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Anyone with low AMH all else normal?


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#1 Leeloo

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Posted 20 February 2012 - 10:22 AM

Hi!

I am 27 and have AMH at 0,85.

Day 3 FSH and Oestradiol are right into normal range.

My cycles are regular and I detect my ovulation every month: ovarian ache, cervical mucus, little spotting in cervical mucus, basal temperature raise...)

Pelvic ultrasound showed normal sized ovaries and I big mature follicule ready to come out at day 15. (the report only mentionned this follicule but I remember also seeing smaller follicules around it and also smaller follicules on the other ovary - don't know how many...)

Hysterosonography showed a bunch of follicules (did not count) in both ovaries but bigger on one side at day 7. The RE even said "you see, there is a bunch of follicules on both sides, so you are not undergoing menaupose" - That was before he found out about the AMH!

I will be doing the day 3 antral follicule count next week... I am not too sure what to expect...

If I have normal AFC, normal FSH but low AMH, does that mean it is the quality of the follicules that is poor?
If AFC is indeed low, with normal FSH... Does this mean I am in early-early menaupose and FSH is likely to go up soon?
What is the difference between DOR and menaupose?
I am officially DOR because AMH is low?

Does anyone else has low AMH with normal everything-else?
TTC since March 2011
Me 27: All seems OK, however I don't do well with stimulation.
DH 30: low count (moderate) and morphology (severe), normal motility.

Sept.20.11: me: Pelvic ultrasound ok
Nov.16.11: him: 1st SA ok (hospital lab)
Dec.13.11: First meeting at fertility clinic - Referrals for further testing including 2nd SA due to doubts on 1st SA's methodology
Jan.6.12: him: 2nd SA - Low count, motility, morphology (severe)
Jan.6.12: me: Hormone blood tests (AMH, FSH, oestradiol)
Jan.11.12: me: Hysterosonography - clear tubes
Jan.17.12: him: 3rd SA + hormone blood test
Jan.30.12: him: Apt. with urologist; 3rd SA same as 2nd. mild varicocele, normal LH/FSH.
Feb.6.12: him: Apt. with urologist; Normal testosterone. Bacteria found in sperm. Antibiotics course for 2 weeks, will most likely improve sperm parameters but more motility than morphology. Awaiting genetic testing results; if OK will try varicocele surgery.
me: AMH slightly below normal. FSH/oestradiol normal;
We are now on the wait list for n-IVF + ICSI (2-3 months)...
Feb.23.12: him: Genetic tests are OK!!! New SA (4th) to confirm that bacteria is gone. Variococele surgery March 15!
Mar.1.12: me: Day 3 antral follicule count: 24!!! - Very very good AFC vs lowish AMH... I could do stimulated IVF if I wanted to afterall, but
I am told I need to have all my babies as soon as possible and if I wait too long my AFC will drop.
him: antibiotics and vitamins have made a huge improvement in motility; it is now within normal range. Morphology also
improved from 0% to 1%.
Mar.15.12: him: Varicocele surgery
May 2012: natural-IVF + ICSI #1 - Chemical pregnancy
June 2012: natural-IVF + ICSI #2 - No embryo - cycle cancelled
July 2012: Find out surgery did not improve sperm parameters.
Find out AMH is normal and first results were a mistake
September 2012: natural-IVF + ICSI #3 - Abnormal cell division - cycle cancelled
October 2012: Stimulated-IVF #1 - Antagonist -
- 12 retrieved, 3 mature(?!), 2 fertilized, low quality, did not make it to blast - Cycle cancelled
November 2012: natural-IVF + ICSI #4 - Good quality embryo transfered Dec. 6. Beta Dec.19: Negative
March 2013: Stimulated-IVF #2 - Short -
- 7 retrieved, 5 mature, 2 fertized, 1 3pn (not transfered), 1 lovely gr.1 9 cells. Beta April 2: 188, April 4: 642

#2 silverdollar

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Posted 20 February 2012 - 10:55 AM

At 27, even if your egg supply is decreased, the eggs you do have left should be good quality. Don't delay pursuing treatments, but don't sweat it either. You might start menopause at 42 instead of 52, but not likely next year or anything. Good luck to you.

