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#5151 lady32

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Posted 12 October 2016 - 10:12 AM

Hello all,

 

New to this forum.  My husband and I just found out last week that he has azoospermia.  2 SAs confirmed it.  We'd been TTC for about a year when we decided we should both get checked.  We're in complete shock and the last week has been an absolute rollercoaster of emotions.  All we know so far is that his hormone levels are within normal range for testosterone, FSH, and LH.  We're waiting for appointment with the urologist to talk about next steps..

 

From what I've read, obstructive seems to be the best case scenario.  Since his bloodwork is normal, we think this is still a possibility but we know it's not guaranteed.  Based on my research, a biopsy will be the next step to confirm either way.  We are both 32 years old and desperate to have a baby of our own.

 

Our hearts are completely broken!!!

 

My gut tells me the sperm are in there but they are just trapped.  I really hope this is the case!!!  He had 2 inguinal hernia surgeries down there as a child and I really believe they messed something up.

 

We're keeping this entire thing between the 2 of us for the time being.  We are in it together and we're a great team, but it's really quite hard.  Especially knowing that we have a very long and costly road ahead with no idea what the end result is going to be.

 

Threads like these ones give me comfort knowing we are not alone in this.

 

Shout out to all you ladies and gents in similar situations xoxoxo



#5152 Kath

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Posted 12 October 2016 - 11:45 AM

Hi lady32,

 Welcome to the group! I'm so sorry you have had to come here, but I think you'll find it very informative and supportive. I too remember the initial gut wrenching shock after finding out about my DH's azoospermia and am feeling for you right now. I remember us just walking around in a daze for a week or so after and feeling so sad. And wanting things to happen straight away to find out what was wrong of course! It was the not knowing that really got to me. Once we had a proper diagnosis things got much easier to handle and accept.

 

Do you have an appointment with a fertility centre? The first step would be to get an initial appointment. We found that tests happened / a diagnosis was made much more quickly through our local fertility centre than through waiting for a urologist appointment. In fact we cancelled the urology appointment as we'd already started the IVF process by the time the appointment came around and didn't need it anymore. If your clinic has a long wait list see if you can be put on a cancellation list for an initial appointment.

 

If your DH's hormone levels were normal, the next step would likely be more blood tests to test for any genetic conditions such as kleinfelters, cystic fibrosis, or other sex chromosome abnormalities (sex chromosome abnormaltities are unlikely if hormone levels are normal though). They can take around 6 weeks to come back. Hopefully they'd do these tests before a biopsy, as it can take a while to recover from a biopsy. If these are all normal then a biopsy, or PESA, TESA, or MESA would likely be next.

 

Previous hernia operations are a very common cause of obstructive azoospermia. And you are right in thinking that obstructive azoo is the best case scenario, as it is easier to treat, so hopefully this is the case for you too. My DH had obstructive azoo, which we found out was due to him having 'atypical cystic fibrosis' which means he has 2 different CF mutations, which cause the vas deferens to be missing. So his hormone levels were also completely normal and we had no idea that that would be the problem. No one in his family has ever had CF and we wouldn't have known without the fertility genetic tests, and he didn't have any other symptoms such as lung problems. So this could also be a possibility for your husband.

 

Once we had the diagnosis of obstructive azoo due to CF, things got moving fairly quickly. I had to have genetic tests to check I wasn't a carrier of any CF mutations first. Then he had a successful PESA (a very simple operation for obstructive azoo where they basically get sperm directly from the testes using a syringe! It's not as bad as it sounds and is done under local anaesthetic), the sperm that was found was frozen, and then I started IVF meds about 4 weeks later. We were lucky in that it worked first time, and I am now almost 16 weeks pregnant, and have 2 5-day embryos frozen for the future.

 

I'd say the most important thing for you to do right now is get into a fertility clinic (even before urologist). And don't give up hope! My DH is 40, and I am now 34. We thought we were on the 'old' side to be having so many problems, but we were both in great shape for ivf apparently! There are lots of hurdles to jump through and it's not easy, but this diagnosis doesn't mean you can't have kids.

 

To give you a rough timeline for us: tried for just over 1 year (2014-2015) unsuccessfully to get pregnant; 1st Jan 2016 went to walk-in GP clinic to get referral to fertility clinic; While waiting for appointment the GP did all hormone and sperm tests, hence finding out about azoospermia; Got cancellation appointment for fertility clinic for mid February 2016 (normally it's a 6 month wait); genetic tests were sent away by fertility clinic and results came back in April; My genetic tests came back mid May; DH had PESA performed late May; I started ivf early July; got positive pregnancy test early August; graduated from fertility clinic mid September, and now I will be seen by a GP for the rest of the pregnancy.

