Jump to content



Photo
- - - - -

Egg damage from ICSI


  • Please log in to reply
6 replies to this topic

#1 BbDreams

BbDreams
  • Global 100+
  • 141 posts
  • Gender:Female
  • Location:Edmonton
  • Dx:N/A

Posted 11 March 2017 - 03:22 PM

I had 15 mature eggs, ICSI was preformed on all of them and 6 out of the 15 were damaged during the ICSI procedure.  To me that seems like quite a high number to have been damaged considering ICSI is recommend to couples with a low number of mature eggs retrieved to help ensure fertilization.  Is it normal for that many to be damaged from ICSI?



#2 amp77

amp77
  • 1000+
  • 2,676 posts
  • Gender:Female
  • Dx:Unexplained
  • My Clinic:OFC

Posted 11 March 2017 - 09:57 PM

Sounds high but we didn't do ICSI so I didn't look into it in detail.  I just wanted to say that I am sorry that it turned out that way.  I hope someone else has answers for you and I hope that you end up with some fantastic embryos!


  • BbDreams likes this

Age 39, DH 43 in Oct.

TTC on and off since 2007 before our second IVF, in 2014, brought us our beautiful son.

 

FET #1 -  Sept 2016

Day 1 - Sept. 9

Monitoring - Sept. 18-22

Lining Check - Sept. 22 (11.3 mm)

Transferred 5B-BB Sept. 25 - BFP!!!  HCG 890 @ 12dp5dt and Progesterone 95.
Midwife appointment Sept. 19 and first ultrasound Nov. 4
3 Frosties left

 

<a href="https://lilypie.com/"><img src="https://lbdf.lilypie.com/9GKrm4.png" width="400" height="80" border="0" alt="Lilypie Pregnancy tickers" /></a>

 

-------------------------------------------------------------------------------------------------------------------------------------

 

Seems like forever ago...

 

Age 37, DH 40.

TTC on and off since 2007

Unexplained Infertility

 

IVF #1 - April 2014 - BFN - no frosties

 

IVF #2 - July 2014 - BFP - 5B-AB and 4 frosties (5B-BB, 2x4B-BB and 3B-BB)

Apr. 13, 2015 - Daniel Erik was born at 5:05 am, weight 8 lbs, 13 oz, and 22" long.  He is perfect in every way.

 

 


#3 BbDreams

BbDreams
  • Global 100+
  • 141 posts
  • Gender:Female
  • Location:Edmonton
  • Dx:N/A

Posted 11 March 2017 - 10:25 PM

Thank you amp77, and congrats on your past IVF success :)



#4 returnable

returnable
  • 1000+
  • 1,814 posts
  • Gender:Female
  • Location:Whitby, ON
  • Interests:running, cooking, gardening, travelling
  • Dx:DOR
  • My Clinic:Trio, cycle monitoring at Lakeridge

Posted 12 March 2017 - 08:03 AM

Did the clinic tell you that the eggs were specifically damaged by ICSI?

Two IVFs and no chromosomally normal blasts to transfer...we are done with my eggs.


#5 SunshineTTC

SunshineTTC
  • Global 100+
  • 870 posts
  • Gender:Female
  • Location:Regina, SK
  • Dx:DOR
  • My Clinic:Aurora --> VFC

Posted 12 March 2017 - 01:49 PM

What clinic are you at?  Although there is a very small chance of ICSI causing damage, this does not normally happen (at all) with competent embryologists.  However ICSI does not guarantee fertilization, and it is definitely possible that 6 out of 15 might not have fertilized with ICSI.


  • CdnHockeyGal and Murried like this

Me: 40 41 42 43, single, FSH 6, LH 2 (FSH not high, but exceeds 2:1 ratio), DOR (AFC 5-7, v.low AMH), all else normal/healthy.

 


#6 BbDreams

BbDreams
  • Global 100+
  • 141 posts
  • Gender:Female
  • Location:Edmonton
  • Dx:N/A

Posted 12 March 2017 - 02:28 PM

Hi returnable and SunshineTTC, when the lab called and told me 6 out of the 15 didn't make it I asked the reason why and the woman explained several reasons to me why eggs don't 'make it' after ICSI, one of the reasons being that they were damaged from ICSI and I was told that was the case with my 6 that didn't make it.  It does seem like such a high number to have been damaged by the procedure considering specialists specifically will recommend ICSI to couples who only have a small number of eggs after retrieval to help ensure they get fertilized, but if the damage rate is that high it wouldn't make sense for them to do that.  I'm glad I have 9 embryos but I can't help but be upset that 40% of my eggs were damaged right off the bat since there's no telling how many out of the ones left are going to develop properly and come back normal after CCS.



#7 mouse

mouse

    Honorary PhD

  • Super Moderator
  • 6,732 posts
  • Gender:Female
  • Dx:Tubal
  • My Clinic:BKK/KWI/JHFC

Posted 12 March 2017 - 05:05 PM

I have had ICSI done and had none damaged - but I'm old and my eggs may be have been harder/tougher for sperm to penetrate. Is it possible that your eggs, or this batch in particular, are somehow more permeable/fragile and therefore more prone to this sort of damage?
  • CdnHockeyGal likes this
The plural of anecdote is not data.

Charity gives a meal; justice provides a place at the table.