Unexplained IF/ DOR. Began TTC in 2008.
After a wild and crazy ride on the treatment train, our baby GIRL arrived on Jan 6, 2012
Hold on.... Surprise spontaneous just 7 months postpartum while still breastfeeding!!! Baby boy born May 2, 2013
My heart couldn't be more full :)
 
Full details are now in my profile "About Me" page

#3 Leeloo

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Posted 20 February 2012 - 11:12 AM

Thank you so much! That makes me feel better. I have no intention of delaying !
TTC since March 2011
Me 27: All seems OK, however I don't do well with stimulation.
DH 30: low count (moderate) and morphology (severe), normal motility.

Sept.20.11: me: Pelvic ultrasound ok
Nov.16.11: him: 1st SA ok (hospital lab)
Dec.13.11: First meeting at fertility clinic - Referrals for further testing including 2nd SA due to doubts on 1st SA's methodology
Jan.6.12: him: 2nd SA - Low count, motility, morphology (severe)
Jan.6.12: me: Hormone blood tests (AMH, FSH, oestradiol)
Jan.11.12: me: Hysterosonography - clear tubes
Jan.17.12: him: 3rd SA + hormone blood test
Jan.30.12: him: Apt. with urologist; 3rd SA same as 2nd. mild varicocele, normal LH/FSH.
Feb.6.12: him: Apt. with urologist; Normal testosterone. Bacteria found in sperm. Antibiotics course for 2 weeks, will most likely improve sperm parameters but more motility than morphology. Awaiting genetic testing results; if OK will try varicocele surgery.
me: AMH slightly below normal. FSH/oestradiol normal;
We are now on the wait list for n-IVF + ICSI (2-3 months)...
Feb.23.12: him: Genetic tests are OK!!! New SA (4th) to confirm that bacteria is gone. Variococele surgery March 15!
Mar.1.12: me: Day 3 antral follicule count: 24!!! - Very very good AFC vs lowish AMH... I could do stimulated IVF if I wanted to afterall, but
I am told I need to have all my babies as soon as possible and if I wait too long my AFC will drop.
him: antibiotics and vitamins have made a huge improvement in motility; it is now within normal range. Morphology also
improved from 0% to 1%.
Mar.15.12: him: Varicocele surgery
May 2012: natural-IVF + ICSI #1 - Chemical pregnancy
June 2012: natural-IVF + ICSI #2 - No embryo - cycle cancelled
July 2012: Find out surgery did not improve sperm parameters.
Find out AMH is normal and first results were a mistake
September 2012: natural-IVF + ICSI #3 - Abnormal cell division - cycle cancelled
October 2012: Stimulated-IVF #1 - Antagonist -
- 12 retrieved, 3 mature(?!), 2 fertilized, low quality, did not make it to blast - Cycle cancelled
November 2012: natural-IVF + ICSI #4 - Good quality embryo transfered Dec. 6. Beta Dec.19: Negative
March 2013: Stimulated-IVF #2 - Short -
- 7 retrieved, 5 mature, 2 fertized, 1 3pn (not transfered), 1 lovely gr.1 9 cells. Beta April 2: 188, April 4: 642

#4 leigh14

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Posted 20 February 2012 - 11:49 AM

Leeloo,

I have a lowish AMH but present normally in terms of my other hormones (estrogen and FSH). Sometimes women with a low AMH tend to produce fewer eggs but keep in mind that quantity and quality are two different things. And sometimes people with a low AMH respond well to treatment too. A lot depends on protocol. You can have good quality eggs in there but have a low AMH! I think that this is especially the case at age 27. I am currently 17 weeks pregnant and have a low AMH and only had two eggs retrieved after doing a low stim cycle--and I was 39 at the time of my cycle. So...stay hopeful!

Best of luck to you!

