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Low fertilization rates using ICSI help!

MF IVF ICSI BFN

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3 replies to this topic

#1 Heregoesnothing

Heregoesnothing

    Heregoesnothing

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  • Gender:Female
  • Location:Quebec
  • Dx:Male Factor
  • My Clinic:Procrea montreal

Posted 25 June 2012 - 07:34 PM

Hi Ladies,

I'm currently waiting for my WTF appointment following a BFN. We've had two cycles thus far, both pretty bad in my opinion!

The first cycle was as follows:

5 eggs retrieved
3 fertilized naturally... NO ICSI used! (60% fertilization rate... though kind of unfair stat given such a low # of eggs)
Cycle cancelled b/c non made it to blast

The second cycle was as follows:

13 mature eggs
5 fertilized using ICSI (38%)
3 made it to day 3... 2 were transferred.
1 made it to blast at day 6, but was too low quality to freeze


The embryologist told us these results were most likely due to egg quality as well having MF. I'm very confused as I am only 31 years old. Could this really be happening to me?

Any experiences/advice for my WTF appointment would be greatly appreciated!

"Courage doesn't always roar. Sometimes, courage is the tiny voice at the end of the day saying, 'I will try again tomorrow'"

Me: 32 - DH: 32
Dx: Male Factor

IVF #1
Feb. 14th - Suprefact nasal spray 5x/day
March 15: Egg Retrieval - Only 5 wee-guys. FX
March 19: Down to 3... waiting for them to blast
March 21: None of them blasted... cycle cancelled.


IVF #2
Waiting time in Qc. City is another YEAR! Made appointments in Montreal to cycle again soon.
Courage means trying again tomorrow... couldn't be truer than now...


May 3rd - Polyp in Uterus confirmed. IVF #2 Cancelled
May 25th - Hysteroscopy schedule. Let's hope they don't postpone! It would put me at cycle day 28, which means I could cycle again right away. FX and TX! - Done and Done. Moving on.


May 25th - polyp removed
May 26th - started gonalF and luveris
June 6th - retrieval - 13 eggs - 5 fertilized... 2 growing normally, 3 lagging behind.
June 9th - transfered two grade A embryos on Day 3. One blast at day 6 - but not good enough quality to freeze. First blast in 18 embryos. Not very good stats.
June 22 - pregnancy test @2:00 - BFFN. (You get the picture)


IVF #3
July 27th: started gonalF (250) and luveris (150) ... Trigger 1/2 dose of HCG
August 9th: Retrieval - 15 eggs retrieved, 14 mature
August 12th: (Day 3) 12 embryos still going in the lab. 3 superstars...

August 14th: Transferred 2 blasts. None to freeze
Aug. 27th: Beta positive - 922
Sept. 12: u/s #1 - revealed a tilted uterus. We saw a sac, but nothing else
Sept. 19: u/s #2 - There was growth and progress. We saw a sac, an embryo and fetal pole. DR said it was a beautiful embryo and sac... but still no h/b.
Sept. 25th: u/s #3 - We need a miracle! TBA... And then there was a heartbeat. Holly Molly this journey is so crazy.

McGill consultation pending...



#2 notalone2

notalone2
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  • Gender:Female
  • Dx:Male Factor
  • My Clinic:OFC

Posted 25 June 2012 - 07:38 PM

I would ask what you can do to improve egg quality and what they recommend your next steps are based on the low fertilization rates. Good luck
Feb 2010 natural bfp - miscarriage blighted ovum
March 2011 first meeting at Ofc - slight male factor poor morph
June 2011 iui - cancelled lead follicle grew too fast
July 2011 iui2 - 2 follicles - bfn
October 2011 iui3 - 1 lead follicle fee fast - bfn
January 2012 iui4 converted to ivf - 5 eggs retrieved 0 fertilization - no transfer
June 2012 ivf #2 12 eggs retrieved 9 mature 8 fertilized with iCsi - 2 blasts Transfered day 5, 2 frosties - bfn
Nov 2012 FET - thawed our only frosties (2) only one survived. Transfer 1 blast 3BB
BFP nov 20

#3 rokgerl

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  • Gender:Female
  • Location:Calgary, AB
  • Dx:Other

Posted 25 June 2012 - 08:53 PM

I too was told that I had egg quality issues after our first IVF. While my eggs fertilized fine, we had highly fragmented embryos, which points to an egg quality problem. Although I am a bit older than you (34 years old) they, and I, were completely surprised by these results. It was the furthest thing from what we expected. We did IVF #2 and had better growing embryos but the same fragmentation...I took DHEA for 8 weeks prior as well as CoQ10 and vitamin D. Although my 2nd IVF gave us a BFP, it sadly ended in m/c. Maybe ask them what they thicken of DHEA and CoQ10? Could be what you need to get that extra little boost!

Good luck!

#4 tjluvbug

tjluvbug
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  • Gender:Female
  • Dx:Male Factor
  • My Clinic:Genesis

Posted 25 June 2012 - 09:05 PM

We had really poor fertilization with our first ivf, I am also 31 yrs old and I was concerned about egg quality too. Doc sid that eggs looked good prior to fertilization, how did yours look? I had DH take lots of supplements and so did before our next cycle and we ended up doubling our fertilization.
TTC since 2006
IVF# 1
Chemical Pregnancy

March 2011 - hysteroscopy revealed 3 uterine polyps - surgery

IVF# 2
BFN

FET # 1
April 18 - 11dp5dt beta negative

FET# 2
June 6 - lining at 10.3mm
June 11- transfer of 1 4bb 6 day blast
June 22, 2012- BFP on hpt
June 25, 2012- 14dp5dt/ 5 weeks - beta 699
June 29,2012-18dp5dt/5 weeks 4days - beta 2737
July 2, 2012- 21dp5dt/6 weeks beta - beta 5547
July 11, 2012 - u/s revealed empty sac measuring 6 weeks 3 days - no hint of yolk sac or fetal pole.......devastated





Also tagged with one or more of these keywords: MF, IVF, ICSI, BFN