 

Others on this thread have had much longer more difficult journeys unfortunately. But still don't give up hope!

 

Feel free to ask any questions and keep us informed. 

Take care and good luck :-) XXX


TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5153 lady32

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Posted 12 October 2016 - 01:38 PM

Hey Kath,

 

Thank you so much for the supportive and informative post.  It's nice to hear from someone who understands what it's like to be in this difficult situation.

 

We've also been referred to the local fertility clinic (private one).  Our doctor is sending that over today.   The same urologist also works at this private clinic - he does both public and private care.

 

My husband chatted with the urologist's public clinic today and was told they are booking appointments for December currently - 2 months out, not so bad.  Also said we can go on the cancellation list which could get us in quicker.

 

So we are coming at this from both channels, hoping for the best.  I am just saying a prayer each day that there are sperm in there for us to use.  It's driving us crazy not knowing.  We need a way to calm down and chill during the wait times - it's so hard!!!

 

We've already decided we're going to try whatever it takes to make this happen - we will not give up.

 

Hugs to everyone dealing with infertility.  You really don't understand what it's like until it happens to you, and you really don't see it coming either!  All this time I thought there was something wrong with me - fingers crossed this is our only issue.  I've had day 3 and 21 blood tests, both of which are good. 



#5154 lady32

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Posted 12 October 2016 - 01:44 PM

Kath, I also meant to say that I'm so happy to see your story ended on a positive note.  I am praying the same outcome for us!!!  Also wishing everything goes well for the rest of your pregnancy - how lucky are we to be living in an age of modern medicine with the technology to help us???


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#5155 Kath

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Posted 14 October 2016 - 02:43 PM

Thank you! Yes, unlucky to be dealing with it, but so incredibly lucky to get some help!


TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5156 Dani88

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Posted 16 October 2016 - 11:35 AM

Dani88 and Hopefulmum - Sad to hear your news and hope you've both got the support of your partner and family, friends.

We are in a different situation. Our RE brought up the option of donor sperm in our last appointment to see if quality was really the issue. My partner and I couldn't really discuss it afterwards. So overwhelming. We feel lucky to have options but are not financially able to pursue rounds of treatment and need to factor in my age.

Thoughts are with you both. So difficult to have your hope for success with the micro TESE dashed.

Dani88 - I hope the donor IUI is a success. Are you doing that with TRIO?

 

Thanks.  No, I am doing IUI with the Orillia Fertility Clinic.  I'm from Barrie and heard good things about Orillia over Barrie... so it's about a half hour drive where TRIO would be well over an hour.  I had my 1st IUI on October 4th and find out tomorrow if it was successful.


Me:  27,  DH:  27 (Non-Obstructive Azoospermia) - TTC since October 2014
Micro-TESE August 23, 2016
Unmedicated Donor IUI - October 4, 2016 - BFN
d5YBm5.pngJH5wm5.pngB5jIm5.png

#5157 Kath

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Posted 17 October 2016 - 04:21 PM

 

Dani88 and Hopefulmum - Sad to hear your news and hope you've both got the support of your partner and family, friends.

We are in a different situation. Our RE brought up the option of donor sperm in our last appointment to see if quality was really the issue. My partner and I couldn't really discuss it afterwards. So overwhelming. We feel lucky to have options but are not financially able to pursue rounds of treatment and need to factor in my age.

Thoughts are with you both. So difficult to have your hope for success with the micro TESE dashed.

Dani88 - I hope the donor IUI is a success. Are you doing that with TRIO?

 

Thanks.  No, I am doing IUI with the Orillia Fertility Clinic.  I'm from Barrie and heard good things about Orillia over Barrie... so it's about a half hour drive where TRIO would be well over an hour.  I had my 1st IUI on October 4th and find out tomorrow if it was success

 

 

Hope it all went well Dani. Fingers are firmly crossed for you.


TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5158 HopefulMum

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Posted 31 October 2016 - 06:58 AM

Hi Ladies, thanks so much for your kind words. They really helped me in that moment when I was at my wit's. I have been having issues logging in and Just found time to do the whole 'activate and re-set password's thing. Just wanted to give an update that the days are brighter now and DH and I are doing a lot better. We are not sure what would be next but will make a decision in time.