Leigh
Me: 40
Dx: DH: Vasectomy; need IVF/ICSI ME: D.O.R. and many immunological issues. (Initially presented as "normal" but issues were only discovered after IVF attempt #2 and #3 after testing at new clinic)
IVF attempt #1 Nov.2009, Age 37: Long "Lupron" protocol
Dec.2009: Cycle cancelled due to oversuppression
IVF attempt #2, Age 38: April 2010: 3 eggs retrieved, 2 mature, 2 fertilized, ET of 2 embryos BFN
IVF atempt #3 at new clinic: November 2010, Age 38: 5 eggs retrieved, 4 mature, 4 fertilized, ET of 2 blastocysts BFP
Strong beta numbers but babies not measuring on track but one heartbeat is present. Followup u/s reveals no HB's :( Had D&C--so sad.
Moved to new clinic closer to home + more of a focus on testing for potential immunological factors:
Further testing reveals three mutations related to inherited thrombophilia (2 MTHFR mutations and PA1-1 mutation), positive ANA, elevated NK cells and cytokines and low levels of leukocyte antibodies (LADS), Recommended Immunological treatment: Humira, LIT, IVig and blood thinners if PG
IVF Protocol: Low stim for me/ TESE needed for DH; took Humira in late August and early September; taking DHEA plus Co-Enzyme Q10, vitamins for DH just for good measure! September--two trips to Mexico for LIT treatment, treatments 3 weeks apart
Initial re-testing through Alan Beer Centre after some of the immune treatments reveals only cytokines were lowered, NKs still high and LAD numbers still low. Another LIT in Mexico is recommended. We decide to begin cycle on doctor's recommendation of just doing IVIG.
IVF#4, Age 39 : November 2011: Worst AFC EVER--a whopping 4! Three follicles responded, two eggs were retrieved. Three day transfer of two Grade 1 8 cell embryos: "Fahita" & "Burrito" Stick, stick, stick little ones!
BFP! Beta of 569
Viability u/s at 6 w 2d shows TWO babies measuring on track with heartbeats of 121. Looks like babies might be sharing the same amniotic sac.
Second u/s at 7w 2 d shows ONE baby with hb of 150, measuring 7 w 3 days. No sign of twin. Vanishing twin syndrome?
Third u/s at 8 w 2d shows ONE baby with hb of 170, measuring 8 w 3 days. Looks like a little jellybean!
12 week u/s at 12 w 2 days and baby is measuring 12 w 5 days with a heart beat of 150. Baby mooned us and waved at us with one hand....looked like a "royal" wave to me!
13 week doctor's appointment, HB=155 on doppler
14 week u/s to check cervix, HB=148
16 week u/s to check cervix, HB=138, baby had hiccups!
20 week u/s--everything looks good! HB=130, looks like we're having a GIRL!
IPS results very good!
39 weeks: Our baby girl arrived!!! She is healthy and beautiful! We are so happy! :)

Lilypie Maternity tickers

#5 Leeloo

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Posted 20 February 2012 - 03:06 PM

Thanks! That's also what my gynecologist thinks... With my cycles being regular, good temperature charts and everything else normal, he thinks that I do produce one good quality egg every month. So he is recommending natural IVF. Is low stim cycle the same as natural IVF or something in between?
TTC since March 2011
Me 27: All seems OK, however I don't do well with stimulation.
DH 30: low count (moderate) and morphology (severe), normal motility.

