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Assisted Oocyte Activation


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#1 cheers

cheers
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  • Gender:Female
  • Dx:Male Factor

Posted 16 July 2012 - 11:30 AM

Hello ladies, just wondering whether anyone has done assisted oocyte activation with calcium ionophore. It is speculated to be useful when the fertilization rates with ICSI are poor. I don't think there are many clinics in Canada that use it but there are a couple of clinics in Toronto that use this technique.

I also know that the Colorado Centre for Reproductive Medicine (CCRM) uses this procedure to treat these situations.

Thanks!

Been ttc for 4 years
Dx: low morphology
1st IVF with ICSI: bfp but ended in a m/c at 5 weeks
Had initial consult with our new clinic - all screening bloodwork results are good; dna frag is high end of normal; karyotyping results are normal for dh.
February 26th called with my day 1.  Will start lupron on day 21 to down regulate.  Here we go again, hang on for the ride!! March 30th first puregon shot (day 3)
ER on April 11th - 34 eggs (ouch!)
Fertilization update - 30 mature eggs and all fertilized (holy cow!). Praying they keep growing!
April 16 - day 5 ET of 2 embryos
April 26 - BETA BFP!!!
7 week scan - 2 babies measuring on track with two good heartbeats!!! We are team PINK! Our miracle baby girls are here and we are in heaven!


#2 hockeybabe13

hockeybabe13
  • Cyclebase
  • 362 posts
  • Gender:Female
  • Location:Vaughan, ON
  • Interests:Having a baby!!! lol
  • Dx:Male Factor
  • My Clinic:Astra Fertlity Centre

Posted 16 July 2012 - 02:39 PM

I've used is in 2 of my IVFs at Astra Fertility in Mississauga, and have seen our fertilization rate increase. Best of luck to you. :)

Me: 31 DH: 37
Me: PCOS, Endometriosis, Insulin Resistance
DH: Severe male factor

IVF#1 Sept 2009 with ICSI
Oct 9 BFN :*(

IVF #2 February 1, 2010
Beta Feb 27 BFP!!! 207
Beta #2 326
Beta #3 654
First 6 wk U/S March 15th - 2 sacs seen, but only one baby with hb of 110bpm
U/S #2 April 7 - One perfect little peanut, HB 163bpm
Anatomy scan June 9 - It's a GIRL!!!
Complete placenta previa at 32 and 36 wks
Scheduled C-section Oct 27, Water broke Oct 23.
Baby Sophia Faith born via c-section October 23, 2010 at 38w 1d

IVF #3 June 13 2012
Beta July 9 69.5

Beta#2 62
Beta#3 21....Bye little one - chemical

IVF#4 October 27 2012
Beta Nov 25 BFN

IVF#5 April 28 2013
Beta #1 May 26 104

Beta#2 May 28 176

1st Ultrasound 6w3d - one baby

2nd Ultrasound 8w3d - no h/b (d&c to be done) 

Bye my little one

 

 

 


#3 cheers

cheers
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  • 483 posts
  • Gender:Female
  • Dx:Male Factor

Posted 17 July 2012 - 07:58 AM

Thanks Hockey! This is the same clinic we are looking to switch to. Can I ask you whether the clinic mentioned that morphology was an issue? If its too personal to discuss on the boards but you don't mind discussing, a PM is fine with me!

Been ttc for 4 years
Dx: low morphology
1st IVF with ICSI: bfp but ended in a m/c at 5 weeks
Had initial consult with our new clinic - all screening bloodwork results are good; dna frag is high end of normal; karyotyping results are normal for dh.
February 26th called with my day 1.  Will start lupron on day 21 to down regulate.  Here we go again, hang on for the ride!! March 30th first puregon shot (day 3)
ER on April 11th - 34 eggs (ouch!)
Fertilization update - 30 mature eggs and all fertilized (holy cow!). Praying they keep growing!
April 16 - day 5 ET of 2 embryos
April 26 - BETA BFP!!!
7 week scan - 2 babies measuring on track with two good heartbeats!!! We are team PINK! Our miracle baby girls are here and we are in heaven!


#4 l_ouise

l_ouise
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  • 9 posts
  • Gender:Female
  • Dx:Male Factor
  • My Clinic:CARE UK

Posted 13 September 2012 - 08:46 AM

We have just had this technique.

We went from 5% fertilisation to 77% fertilisation :)

#5 cheers

cheers
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  • 483 posts
  • Gender:Female
  • Dx:Male Factor

Posted 20 September 2012 - 10:04 AM

Hi Louise - I hope things went well with your cycle! I would love an update if you want to share :)

Been ttc for 4 years
Dx: low morphology
1st IVF with ICSI: bfp but ended in a m/c at 5 weeks
Had initial consult with our new clinic - all screening bloodwork results are good; dna frag is high end of normal; karyotyping results are normal for dh.
February 26th called with my day 1.  Will start lupron on day 21 to down regulate.  Here we go again, hang on for the ride!! March 30th first puregon shot (day 3)
ER on April 11th - 34 eggs (ouch!)
Fertilization update - 30 mature eggs and all fertilized (holy cow!). Praying they keep growing!
April 16 - day 5 ET of 2 embryos
April 26 - BETA BFP!!!
7 week scan - 2 babies measuring on track with two good heartbeats!!! We are team PINK! Our miracle baby girls are here and we are in heaven!