I am feeling very frustrated as my FET cycle using a GS was just cancelled. The embryo is from a 5x proven donor. I was her 6th donation in a shared cycle. The other half got a baby and I got a twin miscarriage. We are now using frozen blasts from that cycle and moved on to a surrogate.
The GS has 3 children of her own with normal pregnancies. She is 49 years old, extremely healthy and has a regular period every 25-28 days.
Last month, she took estrace for about 10 days and then added progesterone suppositories (and a pill) for five days. After she started the progesterone, she started spotting. We were told not to worry but to stop taking baby aspirin. We did and proceeded to transfer. Result negative.
This month, the exact same thing happened, (spotting starting on the 2nd day of progesterone) and on the day of transfer, it was cancelled with a recommendation of a sono before trying again. Her lining was 12 B which I know is good. Of course I am resorting to Dr. Google and see lots of people proceeding succesfully with spotting and also some cycles getting canceled. What is your take? Thank you.
p.s. on both cycles, she also took medrol, doxycycline, baby asa. The second cycle, she added prednisone and did intralipids (what a waste).
TTC #1 since 04/06
Age: 45, DH: 51. TTC#1 since 04/06
2/07 First Clomid natural cycle = BFN
3/07 Second Clomid natural cycle = BFP, MC 5/07 at 8 weeks, D & C 5/07
07/07 Third clomid natural cycle= no sign of follicle but ovulation assumed by bloodwork = BFN
8/07 First Clomid + IUI cycle = BFN + complications
9/07-11/07 Unable to TTC due to recovering from injury
12/07 First Injectibles cycle (SC) (Puregon) + IUI = 1 mature follicle and a BFN
01/08 2nd Injectibles cycle (IM)(Puregon & Repronex), 2 follicles but not quite mature, IUI any way = BFN
02/08 3rd injectibles (IM) (Bravelle & Repronex), 2 follicles 21 and 14, IUI = BFN
03/08 4th injectibles (IM) (Clomid + Gonal F), 1 follicle, IUI x 4 days in a row = BFN
04/08 IVF#1 Lupron flare w/o BCP, Lupron+Bravelle+Repronex, 7 follies but only 1 matures +IUI=BFN
05/08 Break from injectibles: Femara + IUI = BFN
06/08 Break from injectibles: Femara + 1 follicle + IUI = BFN
07/08 6th injectibles: high dose gonal F: 1 follicle +IUI =BFN
08/08 IVF#2 with low dose repronex only: Surprise 3 follies, 15, 19, 21. 1 egg retrieved fertilized and Grade 1 8 cell transfered aug 19=BFN
BREAK of 6 months turned to 8: took accupuncture, lost 30 pounds, added exercise, turned 41, Day 3 FSH
down from average 7 to 4, worked on marriage relationship strained from dealing with IF
05/09 IVF #3 Gonal F and menopur. 5 Follicles but none mature. Cycle canceled.
07/09 IVF #4 Known DE cycle, 10 follicles, 1 sad egg, no fertilization. WT*?
08/09 Started taking DHEA (why didn't I know of this before?)
01/10 IVF #5: Convert monitoring cycle to natural cycle IVF due to 2 mature follicles being observed on ultrasound
01/10 1 grade 1, 8 cell embryo transferred. BFN
04/10 Estrogen Priming Cycle was cancelled for some reason I forget. known DE planned
08/10 IVF #6 Estrogen Priming Cycle with massive doses of FSH
= nothing = cycle canceled and told to go away.
09/10 Waiting for Known DE cycle with younger donor
12/10 Known DE backs out
02/11 IVF #7. 2 embryos, both transferred. HPT+ 8dp3dt!!!, Beta #1 14dp3dt 278, Beta #2 16dp3dt 604, Beta #3 18dp3dt 1158 (not quite doubled...), first ultrasound--> TWINS!! March 25 only one slow heartbeat. April 2 no growth, slow heartbeat, April 6 no heartbeats--miscarriage at 9 weeks. D&C.
9/11 IVF #8 Sad looking embryos. 4 transferred on day 3. BFN. Advised to move onto surrogacy. d e v a s t a t e d and b r o k e
04/13 Adopted 2 blastocycsts: BFN. Sperm banked before DH treated for cancer..
11/13 Very last attempt. New clinic. DE. Add intralipids and viagra. 9 eggs, 5 mature, 3 fertilized, 1 made it to day 3. no surprise, BFN..
04/14 Second "very last attempt" with 4th DE IVF.
04/05/14 13 eggs eggs retrieved, 7 mature, 7 make it to blast, 2 transferred, 2 frosties, BFP!! First Beta 4/21/14 = 92; Second Beta 4/23/14 = 265; 3rd Beta 4/25 613. May 9 ultrasound, right on track 6 weeks 5 days and hb 113 bpm. .
05/13/14 bleeding. May 14 no heartbeat. May 16 D & C. Are we allowed to say F words on here?