Sept.20.11: me: Pelvic ultrasound ok
Nov.16.11: him: 1st SA ok (hospital lab)
Dec.13.11: First meeting at fertility clinic - Referrals for further testing including 2nd SA due to doubts on 1st SA's methodology
Jan.6.12: him: 2nd SA - Low count, motility, morphology (severe)
Jan.6.12: me: Hormone blood tests (AMH, FSH, oestradiol)
Jan.11.12: me: Hysterosonography - clear tubes
Jan.17.12: him: 3rd SA + hormone blood test
Jan.30.12: him: Apt. with urologist; 3rd SA same as 2nd. mild varicocele, normal LH/FSH.
Feb.6.12: him: Apt. with urologist; Normal testosterone. Bacteria found in sperm. Antibiotics course for 2 weeks, will most likely improve sperm parameters but more motility than morphology. Awaiting genetic testing results; if OK will try varicocele surgery.
me: AMH slightly below normal. FSH/oestradiol normal;
We are now on the wait list for n-IVF + ICSI (2-3 months)...
Feb.23.12: him: Genetic tests are OK!!! New SA (4th) to confirm that bacteria is gone. Variococele surgery March 15!
Mar.1.12: me: Day 3 antral follicule count: 24!!! - Very very good AFC vs lowish AMH... I could do stimulated IVF if I wanted to afterall, but
I am told I need to have all my babies as soon as possible and if I wait too long my AFC will drop.
him: antibiotics and vitamins have made a huge improvement in motility; it is now within normal range. Morphology also
improved from 0% to 1%.
Mar.15.12: him: Varicocele surgery
May 2012: natural-IVF + ICSI #1 - Chemical pregnancy
June 2012: natural-IVF + ICSI #2 - No embryo - cycle cancelled
July 2012: Find out surgery did not improve sperm parameters.
Find out AMH is normal and first results were a mistake
September 2012: natural-IVF + ICSI #3 - Abnormal cell division - cycle cancelled
October 2012: Stimulated-IVF #1 - Antagonist -
- 12 retrieved, 3 mature(?!), 2 fertilized, low quality, did not make it to blast - Cycle cancelled
November 2012: natural-IVF + ICSI #4 - Good quality embryo transfered Dec. 6. Beta Dec.19: Negative
March 2013: Stimulated-IVF #2 - Short -
- 7 retrieved, 5 mature, 2 fertized, 1 3pn (not transfered), 1 lovely gr.1 9 cells. Beta April 2: 188, April 4: 642

#6 leigh14

leigh14
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Posted 20 February 2012 - 05:53 PM

Leeloo,

Low-stim is pretty much just like a normal IVF but with fewer drugs. I was just on Puregon (150) whereas in my previous cycles I had been on much higher doses. My doctor felt that with low stim we would try to get a few good quality eggs. I think he felt that sometimes higher dose meds could impair egg quality.

Good luck!

Leigh
Me: 40
Dx: DH: Vasectomy; need IVF/ICSI ME: D.O.R. and many immunological issues. (Initially presented as "normal" but issues were only discovered after IVF attempt #2 and #3 after testing at new clinic)
IVF attempt #1 Nov.2009, Age 37: Long "Lupron" protocol
Dec.2009: Cycle cancelled due to oversuppression
IVF attempt #2, Age 38: April 2010: 3 eggs retrieved, 2 mature, 2 fertilized, ET of 2 embryos BFN
IVF atempt #3 at new clinic: November 2010, Age 38: 5 eggs retrieved, 4 mature, 4 fertilized, ET of 2 blastocysts BFP
Strong beta numbers but babies not measuring on track but one heartbeat is present. Followup u/s reveals no HB's :( Had D&C--so sad.
Moved to new clinic closer to home + more of a focus on testing for potential immunological factors:
Further testing reveals three mutations related to inherited thrombophilia (2 MTHFR mutations and PA1-1 mutation), positive ANA, elevated NK cells and cytokines and low levels of leukocyte antibodies (LADS), Recommended Immunological treatment: Humira, LIT, IVig and blood thinners if PG
IVF Protocol: Low stim for me/ TESE needed for DH; took Humira in late August and early September; taking DHEA plus Co-Enzyme Q10, vitamins for DH just for good measure! September--two trips to Mexico for LIT treatment, treatments 3 weeks apart
Initial re-testing through Alan Beer Centre after some of the immune treatments reveals only cytokines were lowered, NKs still high and LAD numbers still low. Another LIT in Mexico is recommended. We decide to begin cycle on doctor's recommendation of just doing IVIG.
IVF#4, Age 39 : November 2011: Worst AFC EVER--a whopping 4! Three follicles responded, two eggs were retrieved. Three day transfer of two Grade 1 8 cell embryos: "Fahita" & "Burrito" Stick, stick, stick little ones!
BFP! Beta of 569
Viability u/s at 6 w 2d shows TWO babies measuring on track with heartbeats of 121. Looks like babies might be sharing the same amniotic sac.
Second u/s at 7w 2 d shows ONE baby with hb of 150, measuring 7 w 3 days. No sign of twin. Vanishing twin syndrome?
Third u/s at 8 w 2d shows ONE baby with hb of 170, measuring 8 w 3 days. Looks like a little jellybean!
12 week u/s at 12 w 2 days and baby is measuring 12 w 5 days with a heart beat of 150. Baby mooned us and waved at us with one hand....looked like a "royal" wave to me!
13 week doctor's appointment, HB=155 on doppler
14 week u/s to check cervix, HB=148
16 week u/s to check cervix, HB=138, baby had hiccups!
20 week u/s--everything looks good! HB=130, looks like we're having a GIRL!
IPS results very good!
39 weeks: Our baby girl arrived!!! She is healthy and beautiful! We are so happy! :)

