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endometrin receptive assay (ERA).. Thin lining..pregnancy success


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#1 emaKG

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Posted 04 January 2017 - 10:58 PM

Hi there. Just had an ERA done after 6 failed embryo transfers of pgs tested embryos. Found out I need one extra day on progesterone. I have a chronically thin lining. My lining was a 6.2 for the ERA test and it came back as pre receptive still. I also had my endometrin tested two days later which showed post receptive so we know I need the one extra day. Now my lining is stuck around a 6 again so we are trying to get it thicker to start progesterone. Any success stories with thin linings ans pregnancy or anyone pregnant after the ERA test??

Ive tried almost everything for my thin lining. My estrogen levels get to over 1k and my lining gets triple striped but does get thick. I've also implanted before but always miscarry before heart beat is detected.

#2 amazing grace

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Posted 05 January 2017 - 07:14 PM

I just completed my fourth FET and negative again. This last one was after I did the ERA TEST AND BASICALLY SPENT 1100 DOLLARS FOR NOTHING! Like you, mine came back pre-receptive did two extra days of progesterone and still negative. To be honest I am really annoyed at the fact that I did this test, I almost feel it is a waste of money. I got pregnant on the usual progesterone protocol once before and would have carried to term but lost my baby to a birth defect, got pregnant the second time and miscarried at almost 7 weeks and since then, I have not been able to get pregnant. I just don't get it so thought this ERA test was the answer. I did though question that since I got pregnant twice on the usual progesterone protocol, why would that change? However, I was talked into doing it....anything for answers right? I am sorry I don't have positive thoughts about this test. Regarding your lining, I am not sure if your RE has given you medication for it but there are things that they can provide. I tried viagra and tomaxofin which neither did anything for me. What worked for me was Climara patches combined with vaginal estrace. If you look at the postings for thin lining, there is some very helpful advice there. Wishing you all the best.



#3 emaKG

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Posted 05 January 2017 - 10:39 PM

Hey there. I am so glad you posted. That sucks so bad that you did the ERA test and still got a negative. How was your ERA only 1,100? I spent 1500$ by doing it twice. Did you transfer one or two embryos and were they pgs tested? What did your Dr day on whey they think this didn't work??? Will you transfer again on the day the ERA test showed receptive??? What was your lining at? Do they have any idea why you have gotten pregnant before on a different number of days of progesterone? I would ask ivigen thst question.

I've tried all sorts of meds for my lining. Vaginal estradiol does nothing for me. I do del estrogen injections and patches now.

#4 cdgal1981

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Posted 06 January 2017 - 07:01 PM

I am a success story after ERA biopsy.

I had 3 previous transfers, 4 blastocysts and all I had was one chemical pregnancy.

The tests showed I needed one more day of progesterone.

I am currently 11 weeks pregnant with twins, my last two blastocysts.

Best of luck to you :-)

Me 33, DH 38

TTC for 3.5 years

DX WAS - unexplained infertility after DSA = male factor (95% sperm antibodies)

 

Received referral to Conceptia on April 16/14

 

1st appointment at Conceptia was May 28/14, recommended IVF/icsi

 

IVF consult July 24/14

 

IVF #1

Started BCP September 7th, Suprefact September 24th and Puregon/Pregnyl October 6th

Oct 17 ER - 11 eggs 10 mature 8 fertilized

Oct 22 ET - 1 4BB & 1 3BB blast

1 Frostie

Nov 3 - Beta confirmed BFN

 

FET#1

Jan 9/15 - Baseline good to go ET tentatively scheduled for Jan 29

Cancelled - estradiol not cooperating

 

IVF#2

Started BCP February 4, Superfact March 3 and Puregon/Pregnyl March 15th

March 26 ER - 9 eggs 6 fertilized

March 31 ET - 1 3AA blast

2 Frosties

April 13 - Beta confirmed BFN

 

FET #2 - August 2015 - Chemical pregnancy

Last FET Fall 2016

 


#5 emaKG

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Posted 06 January 2017 - 08:55 PM

Wow congrats!!!! Just the news I needed to hear today! Praying for you that all continues to go well ans hoping I can be in your shoes next week! What protocol did you do for your mock and what did you do for the transfer?? Do you have thinner linings?

#6 cdgal1981

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Posted 07 January 2017 - 11:13 AM

I never really had lining issues but they were never super thick either, always right around 8-8.5.

I'm not sure what made the difference but my lining for this transfer was 10.9. We did not do any supression(birth control and suprefact) I just started my cycle and started taking estrogen on day 3. Another thing that happened was instead of brand name estrace my pharmacy subistuted it for generic estrogen. I had never had any adverse side effects from the brand name but when taking the generic I was really sick for a few days, and low and behold my lining was thicker.

