Posted 13 April 2018 - 04:59 PM
Hi Sophia_cop - my wife was on the clinic's standard medicated FET protocol. She started with estrace 2mg three times a day oral, then when she didn't respond, they added estrace vaginally. After that they added estradot patches. We approached our RE about vaginal sildenafil as recommended by Dr. Sher. He said their clinic's experience was it didn't help, but he agreed to prescribe it. We were told to just insert the regular tablets vaginally and my wife found they weren't dissolving well when used vaginally, so we ended up going to a compounding pharmacy to make them as vaginal suppositories. Unfortunately our cycle got cancelled (after 3 weeks her lining still only at 6.2mm and there was fluid buildup) before we got to try them to see if it would have made a difference.
Our current cycle our RE wants to try a natural unmedicated FET, although my wife is contemplating using the vaginal sildenafil suppositories she had made up last time anyways. Her first 2 IVF cycles on trigger day, her lining was also around 6mm, but for some reason her 3rd cycle was 9mm? Not sure if that was due to a measurement error or not.
Please post back with any updates! My wife has been following Dr. Sher's blog for awhile and she was thinking of booking a consult with him if our current FET is canceled again.
March 2016 - Miscarriage #1 (chemical pregnancy)
August 2016 - Miscarriage #2 (Trisomy-16)
December 2016 - Miscarriage #3 (unknown - suspected chromosomal abnormality)
IVF #1 - Aug 2017 (estrogen priming antagonist protocol) - 9 eggs retrieved, 3 fertilized, 2 blastocysts, only 1 PGS normal embryo 5BB mitoscore 25.1 (frozen)
IVF #2 - Nov 2017 (estrogen priming antagonist protocol - with testosterone priming and growth hormone) - 7 eggs retrieved, 5 fertilized with ICSI, 1 blastocyst PGS-normal 5BB mitoscore 33.12 (frozen)
IVF #3 - Jan 2018 (estrogen priming antagonist protocol with growth hormone) - 4 eggs retrieved, 2 fertilized with ICSI, 1 blastocyst PGS-normal 6BB mitoscore 29.82 (frozen)
FET #1 - March 2018 - cancelled due to thin lining (6.25mm)
FET #1.2 - April 2018 - cancelled due to thin lining again! (4.85mm)
FET #1.3 - June 4, 2018 (lining 7.5mm!) -
ERA Aug 2018 - Pre-receptive by 1 day
FET #2 - Sep 18, 2018 (lining 6.9mm) Beta #1: Sep 30, 2018 - 682 Beta #2: Oct 6,2018 - 6656 U/S: Oct 15 - measuring 6w4d (CRL 6.87mm), HR 127bpm! U/S: Oct 25 - measuring 8w1d (CRL 16.69mm), HR 168bpm! Discharged to midwives! June 7, 2019: It's a girl! DD born 7lb 2oz