Lilypie Maternity tickers

#7 Leeloo

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Posted 20 February 2012 - 07:59 PM

I guess I'll talk about that with the doctor... It seemed to me like my options were only full-stim IFV or natural-IVF... Low stim may give me a chance to get 2 or 3 eggs... Although it might not be offered because of the founding system... Here in Quebec, public insurance pays for 6 cycles of natural IVF OR 3 cycles of stimulated IVF... So I don't know how they deal with low stim... I guess if they count it like stimulated, I'd rather have 6 natural than 3 low-stim... I dunno... Will talk with the doctor...

Thanks again!
TTC since March 2011
Me 27: All seems OK, however I don't do well with stimulation.
DH 30: low count (moderate) and morphology (severe), normal motility.

Sept.20.11: me: Pelvic ultrasound ok
Nov.16.11: him: 1st SA ok (hospital lab)
Dec.13.11: First meeting at fertility clinic - Referrals for further testing including 2nd SA due to doubts on 1st SA's methodology
Jan.6.12: him: 2nd SA - Low count, motility, morphology (severe)
Jan.6.12: me: Hormone blood tests (AMH, FSH, oestradiol)
Jan.11.12: me: Hysterosonography - clear tubes
Jan.17.12: him: 3rd SA + hormone blood test
Jan.30.12: him: Apt. with urologist; 3rd SA same as 2nd. mild varicocele, normal LH/FSH.
Feb.6.12: him: Apt. with urologist; Normal testosterone. Bacteria found in sperm. Antibiotics course for 2 weeks, will most likely improve sperm parameters but more motility than morphology. Awaiting genetic testing results; if OK will try varicocele surgery.
me: AMH slightly below normal. FSH/oestradiol normal;
We are now on the wait list for n-IVF + ICSI (2-3 months)...
Feb.23.12: him: Genetic tests are OK!!! New SA (4th) to confirm that bacteria is gone. Variococele surgery March 15!
Mar.1.12: me: Day 3 antral follicule count: 24!!! - Very very good AFC vs lowish AMH... I could do stimulated IVF if I wanted to afterall, but
I am told I need to have all my babies as soon as possible and if I wait too long my AFC will drop.
him: antibiotics and vitamins have made a huge improvement in motility; it is now within normal range. Morphology also
improved from 0% to 1%.
Mar.15.12: him: Varicocele surgery
May 2012: natural-IVF + ICSI #1 - Chemical pregnancy
June 2012: natural-IVF + ICSI #2 - No embryo - cycle cancelled
July 2012: Find out surgery did not improve sperm parameters.
Find out AMH is normal and first results were a mistake
September 2012: natural-IVF + ICSI #3 - Abnormal cell division - cycle cancelled
October 2012: Stimulated-IVF #1 - Antagonist -
- 12 retrieved, 3 mature(?!), 2 fertilized, low quality, did not make it to blast - Cycle cancelled
November 2012: natural-IVF + ICSI #4 - Good quality embryo transfered Dec. 6. Beta Dec.19: Negative
March 2013: Stimulated-IVF #2 - Short -
- 7 retrieved, 5 mature, 2 fertized, 1 3pn (not transfered), 1 lovely gr.1 9 cells. Beta April 2: 188, April 4: 642

