 49
19dp5dt: 6158 Progesterone ?
7w u/s gestrational sac measure 6w2d no fetal pole or heart beat
10w gestrational sac still the same 6w2d still no fetal pole or heart beat. Diagnosed with Blighted ovum ;( took Misoprostole to end the pregnancy and spotting for 8w until beta turned back to 0.

Continue our sibling Progect. We will bring home our rainbow this time!!

#9 SynchroGirl

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Posted 15 March 2020 - 07:19 AM

I am currently 17w from a 3AB PGS tested embryo. It also busted in 2 when it implanted and became twins! I think 3ABs are great! :)

Me: 40 DH: 52

Dx: Mild Endo, Immune Related Issues, Unexplained

TTC #1 since 2003... 3 years ending in heartbreaking divorce...

Lap #1 in 2005 (mild endo), Lap #2 in 2013 (confirmed no regrowth)

6 IUIs 2013-2014 @ RCC

IVF #1 (March 2018) - 4 eggs retrieved, 1 blast - 3BC (not tested), fresh transfer, BFN

Changed clinics - now @ MFC / Dr Virro - referred for immune testing, Dr wants to first get 2-3 PGS normal embryos before doing immune testing

May 2018-May 2019: 6 more IVF cycles.. 12 embryos, 3 PGS normal (5AB, 3AB, 4BC), 1 mosaic (4BB), 1 too small to test (3BC), 7 abnormal

Immune testing revealed low leukocyte antibodies (1%)

May-June 2019: LIT #1 (x2 treatments) with DH - minor improvement

July-Sept 2019: LIT #2 with donor (x3 treatments) - again minor improvement

Oct-Nov 2019: LIT #3 with new donor (x2 treatments) - not going to wait for the results, proceeding with transfer in December 2019

Dec 20, 2019 - first ever BFP!

 

 


#10 Tarsette

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Posted 16 March 2020 - 10:58 AM

Thanks for your replies! I talked to my doctor today and she said they will transfer a 5BB because, as you were saying Cj123, they actually focus more on the overall progression of the embryo from day 1 to 5 than on the grading itself! So well see! I had a 4AB transferred back in August and it ended in a BPN so hoping this FET will be luckier

#11 IreneT

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Posted 20 March 2020 - 12:11 PM

That seems like an odd thing to say. Did it seem like it was reexpanding properly after thaw? With my son, my clinic was using a different grading system. He was a "grade 3 blast" which I think is something like a 3CC. When he thawed, they upgraded him to a "grade 2 blast" which would be like a 3BB. The last embryo I transferred was a 2BB and I'll be six weeks tomorrow. Ours aren't PGS tested.


IVF#1 (April 2017): retrieved one egg, fresh 3-day transfer, missed miscarriage around 7 weeks, D&C

 

IVF#2 (Sept 2017): retrieved 23 eggs, 22 mature, 18 fertilized, 3 frozen on day 5, no transfer

 

FET#1 (Nov 2017): one grade 3 blast (upgraded to grade 2 at transfer), first β-HCG of 751 at 12dp5dt, delivered my son at 39w6d by unplanned c-section

 

FET#2 (Feb 2020): one grade 2 early blast, first β-HCG of 480 at 11dp5dt. 7w3d ultrasound showed embryo measuring 7w2d with a heart rate of 153. Heart rate at 12w5d: 148, at 16w4d: 147


#12 Tarsette

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Posted 23 March 2020 - 04:57 AM

I had the transfer today and the clinic said it was still the same grading after the thaw, so I am hoping that means it was expanding properly again. I havent had my embryos PGS tested as they were produced from frozen eggs so that would be one thaw and freeze too many for them according to my Dr!