Dani, I am sorry about your news but glad to hear that you are trying with a donor. I wish you and hubby all the best and pray for a favourable outcome.

Lady32, I am sorry you have found yourself here but being on this forum is a wealth of help and encouragement. It's not like we can discuss these things with just anyone. ***Fingers crossed** that your feeling of DH having ob azoo is correct (that's still tough but provides more hope) One advice I would give is to follow up with the doctors office as much as you can, they see so many people so I found it was up to me to take charge. It helps to ask what blood work needs to be done ahead of the appointment so you can use the appointment to discuss the results (nothing sucks like waiting 3 months for an appt only to be given forms for tests and asked to come back in another three months) Also you can call to ask about the results instead of waiting for the next appointment, it gets the doc to look at your chart and make any changes to medications before your appointment.

#5159 HopefulMum

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Posted 31 October 2016 - 07:02 AM

Also we ended up freezing the sample, I don't regret the decision even though it cost money (we are not rolling in dough) but it seemed like the best thing at the time.

#5160 lady32

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Posted 01 November 2016 - 09:30 AM

Hopeful Mom, thank you so much for the kind words.

 

We found out today that we won't have the appointment with the urologist until January.  His name is Grantmyre in Halifax.  They had previously told us it would be December but I guess December has filled up and she'll need to wait for his January schedule before she can book us in.  We are first in line on the cancellation list and I hope so bad we can get in sooner than that.  

 

 

I found this thing online, and it says if semen volume is normal and hormone levels are also normal, the next step would be biopsy:   https://www.ncbi.nlm...les/PMC2874589/

 

Looks to me, based on this article, they will only do the genetic testing if semen volume is low?  I'm hoping this is the case because it seems like those tests can take forever from what I've read.

 

Also, I wonder how long that initial meeting would a biopsy be scheduled.  Probably a few months later :(

 

I wonder - do they collect sperm at the same time as biopsy if they're able to find it?  Or do they only do the biopsy to determine if its obstructive or not, and then collect sperm on a different day?

 

The waiting is so hard.

 

I went to brunch with 3 of my girlfriends on the weekend.  One is pregnant and the other 2 have babies.  This is all they talked about the entire time and I just felt so awful - they don't know what we're going through :(

 

I got in the car afterward and just cried.  I wouldn't wish this on anyone!

 

 

 

 

 

 



#5161 AlinaT

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Posted 01 November 2016 - 05:04 PM

Hi everyone, 

There are a lot of forums posts online to read through and I think I might have touched everyone in the last few months. This forum seemed like the best to join and hopefully get some support and advice as our process continues. Here is our story - I am very curious if anyone had a similar story with successful outcomes. 

My bloodwork is normal and AMH is ideal for someone my age (36)

Husband had 2 SAs in late July - both 0 after centrifugation

Met with a male infertility expert who ordered bloodwork in late August

Husband's bloodwork shows slightly low T and slightly elevated FSH - all other hormones normal

No Karyotyope or Genetic problems

No structural problems

Testicles on the small side 

Diagnosed him officially with non-obstructive azoospermia in late Sept

Husband has been on Clomid + Vit E, CoQ10, Zinc, Selenium, L-Arginine Ornothine, Korean Ginseng, N-Acetyl-L-Cysteine, Ashwagandha Extract,  Tongkat Ali, and Vit C since late Sept

 

We have another SA schedule for January to see if the mixture above helps. The doctor has said there is little to no chance, but since my fertility is so strong, said that it was fine to wait a few months if we wanted to. I have heard a mixed bag of  anecdotes whether Clomid is best alone or mixed, and can find no research in peer reviewed journals. (I prefer research based information as I have a PhD and understand how research works.) If he still has 0 sperm (or severely reduced sperm) he will undergo a MicroTESE.

 

If anyone has a similar story (male hormone #'s and exams are the same) and has had success either in changing an SA from 0 to "anything" or having a successful MicroTESE - I would love to hear about it. 

 

Thanks for posting such supportive and helpful comments - you gave me the strength to start my own account and seek a support group. 



#5162 Kath

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Posted 01 November 2016 - 05:37 PM

Hi Ladies, thanks so much for your kind words. They really helped me in that moment when I was at my wit's. I have been having issues logging in and Just found time to do the whole 'activate and re-set password's thing. Just wanted to give an update that the days are brighter now and DH and I are doing a lot better. We are not sure what would be next but will make a decision in time.
 

