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FET - Missed Estrogen/Break Through Bleeding


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#1 CMRivf

CMRivf
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  • 139 posts
  • Gender:Female
  • Dx:Male Factor
  • My Clinic:Regional Fertility Program

Posted 07 March 2020 - 03:31 PM

Hello! I missed a dose of estrogen yesterday morning (2mg) and today I have break through bleeding. Has anybody else gone through this with a positive outcome or have I messed everything up?? Totally panicking over here while I wait for a call back from my clinic.

IVF #1:

November 2017 - 23 Follicles, 18 Fertilized, 3 made it to Day 5, FREEZE ALL due to OHSS

FET #1:

January 31, 2018 - Begin Suprefact Nasal Spray(5x/day), baby Aspirin & Folic Acid

March 2, 2018 - Lining Check -> 8.6mm, transfer scheduled for March 8, 2018

March 8, 2018 - Transferred 1 embryo. Continue Prometrium, Estrace, baby Aspirin & Folic Acid

March 16-19, 2018 - HPTs th_abfp.gif 

March 20, 2018 - Beta Test - 115 (according to nurse, they like to see 250-500) Continue with Prometrium, Estrace & Folic Acid. Stop baby Aspirin.

​March 22, 2018 - Beta Test #2 - 332 th_abfp.gif Tentative due date of November 24, 2018. 7 week U/S booked for April 9. Continue Prometrium & Estrace until April 28.

November 27, 2018 - Healthy baby girl born at 10:32am, weighing in at 8lbs 4oz and 22.5" tall.

FET #2:

February 12, 2020 - Set to begin Suprefact(injections this time) and baby aspirin. Already taking prenatal vitamin and vitamin D.

Feb. 28, 2020 - Begin 1mg of Estriodal 2x/day, increase to 2mg 2x/day March 3 and 3mg 2x/day March 8.

March 7, 2020 - Break through bleeding. Estriodal increased to 4mg 2x/day.

March 12, 2020 - Ultrasound to check lining thickness--->9mm. Transfer scheduled for March 18. Last Suprefact injection today.

March 13, 2020 - Continue Estriodal, baby aspirin and prenatal. Add in Prometrium(2 pills 3xday) and Doxycycline. 

 


#2 Cotton

Cotton
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Posted 07 March 2020 - 09:37 PM

I missed alot of estrogen. By the time my 12 weeks were up I had half or a third a bottle left. I don't remember if I missed any during the 2ww and I never had bleeding (but I did have a SCH) and my pregnancy is still happily chugging along. I did elect to do daily PIO because I knew I would forget 3x a day doses, maybe that helped.



#3 CMRivf

CMRivf
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  • 139 posts
  • Gender:Female
  • Dx:Male Factor
  • My Clinic:Regional Fertility Program

Posted 09 March 2020 - 09:54 AM

Hi Cotton, I should have been more specific. I haven't had my transfer yet, I go for a lining check on March 12th!

 

I did hear back from my clinic though. They said that the missed dose of estrogen would not have caused the break through bleeding to occur. They upped my estrogen to 4mg 2x/day with the lining check to remain on the 12. 


IVF #1:

November 2017 - 23 Follicles, 18 Fertilized, 3 made it to Day 5, FREEZE ALL due to OHSS

FET #1:

January 31, 2018 - Begin Suprefact Nasal Spray(5x/day), baby Aspirin & Folic Acid

March 2, 2018 - Lining Check -> 8.6mm, transfer scheduled for March 8, 2018

March 8, 2018 - Transferred 1 embryo. Continue Prometrium, Estrace, baby Aspirin & Folic Acid

March 16-19, 2018 - HPTs th_abfp.gif 

March 20, 2018 - Beta Test - 115 (according to nurse, they like to see 250-500) Continue with Prometrium, Estrace & Folic Acid. Stop baby Aspirin.

​March 22, 2018 - Beta Test #2 - 332 th_abfp.gif Tentative due date of November 24, 2018. 7 week U/S booked for April 9. Continue Prometrium & Estrace until April 28.

November 27, 2018 - Healthy baby girl born at 10:32am, weighing in at 8lbs 4oz and 22.5" tall.

FET #2:

February 12, 2020 - Set to begin Suprefact(injections this time) and baby aspirin. Already taking prenatal vitamin and vitamin D.

Feb. 28, 2020 - Begin 1mg of Estriodal 2x/day, increase to 2mg 2x/day March 3 and 3mg 2x/day March 8.

March 7, 2020 - Break through bleeding. Estriodal increased to 4mg 2x/day.

March 12, 2020 - Ultrasound to check lining thickness--->9mm. Transfer scheduled for March 18. Last Suprefact injection today.

March 13, 2020 - Continue Estriodal, baby aspirin and prenatal. Add in Prometrium(2 pills 3xday) and Doxycycline. 

 


#4 yaenaSK

yaenaSK
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  • Gender:Female
  • Dx:Other
  • My Clinic:Aurora

Posted 10 March 2020 - 02:59 PM

Hi there - I missed estrogen doses both in the lead up to, and post transfer this past cycle. I was terrible! I think I missed a dose the day before my lining check and was convinced that was why my lining was a little less thick than before (but it was still fine to go ahead with transfer). And then I missed one dose, maybe two, in the TWW.  In the TWW I ended up taking my missed dose, waiting about 90 minutes, then taking the second - but not sure that was the best option. Currently happily almost 19 weeks pregnant - so it didn't mess up anything for me, thankfully!

 

I found setting my alarm on my cell phone to remind me was big - and then I had to take it immediately when the alarm went off or I would forget.


Me: 38

DH: 43

 

June, July, Aug, Sep 2016: IUI. All BFN.

January 2017: IVF #1. 7 eggs retrieved, 6 fertilized. 1 transferred on day 5 - BFP! DD born 10/08/17. heart.gif (2 embryos frozen)

Nov 2018: FET #1. 1 transferred. Chemical pregnancy.

Dect 2018: FET #2. Last embryo transferred. BFN.

April 2019: IVF #2. 16 eggs retrieved, 11 fertilized. 1 transferred on day 5 (5 frozen). Chemical pregnancy again.

Aug 2019: FET #3. 1 transferred - BFP!  Lost HB at 9 week U/S. MMC.  cry.gif

Nov 2019: FET #4. 1 transferred - BFP again! Hoping this is our strong embryo!