3 replies to this topic

[Kansteo]

Hello, I'm scheduled to undergo my first embryo transfer in a week, and I'm due for a vaccination but I'm concerned about the immune response to the vaccine interfering with implantation.


I tried to get caught up on my vaccines before this point, but I still have my final dose of the Hep A and Hep B vaccines left to go. I'm due to take it this month, but that would mean getting vaccinated either just before or just after embryo transfer. I looked both up, and neither are live attenuated vaccines, and both are considered safe to give pregnant and lactating women. Those pregnant women, however, would typically already have a well-established pregnancy since they wouldn't know they were pregnant otherwise. I'm worried that the normal immune response of learning to recognize Hep A + B might interfere with implantation. Would I be better off waiting a month or so and getting my final dose then? Or am I just worrying over nothing, and I should go ahead and get this tied up before pregnancy?

[Cotton]

Assuming you are not travelling and are not at risk of being exposed, I would wait until the 2nd trimester.

If you are travelling, I would take them ASAP. You can try calling a public health nurse to see if there's any harm in taking them early.

[Kansteo]

Thank you, I think that sounds like a good idea. I won't be travelling, but I have family members with hepatitis, hence my concern. But second trimester seems like a safer bet.

[CdnHockeyGal]

This is a question for your doctor to answer.  In absence of anyone here being an RE with a specialty in immunology no one could possibly give you an appropriate evidenced based answer.