 

So glad to hear you are feeling more positive Hopeful. Must have been so difficult to come to terms with. I hope to hear more positive news from you in the near future. ((Hugs))

 

 

 

I found this thing online, and it says if semen volume is normal and hormone levels are also normal, the next step would be biopsy:   https://www.ncbi.nlm...les/PMC2874589/

 

Looks to me, based on this article, they will only do the genetic testing if semen volume is low?  I'm hoping this is the case because it seems like those tests can take forever from what I've read.

 

Also, I wonder how long that initial meeting would a biopsy be scheduled.  Probably a few months later sad.png

 

I wonder - do they collect sperm at the same time as biopsy if they're able to find it?  Or do they only do the biopsy to determine if its obstructive or not, and then collect sperm on a different day?

 

 

I think it might depend on the specialist that you see Lady32 as to whether they will do the genetic testing before a biopsy. Although I thought they nearly always did it before a biopsy to rule out certain things first. In our case they did, and we were pleased as we were able to rule out many conditions that are linked to non-obstructive azoo, and then didn't need the biopsy (we were then able to go straight ahead with the PESA, which is much less complicated). My DH had normal semen volume levels (within the normal range, although at the low end) and they thought he had a vas deferens (turns out he doesn't) and couldn't find any signs of non-obstructive azoo yet they sent off for the genetic / karyotype testing anyway first. This perhaps might be something that you could get done before your Jan appointment if you ask your GP? Or you could ask for the blood forms from your fertility clinic / urologist now to try and get some answers before then? Might be worth a try to chase the clinic and find out if it's possible! It's just a blood test and took about 4-6 weeks for all of those results to come back. My DH also had to have a testicular ultrasound before they would do anything else - but this can be done privately if you want to speed things up. I found that being that irritating patient that keeps phoning around and trying to speed things up really did work quite well!

 

The trouble with biopsies is that they can take 6 months to recover from, so if they don't find sperm then it's another long wait until they can 'go in' again. But they do usually freeze anything they find - they will ask you before the op.

 

Totally feel your frustration with the waiting game - it's sometimes the hardest part I think. Really hope the next few months speed by for you. Big hugs :)

 

Hi everyone, 

There are a lot of forums posts online to read through and I think I might have touched everyone in the last few months. This forum seemed like the best to join and hopefully get some support and advice as our process continues. Here is our story - I am very curious if anyone had a similar story with successful outcomes. 

My bloodwork is normal and AMH is ideal for someone my age (36)

Husband had 2 SAs in late July - both 0 after centrifugation

Met with a male infertility expert who ordered bloodwork in late August

Husband's bloodwork shows slightly low T and slightly elevated FSH - all other hormones normal

No Karyotyope or Genetic problems

No structural problems

Testicles on the small side 

Diagnosed him officially with non-obstructive azoospermia in late Sept

Husband has been on Clomid + Vit E, CoQ10, Zinc, Selenium, L-Arginine Ornothine, Korean Ginseng, N-Acetyl-L-Cysteine, Ashwagandha Extract,  Tongkat Ali, and Vit C since late Sept

 

We have another SA schedule for January to see if the mixture above helps. The doctor has said there is little to no chance, but since my fertility is so strong, said that it was fine to wait a few months if we wanted to. I have heard a mixed bag of  anecdotes whether Clomid is best alone or mixed, and can find no research in peer reviewed journals. (I prefer research based information as I have a PhD and understand how research works.) 

 

If anyone has a similar story (male hormone #'s and exams are the same) and has had success either in changing an SA from 0 to "anything" or having a successful MicroTESE - I would love to hear about it. 

 

Thanks for posting such supportive and helpful comments - you gave me the strength to start my own account and seek a support group. 

 

Hi AlinaT, welcome to the group, and so sorry you are here. My story isn't too similar, but I know others on this thread have had varying degrees of luck with different protocols for non-obstructive azoo and I'm sure they will weigh. Wishing you all the strength and luck in the world!


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TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5163 lady32

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Posted 06 November 2016 - 02:35 PM

Hey Ladies,

 

So I've been thinking all this time that my husband's hormone levels were within normal range, suggesting it's still possible that his azoospermia is due to an obstruction.  According to the lab 12.0 was the upper limit of normal for FSH.  His came back 11.8, just below.