Me 33, DH 38

TTC for 3.5 years

DX WAS - unexplained infertility after DSA = male factor (95% sperm antibodies)

 

Received referral to Conceptia on April 16/14

 

1st appointment at Conceptia was May 28/14, recommended IVF/icsi

 

IVF consult July 24/14

 

IVF #1

Started BCP September 7th, Suprefact September 24th and Puregon/Pregnyl October 6th

Oct 17 ER - 11 eggs 10 mature 8 fertilized

Oct 22 ET - 1 4BB & 1 3BB blast

1 Frostie

Nov 3 - Beta confirmed BFN

 

FET#1

Jan 9/15 - Baseline good to go ET tentatively scheduled for Jan 29

Cancelled - estradiol not cooperating

 

IVF#2

Started BCP February 4, Superfact March 3 and Puregon/Pregnyl March 15th

March 26 ER - 9 eggs 6 fertilized

March 31 ET - 1 3AA blast

2 Frosties

April 13 - Beta confirmed BFN

 

FET #2 - August 2015 - Chemical pregnancy

Last FET Fall 2016

 


#7 emaKG

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Posted 10 January 2017 - 07:17 PM

@Cdgal maybe you can help ease my mind here. My transfer is at 12:45pm and I'm worried we are doing it too late in the day. After 5 nights of taking pio at 530pm I was prereceptive. So needed 24 more hours on pio. This was done around 9am. Then after 7 nights on pio taken at 530pm I was post receptive and this was done at 9 am. My worry is since my transfer isn't at 9am after 6 nights of pio taken at 530pm I'll miss the window and be transferring too late in the day and only 16 hours earlier than my post receptive test and that test didn't say 12 hours less......

#8 HFLO

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Posted 11 January 2017 - 03:10 AM

Emakg: best of luck with your transfer, try not to stress if that's possible! I think you're close enough with your biopsies being done at 9 and transfer scheduled at 12:45. That's less than 4 hours difference. From everything I've read, the implantation window is 24 hours (12 hours at minimum) and you're well within that! Update us when you can!

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#9 emaKG

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Posted 11 January 2017 - 06:54 AM

Thanks HFLO! Had a moment of panic last night but some sleep did me well. You know how it goes lol one minute you're fine next everything you're questioning. Transfer is today! I'm staying stress free!xo

#10 HFLO

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Posted 12 January 2017 - 02:41 AM

Congrats on being PUPO!! Will you POAS during the 2ww or wait for beta?

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#11 emaKG

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Posted 12 January 2017 - 08:53 AM

Thanks so much!!!! I told myself I will not test this time. Hcg test is on 13dpt.

I can't remember.... How are things going for you???

#12 HFLO

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Posted 12 January 2017 - 01:37 PM

I just had my suppression check this morning at my local clinic. They will send the bloodwork results and ultrasound report to my RE today. Hopefully I can get the green light to start the FET protocol!
It's so hard not to test. I've done the 2ww both ways and still don't know what I'll do next time. I'm excited for you!

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#13 emaKG

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Posted 12 January 2017 - 02:32 PM

Yay can't wait to hear!

#14 HFLO

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Posted 13 January 2017 - 02:20 AM

I got the go ahead to remove the nuvaring tonight. I'll be starting delestrogen injections on the 16th! Praying it's finally our time!

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#15 emaKG

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Posted 13 January 2017 - 07:19 AM

That's so great! I'm feeling very hopeful for you!!

#16 maryhope

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Posted 23 January 2017 - 10:40 PM

hi Ladies, can you tell me how the ERA test is done? I mean the required medication, schedule and period. next week I have an appointment with my doc to make a decision if I want to do this test or go for FET with biopsy. I had three fet and one fresh transfer.

#17 breezyboo

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Posted 23 January 2017 - 11:00 PM

You have to mimick exactly the meds you would take for a FET...Then instead of transfer they biopsy
Me: 30Hypothyroid,Endo, MTHFR, elevated Cytokines,TNF 36.8 (13.2-30.6) IFN 27.5(5.8-20.5). 2006-Twin m/c @ 8wks w/ex BF followed by 22 BFN's ... 6 months on clomid & 4 IUI's.Married for 5yrs to the love of my life. We want to make that love childDH: 31 Azoospermia (NOA) FSH 28.3, LH & testosterone levels normal Normal genetics. NOA possibly due to injury when younger.IVF/ICSI Barbados 201312/3-ER! 18 eggs, 12 mature & 10 fertilized!12/8-ET! 2 beautiful beans snuggled into place! 7 snowflakes!12/13- BFP12/17- Beta 9dp5dt 255!12/19 Beta 11dp5dt 392, 13dp5dt 585???12/26 Beta 3,388!1/2 U/S TWINS!! HB's 122& 1211/20 U/S Lost Baby B @ 7-8 weeks. Baby A doing great!IT'S A BOY!!!4/29 @ 6 months our sweet boy became an angel ABSOLUTELY HEARTBROKENFET January 2015 CANCELLED thin lining WTF?FET September 2015 CANCELLED due to a cyst/delayed period...You gotta be kidding me?!FET October 2015 BFNICSI/PGS Banking @ MCRM Feb & May 2016Feb & May 2016= 3 girls & 4 boys
FET October 13 2016 1 PGS normal girl = BFP!!!!! :D

