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Side Effects from Stim Drugs...Share your experience


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#1 nicole999

nicole999
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Posted 28 August 2012 - 12:25 AM

I've been reading everyone's posts about side effects from fertility drugs and thought I would start a new topic on this so we can all share our experiences.

Some of what I experienced last few months after flare cycle with Superfact, Gonal F, Lupron and progesterone and estrogen:

Superfact - bad headaches deep inside head....like deep in the brain...nothing would help ease pain).

Brown age spots on face after IVF (not sure from what drug).

Yeast infection in rectum (told by family doctor quite common with hormones and fertility meds). This last one was embarrassing with itching and severe irritation. I suffered for 2.5 months afterwards until I had the courage to go to doc.

.....on to FET next month, hopefully things will go better, keeping our fingers crossed!

#2 #3@44

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Posted 28 August 2012 - 03:29 PM

Hello!
BCP - nothing.
Lupron - ovaries ache mildly, headaches.
Bravelle and/or menopur - ovaries ache, ache, ache. Bloatedness. CONSTIPATION. Slightly bad skin (I am old - I never get skin stuff anymore). Volatile emotions. Extra CM. Ridiculously dehydrated. Some morning nausea at end?? mildly sore boobs.
Lupron and/or bravelle/menopur - stuffy nose (sinuses), fatigue (?). Near end of stim - swollen feet (they hurt) and abdomen
Antibiotics - upset stomach if not taken with food (duh...)
Prometrium - fatigue, and a vaginal cyst (sorry - tmi) that eventually went away after about 3 weeks. Too much mess! Super sore boobs!

oh! and after BFN, biggest AF ever.
Me - 44, DH - 45
3 CONSECUTIVE IVF CYCLES AT 43 YEARS OLD = 16 eggs > 13 embryos > 10 transferred > 1 BABY!!!!


Years of anovulation (but this has saved me some eggs for my 40's!) and decreased count/motility.
4 years of trying naturally and tests - then surprise pregnancy in 2003, DD born 11/2003
6 cycles of clomid/iui - BFN, 2 cycles of FSH/IUI - x2 chemical pregnancy, 1 cycle of FSH/IUI - bfp! DS born 08/2006

2009 I decide I want another. Crazy I know - DH has had Vx.
2012 DH finally on board. Has TESE (super ouch).
03/12 and 04/12: FSH = 5, AFC = 4
IVF#1 - June 2012 - long lupron, 300 Bravelle, 150 Menopur, ICSI - 10 follicles, 3 eggs (WTF??), 2 fertilized, transferred 2 Day 3 4-cells - bfn.
IVF#2 - Aug/Sept 2012 - flare, 450 Bravelle, ICSI, 5 eggs, 4 fertilized, transferred 4 (2 8-cell, 2 10-cell) - chemical

IVF#3 - LAST CHANCE FOR ROMANCE![/b]
Oct/Nov 2012 - flare, lupron BID, 450 Bravelle, ICSI
Sept 15 - start BCP
Oct 11 - endo biopsy
Oct 14 - last BCP
Oct 17 - baseline: E2=286, start lupron microdose twice daily
Oct 19 - start 450 Bravelle
Oct 24 - U/S: 7 10mm follicles, bw: E2=964
Oct 26 - U/S, bw 9 follicles (all 10 -16mm), bw: E2=1867, lining: 9mm
Oct 28, u/s, bw 9 follicles (1 @10mm, 7 @16-17mm, 1 @23.5mm), bw: 3600+, lining: 10mm

Oct 29, u/s, bw 9 follicles (1 @12mm, 8 @18-21mm), bw: 5500+, lining: 10mm - trigger AND 450 Bravelle!
Oct 31 - ER 8 eggs!
Nov 1 - 7 fertilised!
Nov 2 - three grade 2 (all 4-cell), two grade 3 (2-cell and 5-cell) and two grade 4 (all 5-cell)
Nov 3 -two grade 2 (all 8-cell), four grade 3 (8-cell and 10-cell) and one grade 4 (6-cell)

Nov 4 - four good morulas, one border-line quality morula, two 10-cell embies
Nov 5 - ET of 2 blasts (2BB, 3BA), one cavitating morula and one other crap morula - NO FROSTIES!

Nov 10 - Day 10 - HPT ---- BFP!
Nov 14 - beta = 78

Nov 16 - beta = 179
Dec 7 - first u/s! 7w2d: CRL=10mm, HR=139
Dec 11 - first appt w/ high risk OB & another in office u/s (all good)
Dec 18 - u/s 8w6d: CRL=21mm, HR=172
Dec 27 - genetic testing and consult
Jan 11 - nuchal testing and IPS with soft markers (FTS) (for fun as will have already done NIPS) - NT=1.19mm = PERFECT
Jan 21 - 13w5d on u/s - we are having a boy!!!!!
July 24 - due! induced on July 6th - healthy, 7 lbs 2 oz at 37w3d - can't believe this happened!!

#3 Juliet

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Posted 28 August 2012 - 03:42 PM

The two main side effects I found in general with Puregon injections and stimming in general...

1) quite sore boobs... like I wore a sportsbra to bed for months, and hated shaving legs in the shower... leaning over = ouch!!

2) weight gain. I exercised almost every day through the first half of IUI cycles (before ovaries felt too heavy/uncomfortable) and when suppressing for IVF. Usually if I exercise every day or every other day (even 30 minutes at the gym + weights) I at least maintain my weight. It didn't seem any exercise I did impacted me at all when cycling, and in fact it was surprisingly easy to put on weight.