 

Now I am reading all of these Q&As on this website of Dr Turek in the US:  http://www.theturekc...th-azoospermia/

 

Dr Turek says if FSH is above 8, then it's a case of non-obstructive.  I am now in panic mode!!

 

What did your doctors say was considered high?



#5164 lady32

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Posted 28 November 2016 - 03:31 PM

Hi ladies,

 

Still wondering, based on what you know, do doctors consider 11.8 high for FSH?

 

It's borderline within the normal range, according to the lab, with the upper limit of their reference range at 12.0.

 

I've read on other websites that anything over 8 means testicular failure, and rules out obstruction as the cause.  Some websites say anything as high as 15 can be considered normal.

 

Luckily we have an earlier appointment with the urologist now - next Thursday.

 

Wondering what we can expect.

 

Thanks!!

 



#5165 Kath

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Posted 02 December 2016 - 11:51 AM

Hey lady32,

It's really hard to know if it's high or not as all labs have different values. I looked at our lab's values and they have a normal range up to 10.5. If your hubby is within the normal range for your lab though then it still is normal! Although I agree it's on the high end. Have you been able to follow up with the urologist? Any more news? I'm keeping my fingers crossed for you both. Big hugs :)

TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5166 lady32

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Posted 12 December 2016 - 02:00 PM

Back with an update.

 

We had our appointment with the urologist on Thursday last week.  He said even though the FSH is within the "normal" range according to lab, it's actually too high.  He said FSH should be below 5 (his was 11.8).

 

I have no clue why the lab would say 12 is normal when it clearly isn't!!!  So annoying.

 

On the other hand, he said my husband's prior pediatric surgeries (inguinal hernia repairs) does provide a fair argument that obstruction could still be at play.  His guess is 25% chance obstructive, 75% chance non-obstructive.

 

We'll proceed with the biopsy in January so that we know for sure.

 

I'll be honest, my window of hope is shrinking by the day :(

 

He said if it's obstructive, he can proceed with extraction sometime in March.

 

He said if it's non-obstructive it would be either:  hypospermatogenesis, maturation arrest, or sertoli cell only syndrome.

 

If it's hypo, he is ok doing the surgery to attempt extraction.  If it's the other 2 he said he wouldn't go there.  If you want to explore those you should go see this Dr Schlegel in New York who is apparently the best in the world and costs $30-40k.

 

Back to the waiting game for us :(



#5167 lady32

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Posted 03 January 2017 - 08:45 AM

Biopsy is scheduled for 2 weeks from today, we just found out.  Please, everyone, say a prayer for us.

 

I'm scared to find out the outcome, but really just want to know once and for all.



#5168 HopefulMum

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Posted 04 January 2017 - 07:07 PM

I wish you and your DH all the best lady32. Sending positive vibes to you for a positive outcome.

#5169 HopefulMum

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Posted 04 January 2017 - 07:08 PM

I wish you and your DH all the best lady32. Sending positive vibes to you for a positive outcome.

#5170 lady32

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Posted 05 January 2017 - 02:50 PM

Thanks so much hopefulmum xo.  It's so hard not to obsess over this stuff.  I swear I think I've read every freakin article and study out there trying to determine what our odds of success are. 


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#5171 SusieBlue

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Posted 11 January 2017 - 10:23 PM

Hi Ladies,

 

My husband has been diagnosed with non-obstructive azoospermia (and so we also begin this insane journey). His micro-TESE surgery is scheduled for March, 2017. His testosterone / chromosome tests all came back normal but he has a very high FSH level and the way it was explained to us was that his pituitary gland is sending the right signals but his body is not listening and therefore not creating sperm - so frustrating as I am sure many of you ladies know. 

 

We are with Hannam and will be getting the surgery at Mt Sinai with Dr. Lo. We met with Hannam yesterday to go over questions etc and he advised that although it is not scientific he told my DH to abstain from mid-February on wards until his surgery in early March. This makes sense to me because surely we want as much sperm as possible when the surgery is happening for any chance to find something for IVF.

 

I am just curious if those of you who's husband has had the procedure - did any Drs tell him to abstain for a long time before surgery? I am looking over our documentation from Mt Sinai and I don't seem to see anything telling us the length of when to abstain. 

 

Thank you so much for any insight.