#18 maryhope

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Posted 24 January 2017 - 12:32 AM

thanks for your answer. wondering if it starts since suprefact or strace medication (takes one cycle or two cycles)

#19 maryhope

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Posted 24 January 2017 - 09:59 PM

today my doctor said ERA test won't change my result as I had no problem with lining. he wants me to go for last FET with biopsy not the test. does anybody have an experience of doing this test with good lining.

#20 HFLO

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Posted 25 January 2017 - 10:50 AM

emakg: thinking of you today and curious about your outcome? I think your beta was scheduled for yesterday or today? Praying you got a bfp!
Mary hope: I didn't have the testing done due to lining issues, it was just one more piece of information to try to get a positive outcome. The ERA is useful if you've had multiple failed transfers, particularly with euploid embryos. You go through a mock cycle, with all the meds you would take for a real FeT and then instead of the transfer you have a biopsy done. The test tells you if you are receptive, prereceptive or postreceptive on the day they biopsied (intended transfer day). Based on the results they can transfer earlier or later if you have a displaced implantation window. And then you would proceed with the real FET making sure to follow the exact med protocol. Best of luck to you on your upcoming cycle!

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#21 maryhope

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Posted 25 January 2017 - 07:49 PM

thanks HFLO. I had an appointment with my doctor today and he did not accept to do ERA. so I will go for FET with biopsy.

#22 emaKG

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Posted 25 January 2017 - 08:43 PM

Hi HFLO - I will have a repeat beta tomorrow at 15dp5dt but the 13dp5dt it was 2,072. Cautiously optimistic. Been able to.make it to five weeks before. How are you?

#23 HFLO

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Posted 26 January 2017 - 07:37 PM

Mary hope: I can't see your signature, so I'm not sure of your history, but I'm sure your doctor has good reasons to think that ERA isn't needed. Good luck with the FET.
EmaKG: I'm so ecstatic for you!! Congratulations!! How many embryos did you transfer?
AFM: time is moving slowly! Estradiol is rising appropriately with delestrogen injections. Next check is Feb 1st to see if my lining is cooperating and if I can start PIO. Praying I can proceed with transfer on Feb 7th

DH: 39 - MF, low motility, low count

Me: 40 - lining issues, hx of polyps and fibroids

 

TTC since 2008.

Started IVF journey in 2012, 3 fresh cycles and 3 FET attempts with first RE resulted in 3 BFNs and 3 cancelled transfers. No BFPs, no chemicals, never even seen a double line on HPT. cry.gif

Changed REs in 2015.  Repeated all tests and decided to bank embryos for PGS testing due to history of BFNs.  After 3 cycles and PGS testing - finally achieved 2 PGS normal embryos. banana.gifbanana.gif RE suggested ERA testing to determine implantation window. Mock cycle in May 2016 and July 2016, receptive results showing that 7 days of progesterone support required.

FET attempt #1 with new RE - Sept 2016: cancelled due to pharmacy med mixup th_agrr.gif

FET attempt #2 with new RE - Nov 2016: cancelled again - lining not trilaminar eusa_wall.gif

FET #3 with new RE - Feb 2017 eusa_pray.gif - suppression check and removed nuvaring on Jan 12th.  To start delestrogen injections Jan 16th. Final lining check on Feb 1st - got the green light to transfer finally!!yahoo.gif Feb 7th transferred one 5bb euploid embryo, beta scheduled for Feb 21st. eusa_pray.gif Symptoms: strong sense of smell, very tired, tugging/pulling/small cramps, sore breasts, and heartburn. Caved and POAS at 4.5dpt and saw 2 lines for the very first time in my life, POAS every day until second line was darker than control! th_acheerlead.gif. Asked clinic to move up beta.  First beta 9dp5dt=110; Second beta 11dp5dt=269; Third beta 13dp5dt=685. Ultrasound scheduled for March 3rd eusa_pray.gifeusa_pray.gifeusa_pray.gif

 


#24 emaKG

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Posted 26 January 2017 - 09:20 PM

Just saw when your lining check is and transfer! I just private messaged you those questions! We transfered two pgs embryos

#25 maryhope

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Posted 05 February 2017 - 11:25 PM

Thanks HFLo, I have 3 FET and 1 fresh transfer, resulted one chemical and 3 BFN. Today I starated suprefact and biopsy scratch will be on Wednesday. hope it works.
Good luck with your FET too.