#8 Leeloo

Leeloo
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Posted 01 March 2012 - 08:50 PM

I got a surprising AFC count of 24 today!!! I saw 2 doctors and both of them were quite puzzled about the discrepancy between an awesome AFC count and a lowish AMH... They concluded that AFC was more reliable, that it would be OK for me to do stimulated IVF if I wanted to, and that the implication of my low AMH would be that I shouldn't wait too much between children. I am still gonna go for natural as we are already on the list and I like the idea of not getting so much medication, we'll switch to stimulation after 1 or 2 if it fails.
TTC since March 2011
Me 27: All seems OK, however I don't do well with stimulation.
DH 30: low count (moderate) and morphology (severe), normal motility.

Sept.20.11: me: Pelvic ultrasound ok
Nov.16.11: him: 1st SA ok (hospital lab)
Dec.13.11: First meeting at fertility clinic - Referrals for further testing including 2nd SA due to doubts on 1st SA's methodology
Jan.6.12: him: 2nd SA - Low count, motility, morphology (severe)
Jan.6.12: me: Hormone blood tests (AMH, FSH, oestradiol)
Jan.11.12: me: Hysterosonography - clear tubes
Jan.17.12: him: 3rd SA + hormone blood test
Jan.30.12: him: Apt. with urologist; 3rd SA same as 2nd. mild varicocele, normal LH/FSH.
Feb.6.12: him: Apt. with urologist; Normal testosterone. Bacteria found in sperm. Antibiotics course for 2 weeks, will most likely improve sperm parameters but more motility than morphology. Awaiting genetic testing results; if OK will try varicocele surgery.
me: AMH slightly below normal. FSH/oestradiol normal;
We are now on the wait list for n-IVF + ICSI (2-3 months)...
Feb.23.12: him: Genetic tests are OK!!! New SA (4th) to confirm that bacteria is gone. Variococele surgery March 15!
Mar.1.12: me: Day 3 antral follicule count: 24!!! - Very very good AFC vs lowish AMH... I could do stimulated IVF if I wanted to afterall, but
I am told I need to have all my babies as soon as possible and if I wait too long my AFC will drop.
him: antibiotics and vitamins have made a huge improvement in motility; it is now within normal range. Morphology also
improved from 0% to 1%.
Mar.15.12: him: Varicocele surgery
May 2012: natural-IVF + ICSI #1 - Chemical pregnancy
June 2012: natural-IVF + ICSI #2 - No embryo - cycle cancelled
July 2012: Find out surgery did not improve sperm parameters.
Find out AMH is normal and first results were a mistake
September 2012: natural-IVF + ICSI #3 - Abnormal cell division - cycle cancelled
October 2012: Stimulated-IVF #1 - Antagonist -
- 12 retrieved, 3 mature(?!), 2 fertilized, low quality, did not make it to blast - Cycle cancelled
November 2012: natural-IVF + ICSI #4 - Good quality embryo transfered Dec. 6. Beta Dec.19: Negative
March 2013: Stimulated-IVF #2 - Short -
- 7 retrieved, 5 mature, 2 fertized, 1 3pn (not transfered), 1 lovely gr.1 9 cells. Beta April 2: 188, April 4: 642

#9 Charliedo

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Posted 21 November 2013 - 04:12 PM

Hi Leelo,

 

I have a low AMH of 0.84

My FSH and LH are normal.

 

Last cycle going for IUI, I had one perfectly normal big egg developing and bunch of other follicles were showing.

 

The IUI was unsuccessful.

 

Also DH sperm count was 2 million last time but for IUI 17 million after wash.

 

I know Im ovulating just fine because Ive been doing the ovulation tests, many ultrasounds with clomid cycles and just recently at my sonohyst.

 

I feel at a loss when the doctor tells me to take clomid. When im already making eggs why do i need clomid.

What does low amh mean when everything else is normal.

 

Best,