 

 

 



#5172 HopefulMum

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Posted 12 January 2017 - 08:32 PM

Hi SusieBlue,
I am sorry that you have to be here. When my DH had his mTESE, we were told that he didn't have to abstain before the surgery as it wouldn't make a difference. Our doctor seemed to be very scientific though. If Dr Lo suggested abstaining, it may be worth a try. Best of luck to you and your hubby.

#5173 GardenerWife

GardenerWife
  • Just Hatched
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  • Gender:Female
  • Location:ON
  • Dx:Male Factor
  • My Clinic:LHSC

Posted 26 January 2017 - 09:02 AM

Hi Ladies, I am joining in and would love to chat with others in a similar situation. It's been a long road. 

 

After trying on our own for a year we were referred to an RE. We had low counts (1 million or so) a year ago then we were referred to the fertility urologist, and from there to an endocrinologist. Since then count has decreased. DH was diagnosed with NOA and low hormones and after 3 months on climid his FSH is now back up into normal range (from 1 to 2.5) but there are still no sperm. All hormones are normal. Endocrinologist wants to repeat SA in 3 more months. We just met with the RE again to discuss a plan/ next steps and DH will have PESA sperm extraction performed to see if they can get any sperm that way for our IVF. Our appt for the consult for that is at the end of March, so that the climid has a bit more time to work. They brought up donor sperm and it's crushed us both. We'll do anything we can to have our own biological child. 

 

Has anyone had a successful PESA after a 0 count? I know that low hormones are traditionally easier to treat than high hormones, but we were very discouraged that there was nothing after 3 months of the hormones being in the right range. How much did you pay for the PESA on top of the IVF cycle? The cost isn't a barrier for us, I am just wondering how much to plan for it. 

 

Any advice/ wisdom/ insight on any of this is greatly appreciated, thank you.


Me- 34 / DH 36

TTC since early 2015

Feb 2016 - diagnosed with severe MFI 

Sept 2016 - dx azoospermia / low hormones so DH starts clomid 

Jan 2017 - still no sperm

Now just trying to figure out how to make this work.


#5174 Kath

Kath
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  • Dx:Male Factor
  • My Clinic:VFC

Posted 26 January 2017 - 12:13 PM

Hi GardenerWife,

 

So sorry you are here. We're not quite in the same situation as you, as DH's turned out to be obstructive. But I can give you an idea of the costs we paid: the PESA cost us $1200 (CAD) on top of the IVF with ICSI, and we ended up spending around $14,000 altogether. Probably a little more if I take into account vitamins, follow-up bloodwork, Harmony test etc. We went for a plan that would allow us to have cheaper IVF on round 2 if we needed it, and I'm glad we made that decision (even though we were incredibly lucky and got pregnant on the first round). 

 

Hope everyone is doing OK. Lady32, any news? Hopefulmum, how are you doing? SusieBlue how are things going? AlinaT did your partner have the next SA?

 

Kath X


TTC since Jan 2015

Me (34) = all looks ok so far

DH (40) = diagnosed with azoospermia Jan 2016

 

March 2016: Finally have some answers:

DH has 2 different cystic fibrosis mutations, making him a compound heterozygous carrier for CF
(meaning he doesn't have full-blown CF but a milder form with Obstructive Azoospermia)

Genetic testing shows I am not a carrier - no PGD of embryos needed, although our baby will be a CF carrier.

 

May 2016: DH had successful PESA

 

IVF#1: June/July 2016

15 eggs retrieved, 14 mature, 7 fertilized (ICSI), 3 made it to day 5, 1 blast transferred

12dp5dt beta 685 - BFP! Due 31st March 2017 - thankful to so many people on this difficult journey


#5175 GardenerWife

GardenerWife
  • Just Hatched
  • 4 posts
  • Gender:Female
  • Location:ON
  • Dx:Male Factor
  • My Clinic:LHSC

Posted 26 January 2017 - 06:01 PM

Hi Kath,

Thanks for the reply. And congrats on your pregnancy! I think it's especially amazing after infertility as these little ones are so wanted. That's around what I thought it would be cost wise for us, we'll find that bit out soon. I'm scared they won't find anything during the PESA but only time will tell. I feel that because we had sperm before it's possible. If only I could bypass the next 2 months until the test!

Me- 34 / DH 36

TTC since early 2015

Feb 2016 - diagnosed with severe MFI 

Sept 2016 - dx azoospermia / low hormones so DH starts clomid 

Jan 2017 - still no sperm

Now just trying to figure out how to make this work.